- What Is the Significance of Long Non-coding RNA HOX Transcript Antisense Intergenic RNA in Gastric Cancer?
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Lee SK
- KMID: 1730923
- Korean J Gastroenterol.
- 2014 Feb;63(2):137-139.
- doi: 10.4166/kjg.2014.63.2.137
No abstract available. -
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- Potential Implications of Long Noncoding RNAs in Autoimmune Diseases
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Hur K, Kim SH, Kim JM
- KMID: 2438912
- Immune Netw.
- 2019 Feb;19(1):e4.
- doi: 10.4110/in.2019.19.e4
Long noncoding RNAs (lncRNAs) are non-protein coding RNAs of more than 200 nucleotides in length. Despite the term “noncodingâ€, lncRNAs have been reported to be involved in gene expression. Accumulating... -
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- Application of Long Non-coding RNAs in Gastric Cancer
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Lee SK
- KMID: 2439827
- Korean J Helicobacter Up Gastrointest Res.
- 2018 Sep;18(3):174-179.
- doi: 10.7704/kjhugr.2018.18.3.174
Gastric cancer remains a big problem in terms of incidence or mortality; various mechanisms to explain its development and progression have been studied. Recently, long non-coding RNAs (lncRNAs) have been... -
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- Regulation Mechanism of Long Noncoding RNAs in Colon Cancer Development and Progression
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Tang X, Qiao X, Chen C, Liu Y, Zhu J, Liu J
- KMID: 2450186
- Yonsei Med J.
- 2019 Apr;60(4):319-325.
- doi: 10.3349/ymj.2019.60.4.319
Colorectal cancer (CRC) is the second most common cause of cancer-related death worldwide, and its high rates of relapse and metastasis are associated with a poor prognosis. Despite extensive research,... -
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- Select Macrophage Noncoding RNAs of Interest in Cardiovascular Disease
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Enchill Z, Lantz C, Thorp EB
- KMID: 2470807
- J Lipid Atheroscler.
- 2020 Jan;9(1):153-161.
- doi: 10.12997/jla.2020.9.1.153
Cardiovascular disease remains a leading cause of morbidity and mortality worldwide. Aspects of disease severity that are associated with heightened inflammation, such as during atherosclerosis or after myocardial infarction, are... -
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- Epigenetic Silencing of MORT Is an Early Event in Cancer and Is Associated with Luminal, Receptor Positive Breast Tumor Subtypes
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Vrba L, Futscher B
- KMID: 2389758
- J Breast Cancer.
- 2017 Jun;20(2):198-202.
- doi: 10.4048/jbc.2017.20.2.198
Immortality is an essential characteristic of cancer cells; a recent transcriptomic study of epithelial cell immortalization has linked epigenetic silencing of the long noncoding RNA Mortal Obligate RNA Transcript (MORT;... -
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- BRAF-Activated Long Noncoding RNA Modulates Papillary Thyroid Carcinoma Cell Proliferation through Regulating Thyroid Stimulating Hormone Receptor
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Zheng H, Wang M, Jiang L, Chu H, Hu J, Ning J, Li B, Wang D, Xu J
- KMID: 2454348
- Cancer Res Treat.
- 2016 Apr;48(2):698-707.
- doi: 10.4143/crt.2015.118
PURPOSE: The importance of long noncoding RNAs (lncRNAs) in tumorigenesis has recently been demonstrated. However, the role of lncRNAs in development of thyroid cancer remains largely unknown. MATERIALS AND METHODS: Using... -
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- Noncoding RNAs as therapeutic targets in early stage diabetic kidney disease
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Kato M
- KMID: 2447159
- Kidney Res Clin Pract.
- 2018 Sep;37(3):197-209.
- doi: 10.23876/j.krcp.2018.37.3.197
Diabetic kidney disease (DKD) is a major renal complication of diabetes that leads to renal dysfunction and end-stage renal disease (ESRD). Major features of DKD include accumulation of extracellular matrix... -
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- FoxD2-AS1 is a prognostic factor in glioma and promotes temozolomide resistance in a Oâ¶-methylguanine-DNA methyltransferase-dependent manner
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Shangguan , Lv X, Tian N
- KMID: 2461040
- Korean J Physiol Pharmacol.
- 2019 Nov;23(6):475-482.
- doi: 10.4196/kjpp.2019.23.6.475
Glioma is the most common brain tumor with a dismal prognosis. While temozolomide (TMZ) based chemotherapy significantly improves survival in glioma patients, resistance against this compound commonly leads to glioma... -
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- Role of Long Non-coding Ribonucleic Acid in Gastrointestinal Cancer
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Park CH, Lee SK
- KMID: 1711287
- Korean J Gastroenterol.
- 2013 Dec;62(6):317-326.
- doi: 10.4166/kjg.2013.62.6.317
With the improvement of high-throughput genomic technology such as microarray and next-generation sequencing over the last ten to twenty year, we have come to know that the portion of the... -
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- Long non-coding RNA linc00152 acting as a promising oncogene in cancer progression
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Seo D, Kim D, Kim W
- KMID: 2468862
- Genomics Inform.
