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Efficacy and Safety of Pioglitazone versus Glimepiride after Metformin and Alogliptin Combination Therapy: A Randomized, Open-Label, Multicenter, Parallel-Controlled Study

Kim JM, Kim SS, Kim JH, Kim MK, Kim TN, Lee SH, Lee CW, Park JY, Kim ES, Lee KJ, Choi YS, Kim DK, Kim IJ

BACKGROUND: There is limited information regarding the optimal third-line therapy for managing type 2 diabetes mellitus (T2DM) that is inadequately controlled using dual combination therapy. This study assessed the efficacy...
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Evaluation of Analytical Performance of an Automated Glycated Hemoglobin Analyzer, HLC-723 G11

Chung YN, Yun SG, Cho Y

BACKGROUND: Glycated hemoglobin (HbA(1c)) is a key biomarker for the monitoring of glycemic balance in patients with diabetes. The aim of this study was to evaluate the performance of a...
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A Lower Baseline Urinary Glucose Excretion Predicts a Better Response to the Sodium Glucose Cotransporter 2 Inhibitor

Hwang YC, Kim JH, Lee BW, Lee WJ

We aimed to identify the clinical variables associated with a better glucose-lowering response to the sodium glucose cotransporter 2 inhibitor ipragliflozin in people with type 2 diabetes mellitus (T2DM). We...
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Three Months Monitored Metabolic Fitness Modulates Cardiovascular Risk Factors in Diabetic Patients

Cirilli I, Silvestri , Marcheggiani F, Olivieri F, Galeazzi R, Antonicelli R, Recchioni , Marcheselli F, Bacchetti , Tiano L, Orlando P

Cardiovascular diseases represent the leading cause of death and moderate physical exercise is associated with a reduction in cardiovascular risk. The aim of the study was to evaluate the correlation...
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Early Assessment of the Risk for Gestational Diabetes Mellitus: Can Fasting Parameters of Glucose Metabolism Contribute to Risk Prediction?

Falcone V, Kotzaeridi G, Breil MH, Rosicky I, Stopp T, Yerlikaya-Schatten G, Feichtinger M, Eppel W, Husslein P, Tura A, Göbl CS

BACKGROUND: An early identification of the risk groups might be beneficial in reducing morbidities in patients with gestational diabetes mellitus (GDM). Therefore, this study aimed to assess the biochemical predictors...
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Frey's procedure for chronic pancreatitis: a 10-year single-center experience in Korea

Kim HS, Lee JH, Park JS, Yoon DS

PURPOSE: Chronic pancreatitis (CP) is progressive inflammatory disease that leads to irreversible destruction of the pancreatic parenchyma. The main indications for surgical intervention in cases involving CP are intractable pain,...
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Dry Eye Syndrome and Morphological Changes of Meibomian Glands in Type 2 Diabetic Patients

Kwak JY, Choi KR, Han KE, Jun RM

PURPOSE: To evaluate the morphological changes of meibomian glands and dry eye syndrome in patients with type II diabetes. METHODS: The medical records of 72 diabetic patients referred to the ophthalmology...
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Screening for Gestational Diabetes Mellitus by Measuring Glycated Hemoglobin Can Reduce the Use of the Glucose Challenge Test

Maesa JM, Fernandez-Riejos P, Gonzalez-Rodriguez C, Sanchez-Margalet V

BACKGROUND: Physiological changes during pregnancy, such as dilutional anemia and a reduced half-life of red blood cells, have prevented the use of glycated Hb (HbA1c) as a biomarker for gestational...
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Predictors of Eating Disorders in Adolescents with Type 1 Diabetes

Park HR, Ju HO, Yoo JH

PURPOSE: The purpose of this study was to identify predictors of eating disorders in adolescents with type 1 diabetes, with the goal of providing data in support of nursing interventions...
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Anti-diabetic effects of blue honeyberry on high-fed-diet-induced type II diabetic mouse

Sharma A, Kim JW, Ku SK, Choi JS, Lee HJ

BACKGROUND/OBJECTIVE: The blue honeysuckle berry (Lonicera caerulea var. edulis L.) is a small deciduous shrub belonging to the Caprifoliaceae family that is native to Russia, China, Japan, and Korea. The...
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The effect of periodontal and prosthodontic therapy on glycemic control in patients with diabetes

