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Differences in omega-5-gliadin allergy: East versus West

Li PH, Thomas I, Wong JC, Rutkowski , Lau CS

BACKGROUND: Omega-5-gliadin (O5G) allergy, also known as wheat-dependent exercise-induced anaphylaxis, is commonly reported in the Western, but not Asian, populations. Although significant differences in O5G allergy presentation across different populations...
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Clinical and Laboratory Findings of Barley Allergy in Korean Children: a Single Hospital Based Retrospective Study

Lee E, Jeong K, Lee J, Jeon SA, Park B, Lee H, Lee S

BACKGROUND: Barley is a grain that is consumed in various forms in Asia. Studies on barley allergy are limited to a few case reports about hypersensitivity reactions to beer, but...
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Clinical Features and Culprit Food Allergens of Korean Adult Food Allergy Patients: A Cross-Sectional Single-Institute Study

Lee SC, Kim SR, Park KH, Lee JH, Park JW

PURPOSE: To investigate the causative allergens and clinical characteristics of Korean adult patients with food allergy (FA). METHODS: This retrospective, cross-sectional single-institutional study enrolled Korean adult patients (n = 812) suspected...
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Reduction Rate of Specific IgE Level as a Predictor of Persistent Egg Allergy in Children

Kim JD, Kim SY, Kwak EJ, Sol IS, Kim MJ, Kim YH, Kim KW, Sohn MH

PURPOSE: Egg is the most common food allergen in infants. However, the natural course of egg allergy has not been fully elucidated. This study aimed to describe clinical characteristics and...
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The current status and issue of food allergen labeling in Korea

Jeon YH, Kim HH, Park YM, Jang GC, Kim HY, Yum HY, Kim J, Ahn K, Min TK, Pyun BY, Lee S, Kim KW, Kim YH, Lee J, Lee SY, Kim WK, Song TW, Kim JH, Lee YJ, The Korean Academy of Pediatric Allergy and Respiratory Diseases, Food Allergy and Atopic Dermatitis Study Group

With increasing need to prevent serious food allergy reactions, Korean food allergen labeling regulation has been revised repeatedly. This paper aims to summarize current statuses of food allergen labeling in...
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Infantile Anaphylaxis in Korea: a Multicenter Retrospective Case Study

Jeon YH, Lee S, Ahn K, Lee SY, Kim KW, Kim HH, Kim JH, Yum HY, Kim WK, Park YM, Song TW, Kim J, Lee YJ, Jang GC, Jeong K, Kim YH, Min TK, Pyun BY, on behalf of the Food Allergy and Atopic Dermatitis (FAAD) Study Group in the Korean Academy of Pediatric Allergy and Respiratory Disease

BACKGROUND: Anaphylaxis is increasing in young children. The aim of the present study was to analyze the clinical characteristics of anaphylaxis in Korean infants, with a focus on food triggers. METHODS:...
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Role of the Duodenum in the Pathogenesis of Functional Dyspepsia: A Paradigm Shift

Jung HK, Talley NJ

  • KMID: 2417379
  • J Neurogastroenterol Motil.
  • 2018 Jul;24(3):345-354.
  • doi: 10.5056/jnm18060
Functional dyspepsia (FD) is a common disorder characterized by chronic epigastric pain or burning, or bothersome postprandial fullness or early satiation, without a definitive organic cause. The pathogenesis of FD...
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Oral food challenges: result of a 16-year experience at a major teaching hospital in Thailand

Srisuwatchari W, Vichyanond P

BACKGROUND: Prevalence of food allergy is increasing all over the world including in Asia. Diagnosis of food allergy in Asia is usually made after family complaints or by elimination and/or...
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An unusual case of infant seizures with anaphylaxis to wheat

Chong KW, Ling S, Loh W

Wheat allergy is one of the commonest food allergies in childhood and it typically presents with IgE mediated reactions, including anaphylaxis. Seizures are not typically reported to be a direct...
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Quality characteristics of improvement pellet nuruk inoculated from Aspergillus luchuensis 34-1

Jung EH, Mun JY, Kim SY, Yeo SH

Aspergillus luchuensis 34-1 was inoculated into wheat pellets with different conditions of raw materials to produce nuruk. The degree of substrate reactivity improvement of steam treated raw materials compared with...
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Quercetin induces cell death in cervical cancer by reducing O-GlcNAcylation of adenosine monophosphate-activated protein kinase

