J Korean Diabetes.  2012 Mar;13(1):15-17. 10.4093/jkd.2012.13.1.15.

Pathophysiology of Postprandial Hyperglycemia

• Lee JM

• KMID: 1436181
• DOI: http://doi.org/10.4093/jkd.2012.13.1.15

Abstract

The high incidence of atherosclerosis and cardiovascular disease is the leading cause of morbidity and mortality among diabetic patients. It is well known that postprandial hyperglycemia is an independent risk factor for diabetic complications and mortality. For better management of diabetic patients, effort must be put forth to not only achieve the HbA1c target, but also to control postprandial hyperglycemia. This article reviews the pathophysiology and clinical aspects of postprandial hyperglycemia to appropriately control blood glucose level.

Keyword

Hyperglycemia; Glycosylated hemoglobin A

MeSH Terms

Atherosclerosis
Blood Glucose
Cardiovascular Diseases
Diabetes Complications
Hemoglobin A, Glycosylated
Humans
Hyperglycemia
Incidence
Risk Factors
Blood Glucose
Hemoglobin A, Glycosylated

Figure

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  Fig. 1 Relationship between increase in HbA1c level and increase in fasting and postprandial glucose levels in 175 volunteers with normal glucose tolerance, impaired glucose tolerance, or type 2 diabetes mellitus. Adapted from Gerich. Arch Intern Med 2003;163.1306-16 [2].

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