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Gemcitabine and Erlotinib with or without Oxaliplatin in Previously Untreated Advanced Pancreatic Cancer: A Randomized Phase II Trial

Lim SH, Yun J, Lee MY, Kim HJ, Kim KH, Kim SH, Lee SC, Bae SB, Kim CK, Lee N, Lee KT, Park SK, Lee YN, Moon JH

Purpose: Erlotinib has been the only targeted agent to show significantly improved outcomes in pancreatic adenocarcinoma when combined with gemcitabine. We aimed to evaluate whether the addition of oxaliplatin to...
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Generation of a recombinant rabies virus expressing green fluorescent protein for a virus neutralization antibody assay

Yang DK, Kim HH, Park YR, Yoo JY, Park Y, Park J, Hyun BH

Background: Fluorescent antibody virus neutralization (FAVN) test is a standard assay for quantifying rabies virus-neutralizing antibody (VNA) in serum. However, a safer rabies virus (RABV) should be used in the...
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Incidence and Risk of Venous Thromboembolism in Bisphosphonates and Selective Estrogen Receptor Modulators Treatment in Korea

Park SY, Kim SH, Kim TY, Lee YK, Ha YC, Jang S, Ahn SH, Kim HY

Background: Selective estrogen receptor modulators (SERMs) were associated with an increased risk of venous thromboembolism (VTE) due to the estrogen effect. In this study, we investigated the effect of SERMs...
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Gastrointestinal and Nongastrointestinal Complications of Esophagogastroduodenoscopy and Colonoscopy in the Real World: A Nationwide Standard Cohort Using the Common Data Model Database

Kim HI, Yoon JY, Kwak MS, Cha JM

Background/Aims: The global trend of an expanding aged population has increased concerns about complications correlated with gastrointestinal (GI) endoscopy in elderly patients; however, there have been few reports published on...
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A case of canine blepharoconjunctivitis associated with atopic dermatitis

Kim Y, Kim HJ, Kim JH, Lee JH, Kim S, Kim SE, Kim T, Kim HJ

An 8-year-old, spayed female Maltese dog was presented with a one-month history of erythema, swelling and alopecia of periocular region with pruritus. The skin lesions were first detected at the...
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A Mixed Method Study for Exploring the Difficulties in End-of-Life Care and End-of-Life Care Competency in Nurses Who Take Care of Cancer Patients

Kim LH, Kim SY, Kim S, Kim HA, Yang HJ, Lee KM, Lee SY, Lee KH, Kim JH

Purpose: This study investigated the difficulties in end-of-life care and end-of-life care competency in nurses who take care of cancer patients. Methods: In the mixed method, a structured questionnaire on...
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Fulminant Disseminating Fatal Granulomatous Amebic Encephalitis: The First Case Report in an Immunocompetent Patient in South Korea

Lee JY, Yu IK, Kim SM, Kim JH, Kim HY

Central nervous system infections caused by free-living amoeba are very rare, but often fatal. The typical image findings of amebic meningoencephalitis are non-specific, showing ring-like enhancement. We report the first...
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Effect of Equal Ratio Ventilation on Respiratory Mechanics and Oxygenation During Volume-Controlled Ventilation in Pediatric Patients

Kim HY, Ham SY, Kim EJ, Yoon HJ, Choi SY, Koo BN

Purpose: Children have few small alveoli, which reduce lung compliance; in contrast, their cartilaginous rib cage makes their chest wall highly compliant. This combination promotes lung collapse. Prolonged inspiratory to...
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Ankle Fractures in Children: Classification and Treatment

Kim HY, Cha YH, Kim WS, Choy WS

Pediatric ankle fractures are defined as damage to the metaphysis, epiphyseal plate, and epiphysis of the distal tibia and fibula. Although the injury mechanism could be similar, the fracture patterns...
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Clinical Nutrition

Kim HN

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Intractable Coronary Spasm Requiring Percutaneous Coronary Intervention after Coronary Artery Bypass Grafting in a Patient with Moyamoya Disease

