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The mediating role of the left ventricular mass index on the relationship between the fluid balance and left ventricular diastolic function in patients with chronic kidney disease

Han BG, Lee JY, Kim JS, Yang JW, Park SW

Background: The pathophysiological mechanism of cardiovascular disease in patients with chronic kidney disease (CKD) is complicated. Mediation analysis is an important statistical tool for gaining insight into the complex mechanisms...
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Effect of Intravenous Thrombolysis Prior to Mechanical Thrombectomy According to the Location of M1 Occlusion

Ryu JC, Kwon B, Song Y, Lee DH, Chang JY, Kang DW, Kwon SU, Kim JS, Kim BJ

Background and Purpose The additive effects of intravenous thrombolysis (IVT) before mechanical thrombectomy (MT) remain unclear. We aimed to investigate the efficacy and safety of IVT prior to MT depending...
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Long term management of people with post-tuberculosis lung disease

Seo W, Kim HW, Kim JS, Min J

Post-tuberculosis lung disease (PTLD) is emerging as a significant area of global interest. As the number of patients surviving tuberculosis (TB) increases, the subsequent long-term repercussions have drawn increased attention...
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A Phase II Trial of Nintedanib in Patients with Metastatic or Recurrent Head and Neck Squamous Cell Carcinoma: In-Depth Analysis of Nintedanib Arm from the KCSG HN 15-16 TRIUMPH Trial

Kim KH, Lim SM, Ahn HK, Lee YG, Lee KW, Ahn MJ, Keam B, Kim HR, Lee HW, An HJ, Kim JS

Purpose Precision oncology approach for recurrent and metastatic head and neck squamous cell carcinoma (HNSCC) is necessary due to its dismal prognosis. We performed a genomic profile-based umbrella trial of...
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Lazertinib versus Gefitinib as First-Line Treatment for EGFR-mutated Locally Advanced or Metastatic NSCLC: LASER301 Korean Subset

Lee KH, Cho BC, Ahn MJ, Lee YG, Lee Y, Lee JS, Kim JH, Min YJ, Lee GW, Lee SS, Lee KH, Ko YH, Shim BY, Kim SW, Shin SW, Choi JH, Kim DW, Cho EK, Park KU, Kim JS, Chun SH, Wang J, Choi S, Kang JH

Purpose This subgroup analysis of the Korean subset of patients in the phase 3 LASER301 trial evaluated the efficacy and safety of lazertinib versus gefitinib as first-line therapy for epidermal...
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Interlaminar Endoscopic Lumbar Discectomy Versus Microscopic Lumbar Discectomy: A Preliminary Analysis of L5–S1 Lumbar Disc Herniation Outcomes in Prospective Randomized Controlled Trials

Liu Y, Kim Y, Park CW, Suvithayasiri S, Jitpakdee K, Kim JS

Objective: A preliminary report from a single institution, noninferiority, prospective randomized controlled trial is conducted to determine the effectiveness of interlaminar endoscopic lumbar discectomy (IELD) versus microscopic lumbar discectomy (MLD)...
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The Endoscopic Lumbar Interbody Fusion: A Narrative Review, and Future Perspective

Pholprajug P, Kotheeranurak V, Liu Y, Kim JS

Lumbar interbody fusion stands as a preferred surgical solution for degenerative lumbar spine diseases. The procedure primarily aims to establish lumbar segment stability, directly addressing patient symptoms associated with spinal...
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Comparative Efficacy of Surgical Interventions for Osteoporotic Vertebral Compression Fractures: A Systematic Review and Network Meta-analysis

Liu Y, Liu J, Suvithayasiri S, Han I, Kim JS

Objective: We aimed to comprehensively compare surgical methods for osteoporotic vertebral compression fracture (OVCF) using systematic review and network meta-analysis to understand their effectiveness and outcomes, as current research provides...
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Inferior Turbinate Swing Approach for Inaccessible Maxillary Sinus Lesions

Koh JH, Kim JS

Background and Objectives Maxillary sinus is easily accessible through endoscopic surgery; however, additional combined approaches may be required depending on primary lesions. These approaches are canine fossa approach (CFA), Caldwell-Luc...
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A Case-Control Clinical Trial on a Deep Learning-Based Classification System for Diagnosis of Amyloid-Positive Alzheimer’s Disease

