- Serum nitrotyrosine concentration in dogs with myxomatous mitral valve disease
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Kim JS, Park JS, Park HJ, Seo KW, Song KH
- KMID: 2376874
- Korean J Vet Res.
- 2017 Mar;57(1):17-21.
- doi: 10.14405/kjvr.2017.57.1.17
The aim of this study was to compare serum nitrotyrosine concentrations in healthy dogs with those in dogs with myxomatous mitral valve disease (MMVD). Fifty client-owned dogs were included in... -
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- Phytochemical Analysis of the Phenolic Fat-Suppressing Substances in the Leaves of Lactuca raddeana in 3T3-L1 Adipocytes
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Nugroho A, Choi JS, An HJ, Park HJ
- KMID: 2409598
- Nat Prod Sci.
- 2015 Mar;21(1):42-48.
- doi: 10.0000/nps.2015.21.1.42
Lactuca raddeana (Compositae) is used to treat obesity and complications due to diabetes. The five phenolic compounds including chlorogenic acid, chicoric acid, luteolin 7-O-glucoside, luteolin 7-O-glucuronide, luteolin were qualitatively identified... -
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- Analysis of Flavonoid Composition of Korean Herbs in the Family of Compositae and their Utilization for Health
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Nugroho A, Choi JS, Park HJ
- KMID: 2312914
- Nat Prod Sci.
- 2016 Mar;22(1):1-12.
- doi: 10.20307/nps.2016.22.1.1
Compositional differences in flavonoids are varied in the big family of Compositae. By summarizing our previous analytical studies and other scientific evidences, new strategy will be possible to further analyze... -
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- Mass Spectrometry Analysis for Nitration of Proteins
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Kim KP
- KMID: 2168241
- Hanyang Med Rev.
- 2013 May;33(2):110-117.
- doi: 10.7599/hmr.2013.33.2.110
Various proteomics and immunological methods including mass spectrometry combined with both liquid and 2-D PAGE, and immunodetection have been employed to identify and characterize nitrated proteins from pathological samples. Nitrosative... -
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- Etoposide Reduces Peroxynitrite-Induced Cytotoxicity via Direct Scavenging Effect
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Choi IY, Kim WK
- KMID: 1460705
- Exp Neurobiol.
- 2010 Sep;19(2):90-96.
- doi: 10.5607/en.2010.19.2.90
Previously, we reported that glucose-deprived astrocytes are more vulnerable to the cytotoxicity of peroxynitrite, the reaction product of nitric oxide and superoxide anion. The augmented vulnerability of glucose-deprived astrocytes to... -
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- Endothelial Dysfunction-Its Molecular Mechanism and Potential Implication in Therapy
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Kim CH
- KMID: 1895023
- Korean Circ J.
- 2006 Sep;36(9):609-611.
- doi: 10.4070/kcj.2006.36.9.609
Endothelial dysfunction is known to be early stage of atherosclerosis and its presence leads to poor prognosis. Recently many basic researchs were done to elucidate the basic mechanism related to... -
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- Quantitative Determination of Five Phenolic Peroxynitrite-scavengers in Nine Korean Native Compositae herbs
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Nugroho A, Lim SC, Karki S, Choi JS, Park HJ
- KMID: 2312890
- Nat Prod Sci.
- 2015 Sep;21(3):155-161.
- doi: 10.0000/nps.2015.21.3.155
Peroxynitrite (ONOO-)-scavenging activities of nine Compositae herbs consisting of three Ixeris, two Youngia, two Cirsium and one of each Lactuca and Taraxacum species were evaluated. The contents of their ONOO-... -
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- Increase of peroxynitrite production in the rat brain following transient forebrain ischemia
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Kim HJ, Kim SY
- KMID: 1606934
- Korean J Physiol Pharmacol.
- 2001 Jun;5(3):205-212.
It has been proposed that nitric oxide is involved in the pathogenesis of cerebral ischemia-reperfusion. Because superoxide production is also enhanced during reperfusion, the cytotoxic oxidant peroxynitrite could be formed, but it is... -
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- TRPV1 Activation in Primary Cortical Neurons Induces Calcium-Dependent Programmed Cell Death
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Song J, Lee JH, Lee SH, Park KA, Lee WT, Lee JE
- KMID: 2165442
- Exp Neurobiol.
- 2013 Mar;22(1):51-57.
- doi: 10.5607/en.2013.22.1.51
Transient receptor potential cation channel, subfamily V, member 1 (TRPV1, also known as vanilloid receptor 1) is a receptor that detects capsaicin, a pungent component of chili peppers, and noxious... -
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- The Role of Nitric Oxide in the Cataract Development: A Possible Mechanism of Lens Opacity
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Kim BG, Yoo YS, Kim HK
- KMID: 2109324
- J Korean Ophthalmol Soc.
- 2002 Apr;43(4):757-763.
