Ann Pediatr Endocrinol Metab.  2013 Jun;18(2):45-54. 10.6065/apem.2013.18.2.45.

The pleiomorphic actions of vitamin D and its importance for children

• Kim SY

• KMID: 2047460
• DOI: http://doi.org/10.6065/apem.2013.18.2.45

Abstract

Knowledge regarding the physiological role and dietary requirements of vitamin D has dramatically expanded over the past several decades. The "new" vitamin D is not only a mediator of calcium homeostasis, it also has important immunomodulatory, antimicrobial, and antiproliferative actions. In spite of the interest in vitamin D as a mediator in many chronic diseases of adulthood such as cancer and type II diabetes, less attention has been given to the implications of the new understanding of vitamin D for child and adolescent health. Recently, rickets caused by vitamin D deficiency is resurging in developed countries. Therefore, pharmacokinetic studies and epidemiologic research that incorporates clinical and functional outcomes are needed to clarify the role of vitamin D in growth and development in Korean children and adolescents and to determine vitamin D dietary requirements.

Keyword

Vitamin D; Vitamin D receptor; Child; Growth

MeSH Terms

Adolescent
Calcium
Child
Chronic Disease
Developed Countries
Growth and Development
Homeostasis
Humans
Nutritional Requirements
Receptors, Calcitriol
Rickets
Vitamin D
Vitamin D Deficiency
Vitamins
Calcium
Receptors, Calcitriol
Vitamin D
Vitamins