Korean J Pathol.
2011 Jul;45(Suppl 1):S66-S69. 10.4132/KoreanJPathol.2011.45.S1.S66.
Brucella Prostatitis: A First Case Report Diagnosed in Korea
- Affiliations
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- 1Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.
- 2Department of Pathology, Keimyung University School of Medicine, Daegu, Korea. msc@dsmc.or.kr
- KMID: 1443666
- DOI: http://doi.org/10.4132/KoreanJPathol.2011.45.S1.S66
Abstract
- Brucellosis is a zoonosis caused by several species of Brucella. Brucellosis is usually an acute or sub-acute febrile illness that histologically develops granulomatous inflammation. Brucella prostatitis is a very rare complication and is usually accompanied by epididymo-orchitis. We now report a case of histologically proven granulomatous prostatitis due to Brucella without clinical evidence of epididymo-orchitis. A 61-year-old farmer presented with myalgia, low back pain, and fever. A needle biopsy of the prostate was performed due to symptoms of urinary frequency and high prostate specific antigen levels (17.3 ng/mL). Histologically, the prostate showed granulomatous inflammation without caseous necrosis. Polymerase chain reaction (PCR) studies of blood and prostatic tissue for Brucella were positive, while a PCR study for Mycobacterium tuberculosis was negative. The patient was treated with doxycycline and rifampin. A possibility of Brucella prostatitis should be considered in the differential diagnosis of granulomatous prostatitis or prostatitis of unknown origin associated with or without epididymo-orchitis.
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