Kim HA, Kim YS, Kim WS

Moyamoya disease (MMD) is characterized by progressive steno-occlusive lesions of the distal or proximal branch of the internal carotid arteries, and cerebrovascular symptoms are its major complications. Extracranial vascular involvement...
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Health-related Quality of Life Outcomes of Adalimumab for Patients With Rheumatoid Arthritis in Korea

Lee Ms, Lee CH, Lee HS, Sung YK, Choi JR, Park K, Lim MK, Choi BY, Kim HA, Choi SW, Lee Y, Yoo WH

Objective: Rheumatoid arthritis (RA) is a chronic, progressive, autoimmune disorder that impairs patients’ overall health-related quality of life (HRQOL). In this study, we evaluated the effect of adalimumab in Korean...
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Correction to: A Novel Method to Differentiate Tonsil-Derived Mesenchymal Stem Cells In Vitro into Estrogen-Secreting Cells

Kim HY, Lee Y, Yoon HS, Kim YH, Cho KA, Woo SY, Kim HS, Park BY, Jung SC, Jo I, Park WJ, Park JW, Ryu KH

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A Novel Method to Differentiate Tonsil-Derived Mesenchymal Stem Cells In Vitro into Estrogen-Secreting Cells

Kim HY, Lee Y, Yoon HS, Kim YH, Cho KA, Woo SY, Kim HS, Park BY, Jung SC, Jo I, Park WJ, Park JW, Ryu KH

BACKGROUND: The advantages of tonsil-derived mesenchymal stem cells (TMSCs) over other mesenchymal stem cells (MSCs) include higher proliferation rates, various differentiation potentials, efficient immune-modulating capacity, and ease of obtainment. Specifically,...
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Real-world management of chronic myeloid leukemia in South Korea: the TARGET survey

Uhm J, Kim KH, Lee H, Kim H, Cassandra S, Joo I, Jung CW

Background: The global TARGET survey examined real-world management of chronic myeloid leukemia (CML) compared with international guideline recommendations. This report focused on the responses of physicians from South Korea compared...
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Implementation of Venoarterial Extracorporeal Membrane Oxygenation in Nonintubated Patients

Kim HA, Kim YS, Cho YH, Kim WS, Sung K, Jeong DS

Background: Although extracorporeal membrane oxygenation (ECMO) is generally performed percutaneously, the technology is deployed under sedation and necessitates endotracheal intubation. However, in some patients, the use of venoarterial (VA) ECMO...
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Basiliximab Induction with Delayed Calcineurin Inhibitors for High-Risk Lung Transplant Candidates

Kim HE, Paik HC, Jeong SJ, Park MS, Kim SY, Lee JG

Purpose Calcineurin inhibitor (CNI) use has improved lung transplantation outcomes. However, significant perioperative complications in patients receiving CNI can deteriorate the early course of lung transplantation. To date, there is no...
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Susceptibility-Weighted Imaging as a Distinctive Imaging Technique for Providing Complementary Information for Precise Diagnosis of Neurologic Disorder

Jeon BU, Yu IK, Kim TK, Kim HY, Hwang S

Various sequences have been developed for MRI to aid in the radiologic diagnosis. Among the various MR sequences, susceptibility-weighted imaging (SWI) is a high-spatial-resolution, threedimensional gradient-echo MR sequence, which is...
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Association of body composition with disease activity and disability in rheumatoid arthritis

Son KM, Kang SH, Seo YI, Kim HA

Background/Aims: To explore the associations between body composition and pain, disease activity, and disability in rheumatoid arthritis (RA). Methods: The study enrolled 335 patients with RA and underwent body composition measurement...
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Klebsiella pneumoniae infection secondary to bovine viral diarrhea in two prematurely born calves

Lee K, Kim HY, Choi EJ, Lee KK, So B, Jung JY

Abstract: This paper describes the development of neurological signs of two prematurely born calves four days after birth. The pathological examination results indicated fibrinopurulent polyserositis, including meningoencephalitis with suppurative bronchopneumonia....
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