Ali A, Kim MJ, Kim MY, Lee HJ, Roh GS, Kim HJ, Cho GJ, Choi WS

Hyper-O-GlcNAcylation is a general feature of cancer which contributes to various cancer phenotypes, including cell proliferation and cell growth. Quercetin, a naturally occurring dietary flavonoid, has been reported to reduce...
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Comparison of Singleplex Specific IgE Detection Immunoassays: ImmunoCAP Phadia 250 and Immulite 2000 3gAllergy

Park KH, Lee J, Sim DW, Lee SC

BACKGROUND: The identification of clinically meaningful specific immunoglobulin E (sIgE) is important for the diagnosis and management of allergic diseases. Various in vitro sIgE detection methods are available worldwide. Depending...
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Age-Based Causes and Clinical Characteristics of Immediate-Type Food Allergy in Korean Children

Jeong K, Kim J, Ahn K, Lee SY, Min TK, Pyun BY, Kim YH, Kim KW, Sohn MH, Kim KE, Jang GC, Song TW, Kim JH, Jeon YH, Lee YJ, Park YM, Yum HY, Kim HH, Kim WK, Lee S

PURPOSE: Age-based causes and clinical characteristics of immediate-type food allergy (FA) have not been sufficiently studied. Therefore, we investigated age-dependent clinical profiles of FA in Korean children through an extensive...
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Pros and Cons While Looking Through an Asian Window on the Rome IV Criteria for Irritable Bowel Syndrome: Pros

Ghoshal UC

  • KMID: 2387823
  • J Neurogastroenterol Motil.
  • 2017 Jul;23(3):334-340.
  • doi: 10.5056/jnm17020
A decade after Rome III, in 2016, Rome IV criteria were published. There are major differences between Rome IV and the earlier iteration, some of which are in line with...
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The association between Staphylococcus aureus colonization and food sensitization in children with atopic dermatitis

Hwang YH, Lee SH, Kim BK, Kim SW

PURPOSE: Atopic dermatitis is often accompanied by food allergies which occur through skin barrier defects. Especially Staphylococcus aureus colonization can exacerbate skin barrier defects that cause sensitization and increase specific...
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Wheatgrass extract inhibits hypoxia-inducible factor-1-mediated epithelial-mesenchymal transition in A549 cells

Do NY, Shin HJ, Lee JE

BACKGROUND/OBJECTIVES: Epithelial-mesenchymal transition (EMT) is involved in not only cancer development and metastasis but also non-cancerous conditions. Hypoxia is one of the proposed critical factors contributing to formation of chronic...
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IgE-mediated food allergies in children: prevalence, triggers, and management

Lee S

Food allergy (FA) is a serious health problem, and severe FA such as food-induced anaphylaxis can often be life threatening. The incidence of FA has been increasing especially in children....
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Evaluation of the results of oral food challenges conducted in specialized and general hospitals

Sakai K, Sasaki K, Furuta T, Sugiura S, Watanabe Y, Kobayashi , Kawabe T, Morishita , Nakanishi , Ito K

BACKGROUND: Oral food challenge (OFC) tests are conducted in both specialized institutions and general hospitals. We aimed to compare the severity of the conditions of the patients between these 2...
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A case of celiac disease with neurologic manifestations misdiagnosed as amyotrophic lateral sclerosis

Ham H, Lee BI, Oh HJ, Park SH, Kim JS, Park JM, Cho YS, Choi MG

Celiac disease (CD) is an immune-mediated enteropathy and is a rare disease in Asia, including in Korea. However, the ingestion of wheat products, which can act as a precipitating factor...
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Alterations of Food-specific Serum IgG4 Titers to Common Food Antigens in Patients With Irritable Bowel Syndrome

Lee HS, Lee KJ

  • KMID: 2395427
  • J Neurogastroenterol Motil.
  • 2017 Oct;23(4):578-584.
  • doi: 10.5056/jnm17054
BACKGROUND/AIMS: The role of dietary factors in the pathogenesis of irritable bowel syndrome (IBS) is still unclear. The aim of this study was to compare IgG4 levels to common food...
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