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Current Status of Q Fever and the Challenge of Outbreak Preparedness in Korea: One Health Approach to Zoonoses

Cho YS, Park JH, Kim JW, Lee JJ, Youn SY, Byeon HS, Jeong HW, Kim DM, Yu SN, Yoon JW, Kwak D, Yoo HS, Lee JY, Kwon JR, Hwang KW, Heo JY

Human Q fever, a zoonosis caused by Coxiella burnetii, presents with diverse clinical manifestations ranging from mild self-limited febrile illnesses to life-threatening complications such as endocarditis or vascular infection. Although...
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Lumpy skin disease as an emerging infectious disease

Eom HJ, Lee ES, Yoo HS

Lumpy skin disease (LSD) is one of the most important emerging transboundary diseases. Recently, LSD has emerged in many countries in the northern hemisphere. The LSD virus has a huge genome...
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Multimodal Imaging Findings of Cerebral Amyloid Angiopathy Related Inflammation With Unusual Clinical Manifestation: A Case Report

Koo J, Park M, Yoo HS, Joo B, Ahn SJ, Lee JH, Ryu YH, Suh SH

Cerebral amyloid angiopathy-related inflammation (CAA-RI) is a rare encephalopathy characterized by the coexistence of a perivascular inflammatory reaction in patients with cerebral amyloid angiopathy. CAA-RI diagnosis is challenging as its...
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Cortical Thickness and Brain Glucose Metabolism in Healthy Aging

Baik K, Jeon S, Yang SJ, Na Y, Chung SJ, Yoo HS, Yun M, Lee PH, Sohn YH, Ye BS

Background and Purpose We aimed to determine the effect of demographic factors on cortical thickness and brain glucose metabolism in healthy aging subjects. Methods The following tests were performed on 71 subjects with...
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Efficacy of bivalent vaccines of porcine circovirus type 2 and Mycoplasma hyopneumoniae in specific pathogen-free pigs challenged with porcine circovirus type 2d

Lim J, Jin M, Yoon I, Yoo HS

Background: Porcine circovirus type 2 (PCV2) and Mycoplasma hyopneumoniae (MHP) are economically significant pathogens in the pig industry. The use of combined vaccines against PCV2 and MHP is one of...
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Incidence and Risk Factors of Postoperative Recovery Room Delirium in Elderly Patients after Surgery under General Anesthesia

Choi E, Seo YE, Yoo HS, Kim DY

Purpose: This study is a prospective observational study that analyzes the factors affecting and the incidence of postoperative delirium in elderly patients under general anesthesia. Methods: The study enrolled 193 elderly...
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Exposure to Secondhand Smoke and a Tobacco-Specific Carcinogen in Non-Smokers

Lee Jw, Yang W, Kim YS, Kim Y, Yoo HS, Kang HT

Background: The International Agency for Research on Cancer classifies 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) as a known carcinogen. This study aimed to investigate the association between exposure to secondhand smoke (SHS) and NNAL...
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Fumonisin B1-Induced Toxicity Was Not Exacerbated in Glutathione Peroxidase-1/Catalase Double Knock Out Mice

Yayeh T, Jeong HR, Park YS, Moon S, Sur B, Yoo HS, Oh S

Fumonisin B1 (FB1) structurally resembles sphingolipids and interferes with their metabolism leading to sphingolipid dysregulation. We questioned if FB1 could exacerbate liver or kidney toxicities in glutathione peroxidase 1 (Gpx1)...
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Protective Effect of Rice Bran Oil against β-Amyloid Protein-Induced Memory Impairment and Neuronal Death in Mice

Jang JY, Lee HK, Yoo HS, Seong YH

This study was undertaken to investigate the protective effect of rice bran oil (RBO) on amyloid β protein (Aβ) (25-35)-induced memory impairment and brain damage in an ICR mouse model....
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Comparative analysis of serological tests and fecal detection in the diagnosis of Mycobacterium avium subspecies paratuberculosis infection

