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Changing Epidemiology of Pathogenic Bacteria Over the Past 20 Years in Korea

Bae MH, Kim MS, Kim TS, Kim S, Yong D, Ha GY, Ryoo NH, Uh Y, Shin JH, Lee HS, Sohn YH, Shin S, Kim MN

Background: The epidemiology of pathogenic bacteria varies according to the socioeconomic status and antimicrobial resistance status. However, longitudinal epidemiological studies to evaluate the changes in species distribution and antimicrobial susceptibility...
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Effects of retinoid-loaded hyaluronic acid nanomicelles on vaginal epithelium in a murine menopause model

Kim T, Chung HS, Lee HS, Uthaman S, Park IK, Park K

Purpose: This study aimed to develop hyaluronic acid (HA)-based, retinoic acid (RA)-containing nanomicelles and to investigate the effects of these newly developed nanomicelles on regeneration of the vaginal epithelium and...
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Impact of Body Mass Index on Survival Depending on Sex in 14,688 Patients with Gastric Cancer in a Tertiary Hospital in South Korea

Jo HH, Kim N, Jang J, Choi Y, Park J, Park YM, Ahn S, Yoon H, Shin CM, Park YS, Lee DH, Oh HJ, Lee HS, Park YS, Ahn SH, Suh YS, Park DJ, Kim HH, Kim JW, Kim JW, Lee KW, Chang W, Park JH, Lee YJ, Lee KH, Kim YH

Background/Aims: The incidence and prognosis of gastric cancer (GC) shows sex difference. This study aimed to evaluate the effect of body mass index (BMI) on GC survival depending on sex. Methods: The...
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Clinical Outcomes of Endoscope-Assisted Pulmonary Endarterectomy for Chronic Thromboembolic Pulmonary Hypertension

Kim HH, Lee HS, Kim HS, Youn YN

Purpose: Pulmonary thromboembolism is a potentially life-threatening condition in patients with heart disease; however, limited studies discussing long-term outcomes exist. This study aimed to investigate the long-term outcomes of pulmonary...
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Magnesium intake and dietary sources among Koreans: findings from the Korea National Health and Nutrition Examination Survey 2016–2019

Shim JS, Kim KN, Lee JS, Yoon MO, Lee HS

BACKGROUND/OBJECTIVES: Magnesium is an essential nutrient for human health. However, inadequate intake is commonly reported worldwide. Along with reduced consumption of vegetables and fruits and increased consumption of refined or processed...
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Revised Clinical Practice Guidelines of the Korean Pancreatobiliary Association for Acute Pancreatitis

Lee SH, Choe JW, Cheon YK, Choi M, Jung MK, Jang DK, Jo JH, Lee JM, Kim EJ, Han SY, Choi YH, Seo HI, Lee DH, Lee HS

Acute pancreatitis can range from a mild, self-limiting disease requiring no more than supportive care, to severe disease with life-threatening complications. With the goal of providing a recommendation framework for...
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Allergen sensitization trajectories in children with respiratory and allergic diseases

Jo SW, Jeon S, Lee HS, Kim HM, No YY, Park MR, Jung JH, Kim SY, Kim JD, Kim MJ, Lee YJ, Kim KW, Sohn MH, Kim YH

Purpose: There is a lack of a report about the trajectories of allergen sensitization, although it is important to understand the change of allergen sensitization to manage allergic disease. This...
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A Standardized Pathology Report for Gastric Cancer: 2nd Edition

Park YS, Kook MC, Kim Bh, Lee HS, Kang DW, Gu MJ, Shin OR, Choi Y, Lee W, Kim H, Song IH, Kim KM, Kim HS, Kang G, Park DY, Jin SY, Kim JM, Choi YJ, Chang HK, Ahn S, Chang MS, Han SH, Kwak Y, Seo AN, Lee SH, Cho MY, The Gastrointestinal Pathology Study Group of the Korean Society of Pathologists

The first edition of ‘A Standardized Pathology Report for Gastric Cancer’ was initiated by the Gastrointestinal Pathology Study Group of the Korean Society of Pathologists and published 17 years ago....
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Machine-Learning Model for the Prediction of Hypoxaemia during Endoscopic Retrograde Cholangiopancreatography under Monitored Anaesthesia Care

Kang H, Lee B, Jo JH, Lee HS, Park JY, Bang S, Park SW, Song SY, Park J, Shim H, Lee JH, Yang E, Kim EH, Kim KJ, Kim MS, Chung MJ

Purpose: Hypoxaemia is a significant adverse event during endoscopic retrograde cholangiopancreatography (ERCP) under monitored anaesthesia care (MAC); however, no model has been developed to predict hypoxaemia. We aimed to develop...
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Loganin Prevents Hepatic Steatosis by Blocking NLRP3 Inflammasome Activation

