Korean J Med.  2004 Feb;66(2):190-194.

A case of IgA nephropathy with systemic lupus erythematosus

• Kim HW
• Kang SW
• Choi KH
• Lee HY
• Han DS
• Kie JH
• Jeong HJ

Abstract

In systemic lupus erythematosus patients, prevalence of renal involvement is high, even in the absence of overt clinical manifestation. Lupus nephritis can usually be categorized according to the widely used WHO classification. however, clinically significant renal disease unrelated to lupus nephritis have rarely been described in patients with SLE. Especially, there has been few reported cases of IgA nephropathy with SLE since first reported in 1995, but their relationship is not apparent yet. We experienced a 72-year-old female who was admitted to our hospital due to generalized edema, arthralgia, proteinuria, microscopic hematuria. Her diagnosis of IgA nephropathy was estabilished on biopsy. At the same time, she was diagnosed as SLE. in that the serology for ANA was positive at 1:640, lupus anticoagulant and anti-cardiolipin antibody were positive, hemolytic anemia, arthritis and oral ulcer. and eventually she was diagnosed end-stage renal disease 2 months later. In conclusion, atypical glomerular lesion in SLE should raise the possibility of a non-lupus glomerulopathy, including IgA nephropathy.

Keyword

Glomerulonephritis; IgA; Lupus Erythematosus; Sytemic

MeSH Terms

Aged
Anemia, Hemolytic
Arthralgia
Arthritis
Biopsy
Classification
Diagnosis
Edema
Female
Glomerulonephritis
Glomerulonephritis, IGA*
Hematuria
Humans
Immunoglobulin A*
Kidney Failure, Chronic
Lupus Coagulation Inhibitor
Lupus Erythematosus, Systemic*
Lupus Nephritis
Oral Ulcer
Prevalence
Proteinuria
Immunoglobulin A
Lupus Coagulation Inhibitor