PURPOSE: To assess the role of nitric oxide in the development of cataract by detection of nitrotyrosine, which is a reaction product of peroxynitrite with tyrosine. METHODS: We have collected aqueous... -
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- Effect of Nitric Oxide and Peroxynitrite in Mucociliary Transport Function of Experimental Otitis Media with Effusion
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Jeon EJ, Park YS, Chae S, Yeo SW, Chang KH, Park SY
- KMID: 2276026
- Korean J Otolaryngol-Head Neck Surg.
- 2003 Sep;46(9):720-726.
BACKGROUND AND OBJECTIVES: Nitric oxide (NO) is generally beneficial but potentially toxic to host. It has been suggested that NO is an important mediator in the pathogenesis of otitis media... -
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- Chemiluminescence Study of Pe roxynitrite in Experimental Autoimmune Uveitis
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Ko MS, Wu GS, Rao NA, Bae SR
- KMID: 2205845
- J Korean Ophthalmol Soc.
- 2000 Apr;41(4):825-830.
The purpose of this study is to evaluate the extent of peroxynitrite generation in the pool of radicals/oxidants from intraocular inflammation using luminol-dependent chemiluminescence(LDCL)method. S-antigen induced uveitis was produced in... -
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- Postischemic Treatment with Aminoguanidine Inhibits Peroxynitrite Production in the Rat Hippocampus Following Transient Forebrain Ischemia
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Choi YS, Yoon YH, Lee JE, Cho KO, Kim SY, Lee SB
- KMID: 1517030
- Korean J Physiol Pharmacol.
- 2004 Feb;8(1):1-5.
Transient forebrain ischemia results in the delayed neuronal death in the CA1 area of the hippocampus. The present study was performed to determine effects of aminoguanidine, a selective iNOS inhibitor,... -
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- Effects of Peroxynitrite on HSP 70 Expression in Cultured Normal Human Nasal Epithelial Cell
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Jang TY, Choi YS, Kim KS, Ko KJ, Kim TM
- KMID: 2131854
- J Rhinol.
- 2005 Nov;12(2):88-91.
BACKGROUND AND OBJECTIVES: Nitric Oxide (NO) is an endogenous mediator first characterized as an endothelium-derived relaxing factor. It is now recognized as a key mediator in many physiological process such... -
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- The Role of Nitric Oxide on Cataractogenesis in Uveitis Model Induced by Concanavalin A and Lipopolysaccharide
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Kim YJ, Kim IS, Kim JC, Shyn KH
- KMID: 2336898
- J Korean Ophthalmol Soc.
- 2000 Mar;41(3):562-572.
Nitric oxide[NO]plays a diverse role in many biological systems such as vascular, nervous and respiratory system. Recently, many studies have been performed to define the relationship between NO and physiological... -
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- The Reversible Y-Suture Lens Opacity Formation in Endotoxin Induced Uveitis Model
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Kwak IH, Kim JC, Ko YS, Kwon NS, Jeong JM
- KMID: 2336826
- J Korean Ophthalmol Soc.
- 1999 Apr;40(4):966-977.
The present study was undertaken to find out the role of NO on cataractogenesis in the experimenally-induced uveitis(EIU) model. Nitrite and nitrate, stable oxidative products of nitric oxide(NO), were measured... -
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- Effect of Nitric Oxide and Peroxynitrite ( ONOO- ) on the Apoptosis of Murine Bladder Tumor-2 Cell Line
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Park HC, Chung HT, Rim JS
- KMID: 1870527
- Korean J Urol.
- 1997 Feb;38(2):120-128.
Nitric oxide (NO) has been emerged as an important intracellular and intercellular regulatory molecule having functions as diverse vasodilatation, neural communication, and host defense. In the immune system, NO produced... -
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- Nitric oxide and peroxynitrite formation in nasal secretion after allergen challenge in the allergic rhinitis
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Kim KS, Jang TY, Jung DH, Park SK, Lee SJ, Kim BY, Kim J
- KMID: 2275752
- Korean J Otolaryngol-Head Neck Surg.
- 2001 Aug;44(8):827-832.
BACKGROUND AND OBJECTIVES: Recent evidence has shown that nitric oxide (NO) levels are increased in allergic rhinitis. However, the role of this molecule in the pathophysiology of allergic rhinitis is... -
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- Nitric Oxide-Mediated Neurotoxicity after Excimer Laser Photorefractive Keratectomy
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Joo MJ, Lee KJ, Shin KH, Kim JC
- KMID: 2205473
- J Korean Ophthalmol Soc.
- 1999 Mar;40(3):688-698.
The aim of this study was to evaluate neurotoxicity of Nitric oxide(NO) on cornea after excimer laser photorefractive keratectomy(PRK). PRK was performed on rabbit eyes. According to the time table,... -
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- Involvement of nitric oxide in post ischemic injury of rat island skin flap
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Um SC, Suzuki S, Nishimura , Kim YB, Yang SJ
- KMID: 2119418
- J Korean Soc Plast Reconstr Surg.
- 1998 Jul;25(5):769-775.
A free radical gas, nitric oxide NO), has many useful functions when produced under physiological conditions by neurons and endothelial cells. However, excess NO has been reported to exert cytotoxic... -
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