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New in vitro multiple cardiac ion channel screening system for preclinical Torsades de Pointes risk prediction under the Comprehensive in vitro Proarrhythmia Assay concepta

An JR, Mun SY, Jung IK, Kim KS, Kwon CH, Choi SO, Park WS

Cardiotoxicity, particularly drug-induced Torsades de Pointes (TdP), is a concern in drug safety assessment. The recent establishment of human induced pluripotent stem cell-derived cardiomyocytes (human iPSC-CMs) has become an attractive...
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Intra-Areolar Polythelia: A Case Report of a Rare Anomaly

Chun EJ, Kim JK, Yang SY, Kim KS, Kim SS, Kim CW

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Epidemiological Aspects of Imported Melioidosis in Korea and Japan, 2011 to 2020

Lee MJ, Kim KS, Lee WC, Kwon YH

Purpose: Melioidosis is a zoonosis that can infect humans or animals. The disease is caused by the bacteria Burkholderia pseudomallei, which is found in contaminated soil and water. We investigated...
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Trends of genital wart in Korea according to treatment method classification: Big data analysis of health care in 2010–2019

Kim EJ, Lee JC, Lyu DH, Choi U, Choi JB, Kim KS, Park BH, Kim S, Lee SJ, Han CH, Bae S

Purpose: The purpose of this study is to investigate disease trend of genital wart through changes in each treatment method over the past 10 years in Korea. Materials and Methods: From...
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Changes in Subjective Outcomes during the Early Period after Septoturbinoplasty

Shin GC, Kang JW, Park JH, Lee HC, Kim KS

Purpose: Septoturbinoplasty is frequently performed to correct nasal obstruction; however, there is still a lack of research on changes in nasal and nose-related symptoms early after septoturbinoplasty. Therefore, we aimed...
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Comparison of pure laparoscopic donor right posterior sectionectomy versus right hemihepatectomy: a preliminary study based on surgical outcomes of donors and recipients

Cho CW, Choi GS, Lee DH, Kim HJ, Lee DS, Rhu J, Kim JM, Joh JW, Kim KS

Background: Right posterior section (RPS) graft for living donor liver transplantation (LDLT) is an alternative graft in a live liver donor with insufficient remnant left lobe (LL) volume and portal...
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Comparison of Whole Spine Sagittal Alignment in Patients with Spinal Disease between EOS Imaging System versus Conventional Whole Spine X-ray

Jang HJ, Park JY, Kuh SU, Ha Y, Chin DK, Kim KS, Cho YE, Kim KH

Purpose: The biplanar whole body imaging system (EOS) is a new tool for measuring the whole body sagittal alignment in a limited space. This tool may affect the sagittal balance...
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Humulus japonicus attenuates LPS-and scopolamine-induced cognitive impairment in mice

Go J, Park HY, Lee DW, Maeng SY, Lee IB, Seo YJ, An JP, Oh WK, Lee CH, Kim KS

Background: Neuroinflammation plays an important role in cognitive decline and memory impairment in neurodegenerative disorders. Previously, we demonstrated that Humulus japonicus (HJ) has anti-inflammatory effects in rodent models of Alzheimer’s...
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Investigation of the Status of Laboratory Tests Conducted during Aviation Medical Examination

Jang J, Suh BS, Kwon YH, Kim KS

Purpose: The medical certification for pilots is required by the aviation safety authority based with the aviation safety act. Methods: In this study, medical examination items of the year of 2021...
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Effects of a High-Intensity Interval Physical Exercise Program on Cognition, Physical Performance, and Electroencephalogram Patterns in Korean Elderly People: A Pilot Study

Lee SM, Choi M, Chun BO, Sun K, Kim KS, Kang SW, Song HS, Moon SY

Background and Purpose: The effects of high-intensity interval training (HIIT) interventions on functional brain changes in older adults remain unclear. This preliminary study aimed to explore the effect of physical...
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PRR16/Largen Induces Epithelial-Mesenchymal Transition through the Interaction with ABI2 Leading to the Activation of ABL1 Kinase

