Korean J Gastrointest Endosc.  1998 Oct;18(5):707-712.

Reflux Esophagitis after Cure of Helicobacter pylori Infection: Report of two cases

• Seo JY
• Kim HY
• Lee JM
• Kim JS
• Yoo HS
• Lee JH
• Kim JH
• Kim YB
• Park CK
• Yoo JY

Abstract

Helicobacter pylori infection causes chronic gastritis and its well documented con- sequences are peptic ulcer disease and gastric neoplasia. As duodenal ulcer is often associated with gastroesophageal reflux disease and antral gastritis is a frequent finding in patients with reflux disease, H. pylori infection may be a common cause of both conditions. Recent studies reveal that H. pylori has no role in the pathogenesis of reflux esophagitis. Furthermore, there are some arguments on whether H. pylori infection may have a protective role in reflux esophagitis. We have experienced two cases of reflux esophagitis after cure of H. pylori infection. H. pylori eradication therapy was performed in two patients who have gastric and/or duodenal ulcer with omeprazole and two anti-biotics (clarithromycin and amoxicillin). After cure of H. pylori infection, reflux esophagitis was demonstrated in these patients by endoscopy.

Keyword

Helicobacter pylori; Reflux esophagitis; Gastric ulcer; Duodenal ulcer

MeSH Terms

Duodenal Ulcer
Endoscopy
Esophagitis, Peptic*
Gastritis
Gastroesophageal Reflux
Helicobacter pylori*
Helicobacter*
Humans
Omeprazole
Peptic Ulcer
Stomach Ulcer
Omeprazole