Kim HK, Kim YG, Cho JH, Lee SK, Lee JM

PURPOSE: To evaluate the effect of periodontal and prosthodontic therapy on glycated hemoglobin A(HbA1c) level in patients with diabetes. MATERIALS AND METHODS: This is a retrospective study of 70 patients suffering...
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Importance of Hemoglobin A1c Levels for the Detection of Post-Surgical Infection Following Single-Level Lumbar Posterior Fusion in Patients with Diabetes

Hwang JU, Son DW, Kang KT, Lee SH, Lee JS, Song GS, Lee SW, Sung SK

OBJECTIVE: Several studies have reported that patients with diabetes mellitus (DM) are vulnerable to infection. However, the mechanism underlying this remains unclear. We hypothesized that preoperative blood glucose levels in...
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Low-Normal Free Thyroxine Levels in Euthyroid Male Are Associated with Prediabetes

Kim SW, Jeon JH, Moon JS, Jeon EJ, Kim MK, Lee IK, Seo JB, Park KG

Abnormal thyroid function is associated with impaired glucose homeostasis. This study aimed to determine whether free thyroxine (FT4) influences the prevalence of prediabetes in euthyroid subjects using a cross-sectional survey...
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Severity of Nonalcoholic Fatty Liver Disease in Type 2 Diabetes Mellitus: Relationship between Nongenetic Factors and PNPLA3/HSD17B13 Polymorphisms

Bellan M, Colletta C, Barbaglia , Salmi L, Clerici R, Mallela VR, Castello L, Saglietti , Carnevale Schianca GP, Minisini R, Pirisi M

BACKGROUND: The prevalence of nonalcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes mellitus (T2DM) is high, though its severity is often underestimated. Our aim is to provide...
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Longitudinal Changes of Body Composition Phenotypes and Their Association with Incident Type 2 Diabetes Mellitus during a 5-Year Follow-up in Koreans

Kim HK, Lee MJ, Kim EH, Bae SJ, Choe J, Kim CH, Park JY

BACKGROUND: To elucidate longitudinal changes of complex body composition phenotypes and their association with incident type 2 diabetes mellitus. METHODS: A total of 17,280 (mean age, 48.1±8.2 years) Korean adults who...
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Efficacy and Safety of Sodium-Glucose Cotransporter-2 Inhibitors in Korean Patients with Type 2 Diabetes Mellitus in Real-World Clinical Practice

Hong AR, Koo BK, Kim SW, Yi KH, Moon MK

BACKGROUND: This study aimed to evaluate the efficacy and safety of sodium-glucose cotransporter-2 (SGLT2) inhibitors in Korean patients who had inadequately controlled type 2 diabetes mellitus (T2DM) in real-world clinical...
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Factors Affecting Vascular Clogging, Wound Status and Bacterial Culture in Diabetic Foot Ulcers

Kim JL, Shin JY, Roh SG, Chang SC, Lee NH

BACKGROUND: We assumed that vascular clogging, wound status, and bacterial culture tests are significant characteristics in developing a treatment plan for diabetic patients with foot ulcers. The goal of our...
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The Association between Resting Heart Rate and Arterial Stiffness in Men

Doo SH, Choi HJ, Park SB, Jung D, Shim YN, Oh HJ

BACKGROUND: Early detection of vascular change may improve prediction of subclinical stage of cardiovascular disease, allowing intervention to prevent overt vascular damage. High heart rate is known to increase cardiovascular...
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Long-limb Roux-en-Y Reconstruction after Subtotal Gastrectomy to Treat Severe Diabetic Gastroparesis

Park JM, Kim JW, Chi KC

The role of surgical intervention in patients with diabetic gastroparesis is unclear. We report a case of a 37-year-old man with a history of recurrent episodes of vomiting and long-standing...
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Differing Associations between Fatty Liver and Dyslipidemia According to the Degree of Hepatic Steatosis in Korea

Han JM, Kim HI, Lee YJ, Lee JW, Kim KM, Bae JC

OBJECTIVE: Fatty liver is associated with insulin resistance-related diseases, such as dyslipidemia, obesity, and type 2 diabetes. The aim of this study was to evaluate the association of dyslipidemia with...
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