J Korean Neurosurg Soc.
1996 Aug;25(8):1679-1685.
Pleomorphic Xanthoastrocytoma: Report of 2 Cases
- Affiliations
-
- 1Department of Neurosurgery, College of Medicine, Chungang University, Seoul, Korea.
- 2Department of Pathology, College of Medicine, Chungang University, Seoul, Korea.
Abstract
- Pleomorphic xanthoastrocytoma is a recently characterized neoplasm with relatively favorable prognosis despite aggressive histological features. Two cases of pleomorphic xanthoastrocytoma involving the left temporal lobe are reported, both occurring in adolescents. The tumor is considered to arise from the subpial astrocytes of the superficial cortex. Electron microscopic examination and immunoperoxidase stains for glial fibrillary acidic protein(GFAP) are helpful in making a definitive histologic diagnosis. In contrast to malignant gliomas, pleomorphic xanthoastrocytoma does not appear to require aggressive postoperative radiation therapy or chemotherapy. Therefore, It is important to recognize and identify this type of glioma as a distinct entity.
