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Establishment of Neurotoxicity Assessment Using Microelectrode Array (MEA) with hiPSC-Derived Neurons and Evaluation of New Psychoactive Substances (NPS)

Kang Kr, Kim CY, Kim J, Ryu B, Lee SG, Baek J, Kim YJ, Lee JM, Lee Y, Choi SO, Woo DH, Park IH, Chung HM

Background and Objectives: Currently, safety pharmacological tests for the central nervous system depend on animal behavioral analysis. However, due to the subjectivity of behavioral analysis and differences between species, there...
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Clinical Utility of MicroPure US Imaging for Breast Microcalcifications

Lee H, Kim SH, Kang Bj, Lee JM

Purpose To evaluate the performance of MicroPure US imaging to detect and characterize microcalcifications. Materials and Methods A total of 171 lesions with suspicious microcalcifications seen on mammography and B-mode US...
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A case of mild CADASIL patient with a novel heterozygous NOTCH3 variant

Choi W, Hwang YH, Lee JM

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a single-gene disease caused by mutations in the neurogenic locus notch homolog protein 3 (NOTCH3) gene. The spectrum of...
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Unaltered Tonic Inhibition in the Arcuate Nucleus of Diet-induced Obese Mice

Sa M, Lee JM, Park MG, Lim J, Joseph Kim JM, Koh W, Yoon BE, Lee CJ

  • KMID: 2531118
  • Exp Neurobiol.
  • 2022 Jun;31(3):147-157.
  • doi: 10.5607/en22014
The principal inhibitory transmitter, γ-aminobutyric acid (GABA), is critical for maintaining hypothalamic homeostasis and released from neurons phasically, as well as from astrocytes tonically. Although astrocytes in the arcuate nucleus...
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Korean clinical practice guidelines for the diagnosis of hereditary hemolytic anemia

Chueh HW, Hwang SM, Shim YJ, Lee JM, Park HS, Lee JH, Nam Y, Kim N, Jung HL, Choi HS, on behalf of Korean RBC Disorder Working Party

Although the prevalence of hereditary hemolytic anemia (HHA) is relatively low in Korea, it has been gradually increasing in recent decades due to increment in the proportions of hemoglobinopathies from...
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The development and clinical efficacy of simulation training of open duct-to-mucosa pancreaticojejunostomy using pancreas and intestine silicone models

Kang JS, Sohn HJ, Choi YJ, Byun Y, Lee JM, Lee M, Kang YH, Kim HS, Han Y, Kim H, Kwon W, Jang JY

Purpose: As pancreaticojejunostomy (PJ) is a challenging anastomosis, an education program is needed to train young surgeons to perform PJ. This study evaluated the effects of simulation-based training of open...
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2021 Korean Society of Gastrointestinal Endoscopy Clinical Practice Guidelines for Endoscopic Sedation

Park HJ, Kim BW, Lee JK, Park Y, Park JM, Bae JY, Seo SY, Lee JM, Lee JH, Chon HK, Chung JW, Choi HH, Kim MH, Park DA, Jung JH, Cho JY, ESCoKSoGE

Sedation can resolve anxiety and fear in patients undergoing endoscopy. The use of sedatives has increased in Korea. Appropriate sedation is a state in which the patient feels subjectively comfortable...
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Impact of scanning strategy on the accuracy of complete-arch intraoral scans: a preliminary study on segmental scans and merge methods

Mai HY, Mai HN, Lee CH, Lee KB, Kim Sy, Lee JM, Lee KW, Lee DH

PURPOSE. This study investigated the accuracy of full-arch intraoral scans obtained by various scan strategies with the segmental scan and merge methods. MATERIALS AND METHODS. Seventy intraoral scans (seven scans per...
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2021 Korean Society of Gastrointestinal Endoscopy Clinical Practice Guidelines for Endoscopic Sedation

Park HJ, Kim BW, Lee JK, Park Y, Park JM, Bae JY, Seo SY, Lee JM, Lee JH, Chon HK, Chung JW, Choi HH, Kim MH, Park DA, Jung JH, Cho JY, Endoscopic Sedation Committee of Korean Society of Gastrointestinal Endoscopy

Sedation can resolve anxiety and fear in patients undergoing endoscopy. The use of sedatives has increased in Korea. Appropriate sedation is a state in which the patient feels subjectively comfortable...
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Evaluation of a Smart After-Care Program for Patients with Lung Cancer: A Prospective, Single-Arm Pilot Study

Yang HC, Chung SH, Yoo JS, Park B, Kim MS, Lee JM

Background: The efficacy of telemedicine among cancer survivors is uncertain. The Smart After-Care Program (SAP), which is an interactive, smartphone-based remote health monitoring system, was developed to help patients manage...
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Revascularization Strategies in Patients With ST-Segment Elevation Myocardial Infarction and Multivessel Disease: Is FFR-Guided Strategy Still Valuable?