Kang GJ, Park JH, Kim HJ, Kim EJ, Kim B, Byun HJ, Yu L, Nguyen TM, Nguyen TH, Kim KS, Huy HP, Rahman M, Kim YH, Jang JY, Park MK, Lee H, Choi CI, Lee K, Han HK, Cho J, Rho SB, Lee CH

Advanced or metastatic breast cancer affects multiple organs and is a leading cause of cancer-related death. Cancer metastasis is associated with epithelial-mesenchymal metastasis (EMT). However, the specific signals that induce...
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Deep-learning segmentation of ultrasound images for automated calculation of the hydronephrosis area to renal parenchyma ratio

Song SH, Han JH, Kim KS, Cho YA, Youn HJ, Kim YI, Kweon J

Purpose: We investigated the feasibility of measuring the hydronephrosis area to renal parenchyma (HARP) ratio from ultrasound images using a deep-learning network. Materials and Methods: The coronal renal ultrasound images of...
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Electric Scooter-Related Trauma in Korea

Choi JH, Oh SS, Kim KS, Hwang JH, Lee SY

Background: The number of users of electric scooters, which provide swift and convenient mobility options, has increased sharply over recent years as their distribution as a shared service has expanded....
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Changes in Stress, Occupational Stress, and Subjective Health Problems of Novice Female Nurses: Secondary Data Analysis

Choi JY, Ki JS, Kim KS, Kim S, Choi-kwon S

Purpose: This study aimed to examine the changes in stress, occupational stress, and subjective health problems of novice female nurses within the first 18 months of work. Methods: This was...
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Association of Maternal Hypertensive Disorders During Pregnancy With Severe Bronchopulmonary Dysplasia: A Systematic Review and Meta-Analysis

Lim G, Kim YJ, Chung S, Park YM, Kim KS, Park HW

Background: This meta-analysis was performed to examine the association between maternal hypertension during pregnancy (HDP) and neonatal bronchopulmonary dysplasia (BPD). Methods: We systematically searched PubMed, EMBASE, the Cochrane Library, and the...
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Loss of EMP2 Inhibits Melanogenesis of MNT1 Melanoma Cells via Regulation of TRP-2

Enkhtaivan E, Kim HJ, Kim B, Byun HJ, Yu L, Nguyen TM, Nguyen TH, Do PA, Kim EJ, Kim KS, Huy HP, Rahman M, Jang JY, Rho SB, Lee H, Kang GJ, Park MK, Kim NH, Choi CI, Lee K, Han HK, Cho J, Lee AY, Lee CH

Melanogenesis is the production of melanin from tyrosine by a series of enzyme-catalyzed reactions, in which tyrosinase and DOPA oxidase play key roles. The melanin content in the skin determines...
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Pulmonary vein aneurysm in a New Zealand White rabbit: a case report

Kim JM, Woo CG, Kim SH, Jeong ES, Kim KS, Kang BC

Background: Pulmonary venous aneurysm (PVA) is a rare condition characterized by aneurysmal dilatation of the pulmonary vein in humans. The diagnosis is incidental usually as there are no clinical symptoms....
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Preventive effect of biodegradable stents on biliary stricture and fibrosis after biliary anastomosis in a porcine model

Kwon CI, Choi SH, Kim KS, Moon JP, Park S, Jeon J, Kim G, Jang JY, Sung MJ, Ko KH, Son JS

Purpose: The current drain tubes for preventing surgically biliary anastomotic stricture are not naturally and easily removed. If a drain tube using biodegradable material is easily available and the degradation...
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The change of antibiotic susceptibility in febrile urinary tract infection in childhood and adolescence during the last decade

Choi U, Kim E, Lyu DH, Kim KS, Park BH, Chung H, Han CH, Bae S

Purpose: The purpose of this study was to clarify the pattern of antibiotic resistance in pediatric urinary tract infections (UTIs). Materials and Methods: We analyzed the data of entire urine culture...
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Effect of Training Types Using Recumbent Cycle Ergometer on Ankle Strength in Healthy Male Subjects

Ryu HY, Jeon IC, Kim KS

Purpose: The purpose of this study was to investigate the exercise effect of two types of training with a recumbent cycle ergometer on ankle muscle strength (dorsiflexor strength, DFS; dorsiflexor...
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