Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

more+
SELECT FILTER
 
Close

PUBLICATION DATE

768 results
Display

Evogliptin, a Dipeptidyl Peptidase-4 Inhibitor, Attenuates Renal Fibrosis Caused by Unilateral Ureteral Obstruction in Mice

Kim MJ, Kim NY, Jung YA, Lee S, Jung GS, Kim JG, Lee IK, Lee S, Choi YK, Park KG

Renal fibrosis is considered to be the final common outcome of chronic kidney disease. Dipeptidyl peptidase-4 (DPP-4) inhibitors have demonstrated protective effects against diabetic kidney disease. However, the anti-fibrotic effect...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Fibroblast Growth Factor 21 Attenuates Diabetes-Induced Renal Fibrosis by Negatively Regulating TGF-β-p53-Smad2/3-Mediated Epithelial-to-Mesenchymal Transition via Activation of AKT

Lin S, Yu L, Ni Y, He L, Weng X, Lu X, Zhang C

BACKGROUND: Epithelial-to-mesenchymal transition (EMT) is required for renal fibrosis, which is a characteristic of diabetic nephropathy (DN). Our previous study demonstrated that fibroblast growth factor 21 (FGF21) prevented DN associated...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Clinicopathological Significance of SMAD4 Expression in Breast Cancer

Woo JS, Chung MS, Paik SS

PURPOSE: SMAD4 is a member of the SMAD family and acts as a central mediator of transforming growth factor beta signaling. Little is known about SMAD4 expression and its prognostic...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Shen-Kang protects against tacrolimus-induced renal injury

Zhang LY, Jin J, Luo K, Piao SG, Zheng HL, Jin JZ, Lim SW, Choi BS, Yang CW, Li C

BACKGROUND/AIMS: Evidence suggests that Shen-Kang (SK), a traditional Chinese herbal medicine, protects against various types of renal injury. In this study, we evaluated whether SK treatment confers renoprotection in a...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Increased CD68/TGFβ Co-expressing Microglia/Macrophages after Transient Middle Cerebral Artery Occlusion in Rhesus Monkeys

Yeo HG, Hong JJ, Lee Y, Yi KS, Jeon CY, Park J, Won J, Seo J, Ahn YJ, Kim K, Baek SH, Hwang EH, Kim G, Jin YB, Jeong KJ, Koo BS, Kang P, Lim KS, Kim SU, Huh JW, Kim YH, Son Y, Kim JS, Choi CH, Cha SH, Lee SR

The function of microglia/macrophages after ischemic stroke is poorly understood. This study examines the role of microglia/macrophages in the focal infarct area after transient middle cerebral artery occlusion (MCAO) in...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Preparation and Characterization of Human Adipose Tissue-Derived Extracellular Matrix, Growth Factors, and Stem Cells: A Concise Review

Chun SY, Lim JO, Lee EH, Han MH, Ha YS, Lee JN, Kim BS, Park MJ, Yeo M, Jung B, Kwon TG

BACKGROUND: Human adipose tissue is routinely discarded as medical waste. However, this tissue may have valuable clinical applications since methods have been devised to effectively isolate adipose-derived extracellular matrix (ECM),...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Significance of NOTCH Pathway in the Development of Fibrosis in Systemic Sclerosis

Zmorzyński S, Styk W, Filip AA, Krasowska

Systemic sclerosis (SSc) is an autoimmune disorder characterized by the fibrosis of skin, heart, lung, and kidney as well. Excessive activation of fibroblasts is associated with higher expression of Notch1...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effect of Manuka Honey on Transforming Growth Factor Beta-1-Induced Extracelluar Matrix Production in Nasal Polyp Derived Fibroblasts

Kil BK, Kim BM, Kang BJ, Ye MK, Shin SH

BACKGROUND AND OBJECTIVES: Manuka honey has anti-microbial, anti-inflammatory, and anti-proliferative action with a high concentration of methylglyoxal compound. It is also effective in killing Staphylococcus aureus biofilm and effective for...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Conditioned Medium from Tonsil-Derived Mesenchymal Stem Cells Relieves CClâ‚„-Induced Liver Fibrosis in Mice

