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Diagnostic conundrums of schwannomas: two cases highlighting morphological extremes and diagnostic challenges in biopsy specimens of soft tissue tumors

Kim C, Chung YG, Jung CK

Schwannomas are benign, slow-growing peripheral nerve sheath tumors commonly occurring in the head, neck, and flexor regions of the extremities. Although most schwannomas are easily diagnosable, their variable morphology can...
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Monitoring the Outcomes of Systemic Chemotherapy Including Immune Checkpoint Inhibitor for HER2-Positive Metastatic Gastric Cancer by Liquid Biopsy

Jung SH, Lee Ck, Kwon WS, Yun S, Jung M, Kim HS, Chung HC, Chung YJ, Rha SY

Purpose: For precision medicine, exploration and monitoring of molecular biomarkers are essential. However, in advanced gastric cancer (GC) with visceral lesions, an invasive procedure cannot be performed repeatedly for the...
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Noninvasive Testing for Colorectal Cancer Screening: Where Are We Now?

Chun J, Kim JH, Youn YH, Park H

Colorectal cancer (CRC) is one of the most prevalent cancers and is the leading cause of cancerrelated mortality worldwide. Based on the current screening guidelines by the American Cancer Society...
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Sample Collection Methods in Upper Gastrointestinal Research

Yang HJ, Seo SI, Lee J, Huh CW, Kim JS, Park JC, Kim H, Shin H, Shin CM, Park CH, Lee SK, the Research Management Committee, Korean College of Helicobacter and Upper Gastrointestinal Researc

In recent years, significant translational research advances have been made in the upper gastrointestinal (GI) research field. Endoscopic evaluation is a reasonable option for acquiring upper GI tissue for research...
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The Usefulness of Ultrasound-Guided Core Needle Biopsy Compared to Fine Needle Aspiration in Pre-Operative Diagnosis of Cystic-Predominant Parotid Tumors

Cho YJ, Jo YR, Hong HJ, Lee HR

Background and Objectives Accurate preoperative prediction of final histopathologic diagnosis is essential in parotid tumor management, which also includes surgical planning. As a preoperative diagnostic examination for parotid tumors, the...
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The Role of Magnetic Resonance Imaging (MRI) and MRI-Targeted Biopsy for Active Surveillance

Jeong CW

This review explores the role of magnetic resonance imaging (MRI) and MRI-targeted biopsies in the selection and monitoring of men with low-risk prostate cancer (PCa) who are on active surveillance...
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Reevaluating diagnostic categories and associated malignancy risks in thyroid core needle biopsy

Jung CK

As the application of core needle biopsy (CNB) in evaluating thyroid nodules rises in clinical practice, the 2023 Korean Thyroid Association Management Guidelines for Patients with Thyroid Nodules have officially...
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Trends of axillary surgery in breast cancer patients with axillary lymph node metastasis: a comprehensive single-center retrospective study

Kim YJ, Kim HJ, Chung SY, Lee SK, Chae BJ, Yu J, Lee JE, Kim SW, Nam SJ, Ryu JM

Purpose: Based on the results of previous trials, de-escalation of axillary surgery after neoadjuvant chemotherapy (NAC) has increased in patients with axillary lymph node (ALN) metastasis at presentation. This study...
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Renal Doppler ultrasonography for predicting non-diabetic kidney disease in patients with diabetes

Jung SI, Moon MH, Sung CK, Lee MS, Park JH, Oh S

Purpose: This study was conducted to assess the role of renal Doppler ultrasonography (US) in predicting non-diabetic kidney disease (NDKD) in patients with diabetes, using histologic findings as the reference...
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Letter regarding β€œIs liver biopsy essential to identifying the immune tolerant phase of chronic hepatitis B?”