Jang JH, Yang G, Seok JK, Kang HC, Cho YY, Lee HS, Lee JY

Activation of the NLRP3 inflammasome is a necessary process to induce fibrosis in nonalcoholic fatty liver disease (NAFLD). Nonalcoholic steatohepatitis (NASH) is a kind of NAFLD that encompasses the spectrum...
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A Malignant Tumor in the Calf Muscles Misdiagnosed as a Myofascial Trigger Point

Lee HJ, Lee HS, Beom J

Tumors are rare causes of calf pain and usually present insidiously. A 69-year-old woman developed sudden severe pain and a hard palpable mass in her left calf that persisted for...
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The Study on the Sleep Duration of Gastric Cancer Survivor in Korean Adults: The 7th (2016–2018) Korea National Health and Nutrition Examination Survey

Joo EH, Ryou IS, Lee SW, Lee HS, Shim KW, Sohn YJ

Background: The relationship between cancer survival and sleep duration remains inconsistent, especially for gastric cancer. This study investigated the relationship between sleep duration and gastric cancer survival among Korean adults. Methods:...
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Determining the Optimal Cut-off Point According to the Outcome Variables Using R

Yang J, Lee HS

Clinical research ultimately aimed to promptly diagnose and prevent diseases through precise biomarker development. Finding the optimal cut-off point of a regularly measured biomarker can help its interpretation and ultimately...
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Reactogenicity and Immunogenicity of the ChAdOx1 nCOV-19 Coronavirus Disease 2019 Vaccine in South Korean Healthcare Workers

Hyun J, Park Y, Song YG, Han SH, Park SY, Kim SH, Park JS, Jeon SY, Lee HS, Lee KH

Purpose: The association between reactogenicity and immunogenicity of the ChAdOx1 nCOV-19 is controversial. We aimed to evaluate this association among South Korean healthcare workers (HCWs). Materials and Methods: Participants received two...
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Immunostimulatory activity of hydrolyzed and fermented Platycodon grandiflorum extract occurs via the MAPK and NF-κB signaling pathway in RAW 264.7 cells

Jung JI, Lee HS, Kim SM, Kim S, Lim J, Woo M, Kim EJ

BACKGROUND/OBJECTIVES: Platycodon grandiflorum (PG) has long been known as a medicinal herb effective in various diseases, including bronchitis and asthma, but is still more widely used for food. Fermentation...
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Intraoperative Neuromonitoring with Adhesive Skin Electrodes for a Patient with Papillary Thyroid Carcinoma with Lateral Neck Metastasis: a Case Report

Kim YJ, Lee DW, Lee KD, Lee HS

Intraoperative neuromonitoring (IONM) of recurrent laryngeal nerve during thyroidectomy has been widely applied worldwide. Adhesive skin electrodes have been recently suggested as an alternative to applying electromyography (EMG) tube during...
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A Case of Papillary Thyroid Carcinoma Accompanied by Zenker’s Diverticulum: Considerations for Surgery

Lee DW, Lee HS

Zenker’s diverticulum is rarely known to be an impediment to the diagnosis and surgical procedure for thyroid disease. In this report, we discuss a rare case of pre-operative diagnosis of...
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Clinical outcomes and implications of pretransplant history of malignancy in heart transplant recipient

Kim D, Youn JC, Kim JJ, Kim KA, Kim IC, Lee HS, Choi JO, Jeon ES, Kobashigawa JA

Background: The number of patients with prior malignancy needing heart transplant (HTx) is increasing; however, detailed clinical characteristics and long-term clinical outcomes of these patients are largely unknown. We sought...
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Neutrophil Recruitment in Arterial Thrombus and Characteristics of Stroke Patients with Neutrophil-Rich Thrombus

Cha MJ, Ha J, Lee H, Kwon I, Kim S, Kim YD, Nam HS, Lee HS, Song TJ, Choi HJ, Heo JH

Purpose: Neutrophils contribute to thrombosis. However, there is limited information on the temporal course of neutrophil recruitment in thrombosis, the contribution of neutrophils to thrombus growth, and the characteristics of...
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Clinical and Genetic Characteristics of Korean Patients Diagnosed with Chronic Enteropathy Associated with SLCO2A1 Gene: A KASID Multicenter Study

Hong HS, Baek J, Park JC, Lee HS, Park D, Yoon AR, Park SJ, Hong SN, Koh SJ, Lee CK, Lee BI, Hwang SW, Park SH, Myung SJ, Yang SK, Song K, Ye BD, obotIRGotKAftSoID

Background/Aims: Chronic enteropathy associated with SLCO2A1 gene (CEAS), an inherited disease characterized by nonspecific intestinal ulcers, has emerged in the Japanese population via loss-of-function mutations in the SLCO2A1 gene. We...
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