Shin D, Rhee TM, Lee SH, Lee JM

Several studies have shown the benefit of complete revascularization (CR) over culprit-only percutaneous coronary intervention (PCI) in patients with ST-segment elevated myocardial infarction (STEMI) and multivessel disease (MVD). Nevertheless, optimal...
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Analysis of factors affecting the long-term status of adjacent and antagonistic teeth in relation to dental implants

Kim HR, Kim YG, Suh JY, Lee JM

The aim of this study is to investigate factors that affect the prognosis of adjacent and antagonistic teeth after an implant restoration. In total, 102 implant placement sites of 91...
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In vivo study for the hemostatic efficacy and foreign body reaction of a new powder-type polysaccharide hemostatic agent

Byun Y, Kim EJ, Lee A, Suh YA, Sohn HJ, Lee JM, Kang JS, Choi YJ, Han Y, Kim H, Kwon W, Jang JY

Purpose: Various hemostatic agents have been introduced in therapy as postoperative bleeding is a poor prognostic factor for postoperative outcomes. These products can be divided into those that directly promote...
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Diagnostic Performance of Spin-Echo Echo-Planar Imaging Magnetic Resonance Elastography in 3T System for Noninvasive Assessment of Hepatic Fibrosis

Kim SW, Lee JM, Park S, Joo I, Yoon JH, Chang W, Kim H

Objective: To validate the performance of 3T spin-echo echo-planar imaging (SE-EPI) magnetic resonance elastography (MRE) for staging hepatic fibrosis in a large population, using surgical specimens as the reference standard. Materials...
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Left Atrial Remodeling and Thromboembolic Risk in Patients With Atrial Fibrillation

Chung H, Lee JM

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Role of Glucose Breath Test for Small Intestinal Bacterial Overgrowth in Children and Adolescents With Functional Abdominal Pain Disorders in Korea

Lee J, Paik CN, Kim DB, Lee JM, Kim YJ, Choi SK, Cho YJ

  • KMID: 2523786
  • J Neurogastroenterol Motil.
  • 2022 Jan;28(1):78-85.
  • doi: 10.5056/jnm20231
Background/Aims Small intestinal bacterial overgrowth (SIBO) is expected in children and adolescents with functional abdominal pain disorders (FAPDs). This study is conducted to estimate the prevalence of SIBO and to investigate...
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Oncologic outcomes according to the location and status of resection margin in pancreas head cancer: role of radiation therapy in R1 resection

Sohn HJ, Kim H, Kim SJ, Lee KB, Han Y, Lee JM, Kang JS, Kwon W, Chie EK, Kim H, Jang JY

Purpose: The clinical significance of margin status in pancreatic head cancer is still controversial due to the nonstandardized definition of R status and pathologic reporting. This study aims to evaluate...
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Quantitative Evaluation of Hepatic Steatosis Using Advanced Imaging Techniques: Focusing on New Quantitative Ultrasound Techniques

Park J, Lee JM, Lee G, Jeon SK, Joo I

Nonalcoholic fatty liver disease, characterized by excessive accumulation of fat in the liver, is the most common chronic liver disease worldwide. The current standard for the detection of hepatic steatosis...
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Primary Tumor Suppression and Systemic Immune Activation of Macrophages through the Sting Pathway in Metastatic Skin Tumor

Synn CB, Kim DK, Kim JH, Byeon Y, Kim YS, Yun MR, Lee JM, Lee W, Lee EJ, Lee S, Lee YW, Lee DJ, Kim HW, Kim CG, Hong MH, Park JD, Lim SM, Pyo KH

Purpose: Agonists of the stimulator of interferon genes (STING) play a key role in activating the STING pathway by promoting the production of cytokines. In this study, we investigated the...
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Differential Prognostic Implications of Pre- and Post-Stent Fractional Flow Reserve in Patients Undergoing Percutaneous Coronary Intervention

Zhang J, Hwang D, Yang S, Kim CH, Lee JM, Nam CW, Shin ES, Doh JH, Hoshino M, Hamaya R, Kanaji Y, Murai T, Zhang JJ, Ye F, Li X, Ge Z, Chen SL, Kakuta T, Koo BK

Background and Objectives: The influence of pre-intervention coronary physiologic status on outcomes post percutaneous coronary intervention (PCI) is not well known. We sought to investigate the prognostic implications of pre-PCI...
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