Bae JB, Lee S, Oh H, Sung J, Lee D, Han JW, Kim JS, Kim JH, Kim SE, Kim KW

Objective A deep learning-based classification system (DLCS) which uses structural brain magnetic resonance imaging (MRI) to diagnose Alzheimer’s disease (AD) was developed in a previous recent study. Here, we evaluate...
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Computed tomography–assessed presarcopenia and clinical outcomes after laparoscopic surgery for rectal cancer

Song JH, Oh RK, Lee JE, Lee KH, Kim JY, Kim JS

Purpose: Previous studies have reported that presarcopenia negatively affects rectal cancer treatment. However, most studies have analyzed patients including majority of open surgery, and the association between presarcopenia and clinical...
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Effects of Intramuscular Epinephrine Injection and Systemic Sildenafil Citrate on Rat Transverse Rectus Abdominis Musculocutaneous Flap Survival

Lee DH, Yeo J, Park S, Cho SH, Kim S, Kim JS, Kim BG, Chang KH, Park JO

Background and Objectives Flaps are commonly employed for reconstruction, and many studies have sought to improve flap survival. In this study, we determined whether sildenafil and epinephrine synergistically improve the...
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Principles for effective management of scabies outbreaks

Seo HM, Kim JS

Background: The contagious skin infestation scabies, is caused by the mite Sarcoptes scabiei var. hominis. These microscopic organisms navigate under the skin surface to lay eggs, creating burrows that cause...
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Case Report: Reconstruction of the Lower Lip using the Karapandzic Flap

Kim JS, Shin JB, Kim NG, Do GC, Kim MH, Kim TH, Lee KS

Squamous cell carcinoma of the lip is a common malignant tumor originating from oral cancer. However, unlike other areas, the lips hold significant functional and aesthetic importance as a part...
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The Fracture Risk Assessment Tool Probability and Trabecular Bone Score Mediate the Relationship between Sphingosine 1-phosphate Levels and Fracture Risk

Lee SH, Kim JS, Koh JM

Background: The sphingosine 1-phosphate (S1P) concentration is a potential biomarker of osteoporotic fracture and is associated with both the fracture risk assessment tool (FRAX) probability and trabecular bone score (TBS),...
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Improved Detection of Urolithiasis Using High-Resolution Computed Tomography Images by a Vision Transformer Model

Choi HS, Kim JS, Whangbo TK, Eun SJ

Purpose: Urinary stones cause lateral abdominal pain and are a prevalent condition among younger age groups. The diagnosis typically involves assessing symptoms, conducting physical examinations, performing urine tests, and utilizing...
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Pediatricians’ perspectives on telemedicine for pediatric patients

Kim JS

Background: This study examined the characteristics of pediatric patients through surveys and in-depth interviews with pediatricians who have experience in telemedicine, and analyzed the current status of telemedicine in pediatrics...
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Exercise capacity and risk of incident atrial fibrillation in healthy adults

Kim JY, Cho SJ, Kim J, Chung TW, Park SJ, Park KM, Kim JS, On YK

Background/Aims: Atrial fibrillation (AF) is a common arrhythmia and is associated with cardiovascular morbidity and mortality. It is important to identify and control the modifiable risk factors of AF. We...
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Factors influencing occurrence of metachronous gastric cancer after endoscopic resection: a systematic review and meta-analysis

Choe Y, Park JM, Kim JS, Cho YK, Kim BW, Choi MG

Background/Aims: Metachronous gastric cancer (MGC) can occur after endoscopic resection for gastric cancer. Further studies on factors other than Helicobacter pylori infection are needed. This systematic review and meta-analysis aimed...
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Increased Resting-State Positron Emission Tomography Activity After Cochlear Implantation in Adult Deafened Cats

Park MH, Kim JS, Lee S, Kim DH, Oh SH

Objectives. Cochlear implants are widely used for hearing rehabilitation in patients with profound sensorineural hearing loss. However, Cochlear implants have variable results, and central neural plasticity is considered to be...
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