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Impact of Sarcopenia on the Risk of Erosive Esophagitis

Heo CM, Kim TJ, Lee H, Pyo JH, Min YW, Min BH, Lee JH, Son HJ, Baek SY, Kim K, Ryu S, Rhee PL, Kim JJ

BACKGROUND/AIMS: An association between obesity and erosive esophagitis has been reported, but the effects of sarcopenia and obesity on erosive esophagitis are unknown. This study examined the relationship between obesity,...
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Impact of Skeletal Muscle Mass on Metabolic Health

Kim G, Kim JH

Skeletal muscle is regarded as an endocrine and paracrine organ. Muscle-derived secretory proteins, referred to as myokines, mediate interactions between skeletal muscle mass and other organs such as the liver,...
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Combined Aerobic and Resistance Exercise Training Reduces Circulating Apolipoprotein J Levels and Improves Insulin Resistance in Postmenopausal Diabetic Women

Jeon YK, Kim SS, Kim JH, Kim HJ, Kim HJ, Park JJ, Cho YS, Joung SH, Kim JR, Kim BH, Song SH, Kim IJ, Kim YK, Kim YB

BACKGROUND: Circulating apolipoprotein J (ApoJ) is closely associated with insulin resistance; however, the effect of exercise on circulating ApoJ levels and the association of ApoJ with metabolic indices remain unknown....
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Prognostic Value of Skeletal Muscle Depletion Measured on Computed Tomography for Overall Survival in Patients with Non-Metastatic Breast Cancer

Huh J, Park B, Lee H, An YS, Jung Y, Kim JY, Kang DK, Kim KW, Kim TH

PURPOSE: The purpose of this study was to evaluate the prognostic value of skeletal muscle depletion measured on computed tomography (CT) in patients with non-metastatic invasive breast cancer. METHODS: This retrospective...
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Assessment of neovascularization during bone healing using contrast-enhanced ultrasonography in a canine tibial osteotomy model: a preliminary study

Jeon S, Jang J, Lee G, Park S, Lee SK, Kim H, Choi J

Blood perfusion of skeletal muscle and callus was evaluated using contrast-enhanced ultrasonography (CEUS) in a canine osteotomy model to determine the applicability of CEUS in the assessment of neovascularization during...
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Development and Validation of a Deep Learning System for Segmentation of Abdominal Muscle and Fat on Computed Tomography

Park HJ, Shin Y, Park J, Kim H, Lee IS, Seo DW, Huh J, Lee TY, Park T, Lee J, Kim KW

OBJECTIVE: We aimed to develop and validate a deep learning system for fully automated segmentation of abdominal muscle and fat areas on computed tomography (CT) images. MATERIALS AND METHODS: A fully...
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Diabetic Peripheral Neuropathy as a Risk Factor for Sarcopenia

Oh TJ, Song Y, Moon JH, Choi SH, Jang HC

BACKGROUND: Diabetic peripheral neuropathy (DPN) is prevalent in patients with type 2 diabetes, and its prevalence increases with age. A previous study demonstrated the association between DPN and muscle dysfunction;...
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Diabetes and Muscle Dysfunction in Older Adults

Jang HC

Aging and diabetes are both risk factors for functional decline or disability in older adults with diabetes. Recent studies demonstrated that the presence of diabetes significantly increases the risk of...
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Relationship between sarcopenia and pain catastrophizing in patients with lumbar spinal stenosis: A cross-sectional study

Wada T, Tanishima , Osaki M, Nagashima , Hagino H

OBJECTIVES: The purpose of this study is to clarify the psychological factors related to sarcopenia in patients with lumbar spinal stenosis (LSS). METHODS: This cross-sectional study included 72 patients with LSS...
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Arginine methylation as a key post-translational modification in skeletal muscle homeostasis: a review

