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Effects of retinoid-loaded hyaluronic acid nanomicelles on vaginal epithelium in a murine menopause model

Kim T, Chung HS, Lee HS, Uthaman S, Park IK, Park K

Purpose: This study aimed to develop hyaluronic acid (HA)-based, retinoic acid (RA)-containing nanomicelles and to investigate the effects of these newly developed nanomicelles on regeneration of the vaginal epithelium and...
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Development and Testing of a Machine Learning Model Using 18 F-Fluorodeoxyglucose PET/CT-Derived Metabolic Parameters to Classify Human Papillomavirus Status in Oropharyngeal Squamous Carcinoma

Woo C, Jo KH, Sohn B, Park K, Cho H, Kang WJ, Kim J, Lee SK

Objective: To develop and test a machine learning model for classifying human papillomavirus (HPV) status of patients with oropharyngeal squamous cell carcinoma (OPSCC) using 18 F-fluorodeoxyglucose ( 18 F-FDG) PET-derived...
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The Gangwon Obesity and Metabolic Syndrome Study: Methods and Initial Baseline Data

Cho YJ, Park S, Kim SS, Park HJ, Son JW, Lee TK, Hong S, Kang JH, Kim SM, Kim YH, Kim WJ, Seo YE, An Y, Rhee SY, Chon S, Jeon S, Park K, Kim BS, Lee CB, Kim KK, Lee JE

Background: The prevalence of obesity has been continuously increasing, especially in rural areas of South Korea. Therefore, it is important to examine various genetic, behavioral, and environmental factors associated with...
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Assessment of Disease Severity and Quality of Life in Patients with Atopic Dermatitis from South Korea

Son SW, Lee JH, Ahn J, Chang SE, Choi EH, Han TY, Jang YH, Kim HO, Kim MB, Kim YC, Ko HC, Ko JY, Lee SE, Lee YW, Lew BL, Na CH, Park CO, Park CW, Park KY, Park K, Park YL, Roh JY, Seo YJ, Shin MK, Lee S, Cho SH

Background: Data illustrating the impact of atopic dermatitis (AD) on lives of adults with AD in South Korea are limited. Objective: To assess the AD disease severity and its impact on...
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Development and Validation of MRI-Based Radiomics Models for Diagnosing Juvenile Myoclonic Epilepsy

Kim KM, Hwang H, Sohn B, Park K, Han K, Ahn SS, Lee W, Chu MK, Heo K, Lee SK

Objective: Radiomic modeling using multiple regions of interest in MRI of the brain to diagnose juvenile myoclonic epilepsy (JME) has not yet been investigated. This study aimed to develop and...
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Impact of diastolic dysfunction in patients with preserved ejection fraction undergoing permanent cardiac pacemaker placement

Jeong H, Kim H, Kim S, Kim H, Ki Y, Choi D, Park K, Lee K, Yoon N, Park H, Cho J

Background: Chronic right-ventricular (RV) pacing can exacerbate heart failure in patients with a low ejection fraction (EF). There is little information on the effects of diastolic dysfunction (DD) in patients...
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Rotational mechanical dilator sheaths for effective transvenous lead extraction

Park S, Kim J, Park K, On Y, Kim J

Background: An exponential rise in clinical demand for cardiac implantable electronic device (CIED) therapy is observed all over the world due to the rapidly expanding lifespan. Accordingly, appropriate lead management...
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Spinal orexin A attenuates opioid-induced mechanical hypersensitivity in the rat

Youn Dh, Jun J, Kim TW, Park K

Background: Repeated administration of opioid analgesics for pain treatment can produce paradoxical hyperalgesia via peripheral and/or central mechanisms. Thus, this study investigated whether spinally (centrally) administered orexin A attenuates opioid-induced...
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Laboratory Indicators for Convalescence in SARS-CoV-2 Positive Cases with High Ct Value

Na R, Park K, Sung H, Kim MN

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Long-Term Health Consequence of Discharged Patients with COVID-19: A Survey of Patients from Hospital Dedicated COVID-19 in 2021

Min J, Kim S, Choi J, Park H, Lee S, Cheung B, Park K

Background: Due to the prolonged coronavirus disease 2019 (COVID-19) pandemic, accumulating patients are experiencing long COVID symptoms. This study aimed to investigate whether COVID-19 sequelae affect individuals’ returns to daily...
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Impact of Enforcement of the Act to Improve Training Conditions and the Status of Medical Residents in Emergency Abdominal Surgery

