J Korean Soc Pediatr Nephrol.
2014 Oct;18(2):128-131. 10.3339/jkspn.2014.18.2.128.
A Case of "Full-house" Nephropathy in a Non-lupus Patient
- Affiliations
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- 1Department of Pediatrics, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea. 19890009@kuh.ac.kr
- 2Department of Pathology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.
- KMID: 1733227
- DOI: http://doi.org/10.3339/jkspn.2014.18.2.128
Abstract
- Histopathologic evidence of "full-house" immune complex deposits is a pathognomonic feature of lupus nephritis. This report presents the case of a 12-year-old boy with persistent microscopic hematuria and proteinuria. He was diagnosed with "full-house" nephropathy based on a renal biopsy. However, there was no other clinical or biological evidence of systemic lupus erythematosus (SLE). Although the potential for isolated "full-house" nephropathy preceding SLE is unclear, such patients should be followed for clinical signs and autoantibodies of SLE. In most cases, microscopic hematuria has a good prognosis, and follow-up usually requires only regular urinalysis. However, we should be aware of isolated "full-house" nephropathy that remains asymptomatic for a long time, as few patients with no clinical signs and negative serology ultimately develop SLE.
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