Kim H, Kang JS, Jeong HJ

Arginine methylation mediated by protein arginine methyltransferases (PRMTs) has emerged as a key post-translational modification of histone or nonhistone substrates. It involves or controls signaling pathways or gene expression implicated...
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A familial case of limb-girdle muscular dystrophy with CAV3 mutation

Lee S, Jang S, Shim Y, Kim WJ, Kim SY, Cho A, Kim H, Kim JI, Lim BC, Hwang H, Choi J, Kim KJ, Chae JH

Limb-girdle muscular dystrophy (LGMD) is a group of muscular dystrophies that has extremely heterogeneous clinical features and genetic background. The caveolin-3 gene (CAV3) is one of the causative genes. LGMD...
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Clinical Use of Mesenchymal Stem Cells in Bone Regeneration

Park CW, Lim SJ, Park YS

Owing to the recent advances in biological knowledge on stem cells, many efforts are being made to apply them to clinical practice. Although mesenchymal stem cells were first found in...
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Serum myostatin levels are associated with abdominal aortic calcification in dialysis patients

Lee SM, Kim SE, Lee JY, Jeong HJ, Son YK, An WS

BACKGROUND: Serum myostatin levels are increased according to renal function decline and myostatin may be a main mediator of chronic kidney disease–related sarcopenia. A previous study reported that serum myostatin...
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Elucidation of the pathophysiology of intradialytic muscle cramps: pharmacokinetics applied to translational research

Atkinson A

In the conventional concept of translational research, investigations flow from the laboratory bench to the bedside. However, clinical research can also serve as the starting point for subsequent laboratory investigations...
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Anatomical Classification of Plantaris Tendon according to Shape and Location of Insertion in Korean

Park KR, Cho J, Choi YJ, Kim D, Kwon HW, Jang HJ, Kang H, Park J

The plantaris muscle is a small muscle with a short belly and long thin tendon that forms part of the posterior superficial compartment of the calf. The purpose of this...
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Hypertension Is Related to Positive Global Sagittal Alignment: A Cross-Sectional Cohort Study

Arima H, Togawa D, Hasegawa T, Yamato Y, Yoshida G, Kobayashi , Yasuda T, Banno T, Oe S, Mihara Y, Ushirozako H, Hoshino H, Matsuyama

STUDY DESIGN: Cross-sectional cohort study. PURPOSE: This study aimed to investigate the relationship between hypertension and spino-pelvic sagittal alignment in middle-aged and elderly individuals. OVERVIEW OF LITERATURE: Positive global sagittal alignment is...
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Association between energy intake and skeletal muscle mass according to dietary patterns derived by cluster analysis: data from the 2008 ~ 2010 Korea National Health and Nutrition Examination Survey

Jang BY, Bu SY

PURPOSE: This study investigated major dietary patterns among healthy Korean adults using cluster analysis and analyzed the relationship between energy intake and skeletal muscle mass. METHODS: This study was conducted using...
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Bilateral Corneal Opacities with Galactokinase Deficiency and Spinal Muscular Atrophy

Cho SY, Kim S, Chung SK

PURPOSE: To report a case of bilateral corneal opacities and rare spinal muscular atrophy type III (Kugelberg-Welander disease) in a galactokinase-deficiency patient. CASE SUMMARY: A 6-year-old female presented with bilateral ground...
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Adult Stem Cells in Hibernation: Future Perspectives of Space Travel

Chen YC, Aui SP, Lai YS, Chang KT

Space traveling is imperative for mankind in the future. Expectedly, hibernation will become an option for space traveler to overcome the endless voyage. With regard to some of the studies...
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Neuromyelitis Optica Spectrum Disorder Preceded by Myotonic Myopathy

Lee H, Kim D, Kim W, Choi K, Park SH, Oh J

Neuromyelitis optica spectrum disorder (NMOSD) is generally known as selective involvement of central nervous system. However, in recent years, some evidences have been found that NMOSD invades other peripheral organs....
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