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BRCA1-associated protein 1 expression and prognostic role in prostate adenocarcinoma

Oh H, Lee YJ, Kang SG, Ahn B, Kim E, Chae YS, Lee Y, Lee JH, Kim CH

PURPOSE: As prostate cancer (PCa) is the second most commonly diagnosed cancer worldwide, finding novel markers for prognosis is crucial. BRCA1-associated protein 1 (BAP-1), a nuclear-localized deubiquitinating enzyme, has been...
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Targeted next-generation sequencing for locally advanced prostate cancer in the Korean population

Suh J, Jeong CW, Choi S, Ku JH, Kim HH, Kim KS, Kwak C

PURPOSE: This study aimed to evaluate the feasibility of pan-cancer panel analysis for locally advanced prostate cancer in the Korean population. MATERIALS AND METHODS: We analyzed 20 patients with locally advanced...
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Preoperative prostate health index and %p2PSA as the significant biomarkers of postoperative pathological outcomes of prostate cancer in Korean males: A prospective multi-institutional study

Park H, Lee SW, Song G, Kang TW, Jung JH, Chung HC, Kim SJ, Park JY, Shin TY, Kim JH

PURPOSE: To evaluate the clinical utility of percentage of serum prostate-specific antigen (proPSA) to free PSA (%p2PSA) and the prostate health index (PHI) for predicting aggressive pathological outcomes of radical...
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Comparison of prostate cancer detection rates of various prostate biopsy methods for patients with prostate-specific antigen levels of < 10.0 ng/mL in real-world practice

Oh KT, Koo KC, Chung BH, Lee KS

PURPOSE: Several strategies of prostate biopsy (PBx) have been introduced to improve prostate cancer (PCa) detection rates. However, studies comparing cancer detection rates (CDRs) according to biopsy methods in real-world...
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Testosterone Replacement Therapy for Patients with Hypogonadism after High Dose-Rate Brachytherapy for High-Risk Prostate Cancer: A Report of Six Cases and Literature Review

Kadomoto S, Shigehara , Iwamoto H, Yaegashi H, Izumi K, Kadono Y, Mizokami A

We had six cases of patients who were treated with long-term testosterone replacement therapy (TRT) after high dose-rate (HDR) brachytherapy and androgen deprivation therapy for high-risk prostate cancer. All patients...
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Performance and Impact of Prostate Specific Membrane Antigen-Based Diagnostics in the Management of Men with Biochemical Recurrence of Prostate Cancer and its Role in Salvage Lymph Node Dissection

Krimphove , Theissen L, Cole AP, Preisser F, Mandel PC, Chun FK

Up to 50% of patients initially treated for prostate cancer in a curative intent experience biochemical recurrence, possibly requiring adjuvant treatment. However, salvage treatment decisions, such as lymph node dissection...
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Prostate Carcinosarcoma Developing After Combined Pelvic External Beam Radiation Therapy and Androgen Deprivation Therapy

Kim YJ

Carcinosarcoma of the prostate is a very rare disease, which consists of carcinomatous and sarcomatous components. The prognosis of patients with prostatic carcinosarcoma is poor. An 80-year-old man who had...
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Impact of Bladder Neck Stiffness on Lower Urinary Tract Symptoms in Patient With Benign Prostatic Hyperplasia

Kwon JK, Jung HD, Cho KS

PURPOSE: We evaluated the impact of bladder neck stiffness on lower urinary tract symptoms in the patient with benign prostatic hyperplasia using elastography. MATERIALS AND METHODS: A total of 384 patients...
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History of Diabetes Mellitus and Risk of Prostate Cancer: A Meta-Epidemiological Study of Population-Based Cohort Studies in East Asian Men

Bae JM

PURPOSE: Seven quantitative systematic reviews previously published showed that the direction of risk of prostate cancer associated with history of diabetes mellitus was in the opposite. The aim of this...
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Performance Evaluation of the Total Prostate- Specific Antigen (PSA), Free PSA, and [–2]proPSA Assay for Calculation of the Prostate Health Index Using the UniCel DxI 800 Analyzer

Choi WK, Kim HK, Lee W, Chun S, Min WK

BACKGROUND: Prostate-specific antigen (PSA) is widely used as a tumor marker of prostate cancer, but it is not specific for cancer. Numerous efforts have been made to find another tumor...
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Safety Profile and Therapeutic Efficacy of One Cycle of Lu177-PSMA in End-Stage Metastatic Castration-Resistant Prostate Cancer Patients with Low Performance Status