- 2019 Dec;17(4):e36.
- doi: 10.5808/GI.2019.17.4.e36
The incidence and mortality rate of cancer continues to gradually increase, although considerable research effort has been directed at elucidating the molecular mechanisms underlying biomarkers responsible for tumorigenesis. Accumulated evidence... -
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- Long Noncoding RNA MHRT Protects Cardiomyocytes against H2O2-Induced Apoptosis
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Zhang J, Gao C, Meng M, Tang H
- KMID: 2170536
- Biomol Ther.
- 2016 Jan;24(1):19-24.
- doi: 10.4062/biomolther.2015.066
Acute myocardial infarction (AMI) remains a leading cause of morbidity and mortality worldwide. The exploration of new biomarkers with high sensitivity and specificity for early diagnosis of AMI therefore becomes... -
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- c-Myc-Induced Long Non-Coding RNA Small Nucleolar RNA Host Gene 7 Regulates Glycolysis in Breast Cancer
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Zhang L, Fu Y, Guo H
- KMID: 2470891
- J Breast Cancer.
- 2019 Dec;22(4):533-547.
- doi: 10.4048/jbc.2019.22.e54
PURPOSE: Recent studies have shown that long non-coding RNA (lncRNA) play an important role in cancer metabolism and development. The lncRNA small nucleolar RNA host gene 7 (SNHG7) was reported... -
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- Silencing of Long Non-Coding RNA MALAT1 Promotes Apoptosis of Glioma Cells
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Xiang J, Guo S, Jiang S, Xu Y, Li J, Li L, Xiang J
- KMID: 2373664
- J Korean Med Sci.
- 2016 May;31(5):688-694.
- doi: 10.3346/jkms.2016.31.5.688
The metastasis-associated lung adenocarcinoma transcription 1 (MALAT1) is a highly conserved long non-coding RNA (lncRNA) gene. However, little is known about the pathological role of lncRNA MALAT1 in glioma. In... -
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- Roles of Oncogenic Long Non-coding RNAs in Cancer Development
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Do H, Kim W
- KMID: 2439208
- Genomics Inform.
- 2018 Dec;16(4):e18.
- doi: 10.5808/GI.2018.16.4.e18
Long non-coding RNAs (lncRNAs) are classified as RNAs that are longer than 200 nucleotides and cannot be translated into protein. Several studies have demonstrated that lncRNAs are directly or indirectly... -
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- Roles of Long Non-Coding RNAs on Tumorigenesis and Glioma Development
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Park JY, Lee JE, Park JB, Yoo H, Lee SH, Kim JH
- KMID: 1734662
- Brain Tumor Res Treat.
- 2014 Apr;2(1):1-6.
- doi: 10.14791/btrt.2014.2.1.1
More than 98% of eukaryotic transcriptomes are composed of non-coding RNAs with no functional protein-coding capacity. Those transcripts also include tens of thousands of long non-coding RNAs (lncRNAs) which are... -
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- Upregulated Long Noncoding RNA LINC01234 Predicts Unfavorable Prognosis for Colorectal Cancer and Negatively Correlates With KLF6 Expression
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Jiang X, Zhu Q, Wu P, Zhou F, Chen J
- KMID: 2460913
- Ann Lab Med.
- 2020 Mar;40(2):155-163.
- doi: 10.3343/alm.2020.40.2.155
BACKGROUND: LINC01234, a long noncoding RNA (lncRNA), is overexpressed in several cancers, including colorectal cancer (CRC). We investigated the role of LINC01234 in CRC development and confirmed its correlation with... -
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- HOTAIR Long Non-coding RNA: Characterizing the Locus Features by the In Silico Approaches
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Hajjari M, Rahnama S
- KMID: 2404055
- Genomics Inform.
- 2017 Dec;15(4):170-177.
- doi: 10.5808/GI.2017.15.4.170
HOTAIR is an lncRNA that has been known to have an oncogenic role in different cancers. There is limited knowledge of genetic and epigenetic elements and their interactions for the... -
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- Circulating HOTAIR LncRNA Is Potentially Up-regulated in Coronary Artery Disease
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Avazpour N, Hajjari M, Yazdankhah S, Sahni A, Foroughmand AM
- KMID: 2439215
- Genomics Inform.
- 2018 Dec;16(4):e25.
- doi: 10.5808/GI.2018.16.4.e25
Coronary artery disease (CAD) is one of the leading causes of death and disability all around the world. Recent studies have revealed that aberrantly regulated long non-coding RNA (lncRNA) as... -
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- Long Non-Coding RNA LINC00525 Promotes the Stemness and Chemoresistance of Colorectal Cancer by Targeting miR-507/ELK3 Axis
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Wang S, Li J, Yang X
- KMID: 2465904
- Int J Stem Cells.
- 2019 Jul;12(2):347-359.
- doi: 10.15283/ijsc19041
BACKGROUND AND OBJECTIVES: This study aims to explore the effects of a long non-coding RNA, LINC00525, on colorectal cancer (CRC) and its underlying molecular mechanisms. METHODS: The qPCR, MTT, colony formation,... -
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