Lee S, Kim YS, Park K, Lee M, Jang JY

Purpose: In 2018, the Act to Improve Training Conditions and the Status of Medical Residents (AITR) was fully implemented in South Korea. This study aimed to investigate the effects of...
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Role of the Neutrophil-to-Lymphocyte Ratio as a Predictor of Prognosis in Cellulitis

Lee KH, Lee SY, Oh CH, Park K

  • KMID: 2532295
  • Korean J Dermatol.
  • 2022 Jul;60(6):364-370.
Background: Cellulitis is an inflammatory disease of the skin and subcutaneous tissue caused by bacterial infection and is one of the most common reasons for admission to the Department of...
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The First Case of Coniochaeta hoffmannii Fungemia and Literature Review

Hong Y, Kim D, Park K, Sung H, Kim MN

Coniochaeta hoffmannii (formerly, Lecythophora hoffmannii) is a soil-inhabiting plant pathogen in the class of Sordariomycetes. Coniochaeta species are rare and opportunistic and cause subcutaneous infections, keratitis, sinusitis, and peritonitis. Only...
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Survey of Opioid Risk Tool Among Cancer Patients Receiving Opioid Analgesics

Oh SY, Park K, Koh SJ, Kang JH, Chang MH, Lee KH

Background: The risk of opioid-related aberrant behavior (OAB) in Korean cancer patients has not been previously evaluated. The purpose of this study is to investigate the Opioid Risk Tool (ORT)...
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M2 Macrophage-Derived Concentrated Conditioned Media Significantly Improves Skin Wound Healing

Savitri C, Kwon JW, Drobyshava V, Ha SS, Park K

BACKGROUND: Macrophages, with many different phenotypes play a major role during wound healing process, secreting the cytokines crucial to angiogenesis, cell recruitment and ECM remodeling. Therefore, macrophage-derived cytokines may be...
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Choroid Plexus and Its Association of Subtypes of Delusion in Patient With Alzheimer’s Disease

Son SM, Lee YM, Park JM, Lee BD, Moon E, Jeong HJ, Suh H, Kim K, Kim HJ, Park K, Choi KU

Objective: This study examined the volume of choroid plexus across AD without delusion (AD-D), AD with paranoid delusion (AD+PD), and AD with misidentification delusion (AD+MD). Methods: This is a hospital based...
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Reduced Volume of Anterior Corpus Callosum in Alzheimer’s Disease With Psychotic Symptoms: Cross-Sectional Magnetic Resonance Imaging Study

Lee H, Lee YM, Park JM, Lee BD, Moon E, Jeong HJ, Suh H, Kim K, Kim HJ, Park K, Choi KU

Objective: Although previous studies have shown association between anterior corpus callosum (ACC) and various psychotic disorder, the effect of ACC on development on psychotic symptoms in Alzheimer’s disease (AD) is...
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CD4+/CD8+ Ratio and Growth Differentiation Factor 8 Levels in Peripheral Blood of Large Canine Males Are Useful Parameters to Build an Age Prediction Model

Lee HJ, Hong SJ, Kim SS, Kwon YY, Choi BH, Choi KM, Sheen SH, Lee MJ, Hwang SY, Park K, Joo Y, Song H, Lee CK

Purpose: To build an age prediction model, we measured CD4+ and CD8+ cells, and humoral components in canine peripheral blood. Materials and Methods: Large Belgian Malinois (BGM) and German Shepherd Dog...
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Efficacy and Safety of Mirodenafil Oro-Dispersible Film in Korean Patients with Erectile Dysfunction: A Double-Blind, Randomized, Placebo-Controlled, Parallel-Group, Multicenter, Phase IV Study

Lee SW, Son H, Lee SW, Cho KS, Moon DG, Yang DY, Chung WS, Suh JK, Park HJ, Min K, Moon KH, Park K, Park JK, Hyun JS, Yang SK

Purpose: To investigate the efficacy, safety, and tolerability of oro-dispersible film (ODF) formulation of mirodenafil 50 mg and 100 mg for the treatment of patients with erectile dysfunction (ED) in...
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Catheter ablation of outflow tract ventricular arrhythmia with intracardiac echocardiography assistance

Choi J, Park K

As the indications for catheter-based electrophysiologic procedures become more diverse and complex, accurate assessment of the anatomy of intracardiac structure has become essential for the optimal clinical outcome. Since intracardiac...
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