Emiroglu HH

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Impact of Ultrasonographic Findings on Cancer Detection Rate during Magnetic Resonance Image/ Ultrasonography Fusion-Targeted Prostate Biopsy

Nam JK, Song WH, Lee SS, Lee HJ, Kim TU, Park SW

Purpose To evaluate the impact of paired transrectal ultrasonography (TRUS) findings of index lesions identified by multiparametric magnetic resonance imaging (mpMRI) on the detection rate of clinically significant prostate cancer (csPCa,...
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Circulating Tumor DNA Dynamics and Treatment Outcome of Regorafenib in Metastatic Colorectal Cancer

Lee DW, Lim Y, Kim HP, Kim SY, Roh H, Kang JK, Lee K, Kim MJ, Ryoo SB, Park JW, Jeong SY, Park KJ, Kang GH, Han SW, Kim TY

Purpose Circulating tumor DNA (ctDNA) is emerging as a valuable non-invasive tool to identify tumor heterogeneity and tumor burden. This study investigated ctDNA dynamics in metastatic colorectal cancer patients treated...
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Efficacy of Olaparib in Treatment-Refractory, Metastatic Breast Cancer with Uncommon Somatic BRCA Mutations Detected in Circulating Tumor DNA

Yoon JK, Ahn J, Kim S, Kim HP, Kang Jk, Bang D, Lim Y, Kim TY

Poly(ADP-ribose) polymerase inhibitors have been shown dramatic responses in patients with BRCAness. However, clinical studies have been limited to breast cancer patients with germline mutations. Here, we describe a patient...
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Detection of Glioma-Related Hotspot Mutations Through Sequencing of Cerebrospinal Fluid (CSF)-Derived Circulating Tumor DNA: A Pilot Study on CSF-Based Liquid Biopsy for Primary Spinal Cord Astrocytoma

Cheng L, Duan W, Guan J, Wang K, Liu Z, Wang X, Wang Z, Wu H, Chen Z, Jian F

Objective: Although cerebrospinal fluid (CSF)-based liquid biopsy was proved to be practical in molecular analysis of intracranial gliomas, liquid biopsy of primary intramedullary astrocytoma was rarely reported. Given the distinct...
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Solitary fibrofolliculoma on the nasal septum: a case report

Chi YH, Woo JY, Koh TK, Koo SK, Son H

Fibrofolliculoma is a benign, perifollicular, connective tissue tumor that usually arises in the form of multiple lesions; it is rarely seen as a solitary lesion. The lesions are clinically asymptomatic,...
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Primary Cutaneous Mucinous Eccrine Carcinoma Arising in the Lower Eyelid: A Rare Case Report

Yong MJ, Shin HK, Jung KY, Jang TJ, Lee JH

Mucinous Eccrine carcinoma (MEC) is a rare malignant tumor related to the eccrine sweat gland and is commonly located on the face, especially around the eyelids and scalp. Most of...
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A Case of Intra-thyroidal Schwannoma Diagnosed by Preoperative Core Needle Biopsy

Choi DG, Kim YO, Jung MJ, Lee HS

Schwannoma is a slow growing benign tumor that can occur anywhere in our body. About 25~45% cases of schwannomas occur in the head and neck, but intra-thyroidal schwannomas are very...
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Effectiveness of fosfomycin-based antimicrobial prophylaxis for transrectal ultrasound-guided prostate biopsy: A Korean multicenter study

Lim DG, Jung SI, Hwang EC, Kim TH, Bae S, Huh JS, Lee SJ, Chung H, Choi H

Purpose: Recent studies have highlighted increasing infectious complications due to fluoroquinolone (FQ)-resistant organisms in men undergoing transrectal ultrasound-guided prostate biopsy (TRUSPB). This study investigated whether fosfomycin (FM)-based antibiotic prophylaxis reduces...
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Effect of constipation on acute urinary retention following transrectal prostate biopsy

Sahin C, Sinanoglu O, Karaca Y, Yuksel A, Kucuk EV, Sarica K, Erdogan E

Purpose: To evaluate the possible effect of constipation on the acute urinary retention (AUR) after transrectal ultrasound-guided prostate biopsy (TRUS PB). Materials and Methods: A total of 1,167 patients with prostate-specific...
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Expression of specific microRNAs in tissue and plasma in colorectal cancer

Fellizar A, Refuerzo V, Ramos JD, Albano PM

Background: MicroRNAs (miRNA/miR) play significant roles in the regulation of cell differentiation, cell cycle progression, and apoptosis. They become dysregulated during carcinogenesis and are eventually released into the circulation, enabling...
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