Gupta M, Choudhury , Rawal S, Karthikeyan G, Talwar V, Dutta KD, Singh A

PURPOSE: The aim of this study was to evaluate safety and therapeutic efficacy of lutetium 177 prostate-specific membrane antigen (Lu-177-PSMA) in metastatic castration-resistant prostate cancer (mCRPC) patients with low performance...
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Cribriform Pattern at the Surgical Margin is Highly Predictive of Biochemical Recurrence in Patients Undergoing Radical Prostatectomy

Kim KH, Ku JY, Lee CH, Park WY, Ha HK

OBJECTIVES: We investigated the relationship between cribriform patterns and biochemical recurrence in patients with positive surgical margins after radical prostatectomy. METHODS: This study was based on radical prostatectomy specimens obtained from...
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Clinical Course of the Benign Prostate Hyplasia Patients during the Intermittent Use of 5-Alpha Reductase Inhibitors

Choi K, Kim B, Cho IC, Min SK

PURPOSE: 5-Alpha reductase inhibitors (5ARI), inhibit the conversion of testosterone to dihydrotestosterone, which is essential in prostate hyperplasia, and decreases the prostate volume directly. On the other hand, 5ARI have...
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The clinical utility of transperineal template-guided saturation prostate biopsy for risk stratification after transrectal ultrasound-guided biopsy

Song W, Kang M, Jeong BC, Seo SI, Jeon SS, Lee HM, Jeon HG

PURPOSE: To investigate the clinical utility of transperineal template-guided saturation prostate biopsy (TPB) for risk stratification after transrectal ultrasound (TRUS)-guided biopsy. MATERIALS AND METHODS: We retrospectively reviewed 155 patients who underwent...
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The association of family history of prostate cancer with the diagnosis of clinically significant prostate cancer in Korean population

Park JS, Koo KC, Chung BH, Lee KS

PURPOSE: The impact of family history on the diagnosis of the prostate cancer among Asian population remains controversial. We evaluated whether a positive family history of the prostate cancer in...
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Prognostic significance of lymphovascular invasion in patients with prostate cancer treated with postoperative radiotherapy

Jeong JU, Nam TK, Song JY, Yoon MS, Ahn SJ, Chung WK, Cho IJ, Kim YH, Cho SH, Jung SI, Kwon DD

PURPOSE: To determine prognostic significance of lymphovascular invasion (LVI) in prostate cancer patients who underwent adjuvant or salvage postoperative radiotherapy (PORT) after radical prostatectomy (RP) MATERIALS AND METHODS: A total of...
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Albizzia julibrissin Suppresses Testosterone-induced Benign Prostatic Hyperplasia by Regulating 5α-Reductase Type 2 – Androgen Receptor Pathway

Hong GL, Kim HT, Park SR, Lee NH, Ryu KA, Kim TW, Song GY, Jung JY

Albizzia julibrissin (AJ) is an herbal medicine that shows low toxicity, promotes promoting blood circulation and mitigates the inflammation and has mild side effects. Benign prostate hyperplasia (BPH) is one...
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Machine Learning Approaches for the Prediction of Prostate Cancer according to Age and the Prostate-Specific Antigen Level

Lee J, Yang SW, Lee S, Hyon YK, Kim J, Jin L, Lee JY, Park JM, Ha T, Shin JH, Lim JS, Na YG, Song KH

PURPOSE: The aim of this study was to evaluate the applicability of machine learning methods that combine data on age and prostate-specific antigen (PSA) levels for predicting prostate cancer. MATERIALS AND...
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Rectal Invasion by Prostatic Adenocarcinoma That Was Initially Diagnosed in a Rectal Polyp on Colonoscopy

Yoon G, Han MH, Seo AN

Despite anatomical proximity, prostatic adenocarcinoma with rectal invasion is extremely rare. We present a case of rectal invasion by prostatic adenocarcinoma that was initially diagnosed from a rectal polyp biopsied...
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Retrospective Study of the Significant Predictive Role of Inflammatory Degree in Initial and Repeat Prostate Biopsy Specimens for Detecting Prostate Cancer

Kim SH, Park B, Joung JY, Chung J, Seo HK, Lee KH, Park WS

PURPOSE: The purpose of this study was to determine whether histologic inflammation (HI) in initial and repeat prostate biopsy specimens was significantly associated with the detection of prostate cancer. MATERIALS AND...
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