J Korean Rheum Assoc.
2003 Mar;10(1):39-44.
The Secondary Amyloidosis in Rheumatic Diseases
- Affiliations
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- 1The Hospital for Rheumatic Diseases, Hanyang University Medical Center, Seoul, Korea.
- 2Department of Internal Medicine, SoonChunHyang University Bucheon Hospital, Bucheon, Korea.
Abstract
OBJECTIVE
To study the clinical features and outcomes in 10 cases of secondary amyloidosis with rheumatic disease.
METHODS
The secondary amyloidosis associated with rheumatic disease was studied clinically in 10 patients (4 men and 6 women), who have suspicious tissue dysfunction. The diagnosis of amyloidosis was established by histological examination of biopsy materials. We evaluated them by medical record review; clinical features at onset, organ involvement, cause of death.
RESULTS
The mean age and mean duration of rheumatic disease were 52.9+/-17.27 years and 10.9+/-10.33 years respectively. The common initial clinical features were generalized edema, diarrhea and abdominal pain. The mainly involved organs were kidney and colon. Causes of death were DIC due to sepsis and renal failure.
CONCLUSION
Renal and gastrointestinal symptoms are cardinal features of secondary amyloidosis with rheumatic disease in Korea.
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