Park HT, Ha S, Park HE, Shim S, Hur TY, Yoo HS

Abstract: Johne's disease (JD) caused by Mycobacterium avium subspecies paratuberculosis (MAP) is a chronic, wasting infectious disease in ruminants that causes enormous economic losses to the dairy and beef cattle...
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COVID-19 and veterinarians for one health, zoonotic- and reverse-zoonotic transmissions

Yoo HS, Yoo D

A novel coronavirus emerged in human populations and spread rapidly to cause the global coronavirus disease 2019 pandemic. Although the origin of the associated virus (severe acute respiratory syndrome coronavirus...
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Association between Olfactory Deficit and Motor and Cognitive Function in Parkinson’s Disease

Yoo HS, Chung SJ, Lee YH, Ye BS, Sohn YH, Lee PH

Objective To investigate whether baseline olfactory dysfunction in Parkinson’s disease (PD) patients is associated with baseline and longitudinal motor and cognitive function. Methods We recruited 228 drug-naïve PD patients who were...
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African swine fever: Etiology, epidemiological status in Korea, and perspective on control

Yoo D, Kim H, Lee JY, Yoo HS

African swine fever (ASF), caused by the ASF virus, a member of the Asfarviridae family, is one of the most important diseases in the swine industry due to its clinical...
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Evaluation of the immunobiological effects of a regenerative far-infrared heating system in pigs

Kim S, Park HT, Soh SH, Oh MW, Shim S, Yoo HS

Thermal conditions are an important environmental factor in maintaining healthy pigs because they affect feed intake, growth efficiency, reproduction and immune responses in pigs. RAVI, a regenerative far-infrared heating system,...
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The Influence of Body Mass Index at Diagnosis on Cognitive Decline in Parkinson's Disease

Yoo HS, Chung SJ, Lee PH, Sohn YH, Kang SY

BACKGROUND AND PURPOSE: Associations between alterations in body mass index (BMI) and cognitive function have been reported in Parkinson's disease (PD). We investigated whether the BMI at a PD diagnosis...
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Prevalence and molecular characteristics of 16s rRNA methylase gene rmtB in amikacin resistant Escherichia coli isolated from South Korea

The production of rmtB-encoded 16S rRNA methylases has emerged as a novel mechanism promoting high-level resistance toward aminoglycosides in Gram-negative bacteria. Between 2015 and 2017, 636 distinct commensal Escherichia (E.)...
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Generation and protective efficacy of a cold-adapted attenuated genotype 2b porcine epidemic diarrhea virus

Won H, Lee DU, Jang G, Noh YH, Lee SC, Choi HW, Yoon IJ, Yoo HS, Lee C

The recent emergence and re-emergence of porcine epidemic diarrhea virus (PEDV) underscore the urgent need for the development of novel, safe, and effective vaccines against the prevailing strain. In this...
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Heterogeneous Patterns of Striatal Dopamine Loss in Patients with Young- versus Old-Onset Parkinson's Disease: Impact on Clinical Features

Chung SJ, Yoo HS, Lee YH, Lee PH, Sohn YH

OBJECTIVE: Ample evidence has suggested that age at onset of Parkinson's disease (PD) is associated with heterogeneous clinical features in individuals. We hypothesized that this may be attributed to different...
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Crossed Aphasia after Right Corpus Callosum Infarction: a Case Report

Yoo HS, Kim HS

Crossed aphasia (CA) is defined as language impairment following right-hemispheric brain lesion in right-handed person. Exact mechanism responsible for CA is ambiguous, and recently several brain lesions have been proposed...
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Development of Actinobacillus pleuropneumoniae ApxI, ApxII, and ApxIII-specific ELISA methods for evaluation of vaccine efficiency

Jung M, Won H, Shin MK, Oh MW, Shim S, Yoon I, Yoo HS

Among various vaccines against Actinobacillus pleuropneumoniae, subunit vaccines using recombinant proteins of ApxI, ApxII, and ApxIII as vaccine antigens have shown good efficacy in terms of safety and protection. Therefore,...
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