J Korean Rheum Assoc.  1995 Jan;2(1):82-86.

A Case Of Dermatomyositis Associated With Uterine Cervical Cancer

• Kyung KS
• Song YS
• Kim JS
• Han SH
• Lee HK
• Lee YW

Abstract

Dermatomyositis is a group of connective tissue disorders characterized by non-suppurative inflammation of the skeletal muscle and skin lesions. It is associated with malignancy, especially of the stomach, lung, overy and breast. we report a case of dermatomyositis with uterine cervical concer. A 78 year old female patient was admitted because of progressive proximal muscle weakness, skin rashes, and vaginal spotting. She was bedridden because of severe proximal muscle weakness and atrophy, unable to elevate her head, and suffered from dysphagia. Gottron's patches were found on the knuckles of the hands, scaly erythematous rashes on the extensor surfaces of bilateral elbows, wrists and knees. The serum concentrations of muscle enzymes were elevated, the biopsy of quadriceps muscle showed the features comparable with myositis, and the uterine cervical biopsy revealed squamous cell carcinoma, which was determined to be in stage lib by pelvic CT. Radiotherapy(total 3240 cGy) was done for the cervical cancer and prednisolone (initially 60mg/day) was given for the dermatomyositis. The muscle power improved only a little although the concentrations of serum muscle enzmes returned to normal. She deceased of aspiration pneumonia 43 days after the admission.

Keyword

Dermatomyositis; Uterine cervical cancer

MeSH Terms

Aged
Atrophy
Biopsy
Breast
Carcinoma, Squamous Cell
Connective Tissue
Deglutition Disorders
Dermatomyositis*
Elbow
Exanthema
Female
Hand
Head
Humans
Inflammation
Knee
Lung
Metrorrhagia
Muscle Weakness
Muscle, Skeletal
Myositis
Pneumonia, Aspiration
Prednisolone
Quadriceps Muscle
Skin
Stomach
Uterine Cervical Neoplasms*
Wrist
Prednisolone