Kim YH, Cho KA, Park M, Kim HS, Park JW, Woo SY, Ryu KH

BACKGROUND: The liver is an organ with remarkable regenerative capacity; however, once chronic fibrosis occurs, liver failure follows, with high mortality and morbidity rates. Continuous exposure to proinflammatory stimuli exaggerates...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Effects of Retinoic Acid and MAPK Inhibitors on Phosphorylation of Smad2/3 Induced by Transforming Growth Factor β1

Lee SH, Shin JH, Shin MH, Kim YS, Chung KS, Song JH, Kim SY, Kim EY, Jung JY, Kang YA, Chang J, Park MS

BACKGROUND: Transforming growth factor β (TGF-β), retinoic acid (RA), p38 mitogen-activated protein kinase (MAPK), and MEK signaling play critical roles in cell differentiation, proliferation, and apoptosis. We investigated the effect...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Association Between Epithelial Cytokines and Clinical Phenotypes of Elderly Asthma

Ulambayar , Lee SH, Yang EM, Ye YM, Park HS

PURPOSE: Asthma in the elderly has different clinical features including more severe phenotypes with higher comorbidities. Epithelial cells are known to initiate innate/adaptive immune responses in asthmatic airways. We investigated...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Role of Tripartite Motif Family Proteins in TGF-β Signaling Pathway and Cancer

Lee HJ

TGF-β signaling plays a tumor suppressive role in normal and premalignant cells but promotes tumor progression during the late stages of tumor development. The TGF-β signaling pathway is tightly regulated...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
TGF-β1 upregulates the expression of hyaluronan synthase 2 and hyaluronan synthesis in culture models of equine articular chondrocytes

Ongchai S, Somnoo O, Kongdang P, Peansukmanee S, Tangyuenyong S

We investigated the effect of transforming growth factor beta 1 (TGF-β1) on equine hyaluronan synthase 2 (HAS2) gene expression and hyaluronan (HA) synthesis in culture models of articular chondrocytes. Equine...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Recent Topics in Fibrodysplasia Ossificans Progressiva

Katagiri T, Tsukamoto , Nakachi Y, Kuratani M

Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease that is characterized by the formation of heterotopic bone tissues in soft tissues, such as skeletal muscle, ligament, and tendon. It...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Development of an easy-to-handle murine model for the characterization of radiation-induced gross and molecular changes in skin

Chang HP, Cho JH, Lee WJ, Roh H, Lee DW

BACKGROUND: Radiation-induced skin injury is a dose-limiting complication of radiotherapy. To investigate this problem and to develop a framework for making decisions on treatment and dose prescription, a murine model...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Hypoxia-Inducible Factor 1α Regulates the Transforming Growth Factor β1/SMAD Family Member 3 Pathway to Promote Breast Cancer Progression

Peng J, Wang X, Ran L, Song J, Luo R, Wang Y

PURPOSE: The transforming growth factor β1 (TGF-β1)/SMAD family member 3 (SMAD3) pathway, and hypoxia-inducible factor 1α (HIF-1α) are two key players in various types of malignancies including breast cancer. The...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Detection of progressive and regressive phase and LINE-1 retrotransposon in transfected dogs with transmissible venereal tumor during chemotherapy

Atalay Vural S, Haziroglu , Vural MR, Polat IM, Tunc AS

Canine transmissible venereal tumor (CTVT) is a tumor that commonly occurs in genital and extragenital sites of both genders. Long interspersed nuclear elements (LINE-1) retrotransposon has a pivotal role in...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
TGF-β induces Smad2 Phosphorylation, ARE Induction, and Trophoblast Differentiation

Albers RE, Selesniemi K, Natale DR, Brown TL

BACKGROUND: Transforming growth factor beta (TGF-β) signaling has been shown to control a large number of critical cellular actions such as cell death, differentiation, and development and has been implicated...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Differential Role of Transforming Growth Factor-beta in an Osteoarthritic or a Healthy Joint

van der Kraan PM

Transforming growth factor-β (TGF-β) is a cytokine that plays an important role in both normal joints and joints affected by osteoarthritis (OA), the most common joint disease. However, the role...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The long non-coding RNA uc.4 influences cell differentiation through the TGF-beta signaling pathway

Cheng Z, Zhang Q, Yin A, Feng M, Li H, Liu H, Li Y, Qian L

In a previous study, we screened thousands of long non-coding RNAs (lncRNAs) to assess their potential relationship with congenital heart disease (CHD). In this study, uc.4 attracted our attention because...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2023 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr