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Changes in the Ganglion Cell-inner Plexiform Layer after Consecutive Intravitreal Injections of Anti-vascular Endothelial Growth Factor in Age-related Macular Degeneration Patients

Kim SY, Yoon MH, Chin HS

PURPOSE: To investigate the effect of intravitreal anti-vascular endothelial growth factor (VEGF) injections on ganglion cell-inner plexiform layer (GCIPL) thickness in patients with age-related macular degeneration (AMD). METHODS: This retrospective study...
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Status of Usage of Anti-vascular Endothelial Growth Factor in Age-related Macular Degeneration

Cho S, Shin SJ, Suh JK, Tchoe H, Kang MJ, Yang J, Jee D

PURPOSE: To evaluate the current use of intravitreal injections of anti-vascular endothelial growth factor (anti-VEGF) in patients with age-related macular degeneration (AMD). METHODS: We analyzed the number and medical costs of...
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Intravitreal Injection of Anti-vascular Endothelial Growth Factor in Age-related Macular Degeneration: a Systematic Review

Kang MJ, Shin SJ, Suh JK, Cho S, Tchoe H, Yang J, Jee D

PURPOSE: To compare the efficacy and safety of intravitreal injections of bevacizumab, ranibizumab, and aflibercept for the treatment of new patients with age-related macular degeneration (AMD). METHODS: We conducted an update...
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Budget Impact Analysis of Anti-vascular Endothelial Growth Factor in Patients with Diabetic Macular Edema

Yang J, Shin SJ, Suh JK, Tchoe H, Cho S, Kang MJ, Jee D

PURPOSE: This study investigated the optimal strategy to minimize budgetary constraints on National Health Insurance (NHI) services, while maximizing the number of diabetic macular edema (DME) patients who receive anti-vascular...
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Use of Anti-vascular Endothelial Growth Factors for Diabetic Retnopathy: National Health Insurance Claims Data

Cho S, Shin SJ, Suh JK, Tchoe H, Yang J, Kang MJ, Jee D

PURPOSE: To evaluate the current use of intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) in patients with diabetic retinopathy. METHODS: We determined the current number of diabetic retinopathy patients and...
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Analysis of Intraocular Pressure Elevation after Intravitreal Injection of Ranibizumab and Aflibercept

Moon TK, Ha JY, Sung MS, Park SW

PURPOSE: To evaluate long-term intraocular pressure (IOP) and risk of IOP elevation after intravitreal injection of ranibizumab or aflibercept in patients with age-related macular degeneration (AMD). METHODS: From January 2013 to...
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Short-term Efficacy and Safety of Ranibizumab for Neovascular Age-related Macular Degeneration in the Real World: A Post-marketing Surveillance Study

Woo SJ, Cho GE, Cho JH

PURPOSE: To investigate the short-term efficacy and safety of ranibizumab in the routine clinical setting in patients with neovascular age-related macular degeneration and to analyze the associated factors for visual...
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Prevalence of Exudative Age-related Macular Degeneration and Projections of the Cost of Ranibizumab in Korea

Ryu S, Kim DW, Rim TH, Chung EJ, Kim J

PURPOSE: To analyze the incidence and prevalence of exudative age-related macular degeneration (AMD) and to predict the future AMD populations and health expenditures of intravitreal ranibizumab injection. METHODS: From 2010 to...
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Meta-analysis of Intravitreal Injection of Anti-vascular Endothelial Growth Factors for Diabetic Macular Edema

Tchoe H, Shin SJ, Suh JK, Cho S, Yang J, Kang MJ, Jee D

PURPOSE: Intravitreal aflibercept, ranibizumab, bevacizumab, and dexamethasone are the most widely used drugs in the treatment of diabetic macular edema (DME). The aim of this study was to compare the...
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Influence of Axial Length on Recurrence of Wet Age-related Macular Degeneration after Initial Treatment

Cho SY, Lee YG, Han SY, Tae KS, Kim JW, Kim CG, Lee DW, Kim JH

PURPOSE: To evaluate the influence of axial length on the recurrence of wet age-related macular degeneration (AMD) after anti-vascular endothelial growth factor therapy. METHODS: A retrospective review of the medical records...
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Clinical Changes after Switching from Ranibizumab/Aflibercept to Bevacizumab in Exudative Age-related Macular Degeneration

Lee IH, Lee JJ, Kwon HJ, Park SW, Lee JE

PURPOSE: This study was performed to investigate the changes in clinical findings after switching from ranibizumab or aflibercept to bevacizumab due to the limited number of insured injections in patients...
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Effects of Ranibizumab, Bevacizumab, and Aflibercept on Senescent Retinal Pigment Epithelial Cells

Chae JB, Rho CR, Shin JA, Lyu J, Kang S

PURPOSE: Anti-vascular endothelial growth factor (VEGF) agents have been used for the last 10 years, but their safety profile, including cytotoxicity against various ocular cells such as retinal pigment epithelial...
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Effectiveness of Intravitreal Ranibizumab for Diabetic Macular Edema with Serous Retinal Detachment

Kaya M, Karahan E, Ozturk T, Kocak N, Kaynak S

PURPOSE: To evaluate the effectiveness of intravitreal injection of ranibizumab (IVR) in treating diabetic macular edema (DME) with serous retinal detachment (SRD) based on spectral domain optical coherence tomography (SD-OCT)...
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Intravitreal Anti-vascular Endothelial Growth Factor Injections to Treat Neovascular Age-related Macular Degeneration: Long-term Treatment Outcomes

Park YJ, Son GS, Kim YJ, Kim JG, Yoon YH, Lee JY

PURPOSE: We assessed the visual and anatomical outcomes, and the safety profile of long-term intravitreal anti-vascular endothelial growth factor (VEGF) injections (aflibercept, ranibizumab, and bevacizumab) given to treat neovascular age-related...
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Anti-vascular Endothelial Growth Factor Treatment of Retinopathy of Prematurity: Efficacy, Safety, and Anatomical Outcomes

Kang HG, Choi EY, Byeon SH, Kim SS, Koh HJ, Lee SC, Kim M

PURPOSE: To investigate the efficacy, safety, and anatomical outcomes associated with intravitreal anti-vascular endothelial growth factor (VEGF) treatment of retinopathy of prematurity (ROP). METHODS: We performed a retrospective review of intravitreal...
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Final Impact of Anti-Vascular Endothelial Growth Factor Treatment in Age-related Macular Degeneration

Yang J, Shin SJ, Suh JK, Cho S, Tchoe H, Kang MJ, Jee D

PURPOSE: To evaluate the effects of anti-vascular endothelial growth factor (VEGF) treatment on the healthcare-related finances of patients with age-related macular degeneration. METHODS: Changes in health care financing due to newly...
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Efficacy of Primary Intravitreal Ranibizumab Injection for Treatment of Type 1 Retinopathy of Prematurity

Chung GC, Moon SH

PURPOSE: To evaluate the effectiveness and safety of primary intravitreal ranibizumab injection as a treatment for retinopathy of prematurity. METHODS: Retrospective analysis of the medical records of patients diagnosed with retinopathy...
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Fourteen Anti-vascular Endothelial Growth Factor Injections for Age-related Macular Degeneration: Ending Period and Clinical Outcome

Han JW, Kim JW, Kim CG, Lee DW, Han JI, Lew YJ, Kim JH

PURPOSE: To evaluate the clinical course of patients who had completed 14 ranibizumab or aflibercept monocular treatments. METHODS: Retrospective medical record analysis was performed to 24 patients who were diagnosed with...
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Full-thickness Macular Hole after Intravitreal Aflibercept Injection in a Patient with Wet Age-related Macular Degeneration

Lee G, Lee S

PURPOSE: To report a case of full-thickness macular hole following intravitreal aflibercept injection in a patient with wet age-related macular degeneration (AMD). CASE SUMMARY: A 70-year-old man presented to our department...
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Intravitreal Ranibizumab Injection in Adult-onset Coats' Disease: A Case Report

Kim HU, Shin SH, Park SP

PURPOSE: To report a case of adult-onset Coats' disease which showed decreased retinal edema and improved visual acuity following intravitreal ranibizumab injection. CASE SUMMARY: A 21-year-old woman visited our hospital for...
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