- Phytochemical Constituents of the Root Bark from Morus alba and Their Il-6 Inhibitory Activity
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Chang YS, Jin HG, Lee H, Lee DS, Woo ER
- KMID: 2459971
- Nat Prod Sci.
- 2019 Sep;25(3):268-274.
- doi: 10.20307/nps.2019.25.3.268
Morus alba L., known as white mulberry, is a medicinal plant belongs to family Moraceae. It has long been used commonly in Ayurvedic for the treatment of lung-heat, cough, asthma,... -
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- Diels-Alder Type Adducts from Hairy Root Cultures of Morus macroura
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Happyana N, Hakim EH, Syah YM, Kayser O, Juliawaty , Mujahidin , Ermayanti , Achmad SA
- KMID: 2459965
- Nat Prod Sci.
- 2019 Sep;25(3):233-237.
- doi: 10.20307/nps.2019.25.3.233
Three Diels-Alder type adducts, guangsangon E (1), chalcomoracin (2) and sorocein I (3) were isolated from hairy root cultures of Morus macroura. The structures of the isolated compounds (1 –... -
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- Anti-inflammatory effects of mulberry twig extracts on dextran sulfate sodium-induced colitis mouse model
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Cui X, Kim E
- KMID: 2444937
- J Nutr Health.
- 2019 Apr;52(2):139-148.
- doi: 10.4163/jnh.2019.52.2.139
PURPOSE: Ulcerative colitis is a common inflammatory bowel disease. Prolonged colitis can be a risk factor for the development of colorectal cancer. Mulberry twig (MT, Sangzhi), a dry branch of... -
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- Inhibition of endoplasmic reticulum stress in high-fat-diet-induced obese C57BL/6 mice: Efficacy of a novel extract from mulberry (Morus alba) leaves fermented with Cordyceps militaris
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Lee MR, Bae SJ, Kim JE, Song BR, Choi JY, Park JJ, Park JW, Kang MJ, Choi HJ, Choi YW, Kim KM, Hwang DY
- KMID: 2459307
- Lab Anim Res.
- 2018 Dec;34(4):288-294.
- doi: 10.5625/lar.2018.34.4.288
A few clues about correlation between endoplasmic reticulum (ER) stress and mulberry (Morus alba) leaves were investigated in only the experimental autoimmune myocarditis and streptozotocin-induced diabetes. To investigate whether a... -
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- Coating rice with mulberry leaves rich in deoxynojirimycin ameliorates hyperglycemia and dyslipidemia in C57BL/KsJ db/db mice
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Lee J, Lee HJ, Lee JJ
- KMID: 2448691
- Nutr Res Pract.
- 2018 Dec;12(6):469-478.
- doi: 10.4162/nrp.2018.12.6.469
BACKGROUND/OBJECTIVES: Mulberry leaf (ML) has been shown to have an inhibitory effect on α-glucosidase, and suppresses postprandial hyperglycemia, which may be related to its deoxynojirimycin (DNJ) content. This study was... -
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- Effect of Natural Extracts on Oral Care Probiotics Weissella cibaria CMU and Periodontal Pathogens
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Yeu JE, Kim HJ, Kang MS
- KMID: 2437336
- Int J Oral Biol.
- 2018 Dec;43(4):193-200.
- doi: 10.11620/IJOB.2018.43.4.193
The purpose of this study is to determine if natural extracts could be used as an additive in oral health food made with Weissella cibaria CMU (oraCMU). Natural extracts of... -
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- Lipolytic effect of novel extracts from mulberry (Morus alba) leaves fermented with Cordyceps militaris in the primary adipocytes derived from SD rats
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Lee MR, Kim JE, Yun WB, Choi JY, Park JJ, Kim HR, Song BR, Choi YW, Kim KM, Hwang DY
- KMID: 2391102
- Lab Anim Res.
- 2017 Sep;33(3):270-279.
- doi: 10.5625/lar.2017.33.3.270
Mulberry (Morus alba) leaves are known to have therapeutic effects on lipid metabolism including lipogenesis, lipolysis and hyperlipidemia. However, novel compounds with strong lipolytic ability among 27 extracts of the... -
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- Heavy Metals Biosorption from Aqueous Solution by Endophytic Drechslera hawaiiensis of Morus alba L. Derived from Heavy Metals Habitats
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El-Gendy M, Hassanein , Abd El-Hay Ibrahim H, Abd El-Baky DH
- KMID: 2385654
- Mycobiology.
- 2017 Jun;45(2):73-83.
- doi: 10.5941/MYCO.2017.45.2.73
The ability of dead cells of endophytic Drechslera hawaiiensis of Morus alba L. grown in heavy metals habitats for bioremoval of cadmium (Cd²âº), copper (Cu²âº), and lead (Pb²âº) in aqueous... -
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- The Immunomodulatory Activity of Mori folium, the Leaf of Morus alba L., in RAW 264.7 Macrophages In Vitro
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Kwon DH, Cheon JM, Choi EO, Jeong JW, Lee KW, Kim KY, Kim SG, Kim S, Hong SH, Park C, Hwang HJ, Choi YH
- KMID: 2367572
- J Cancer Prev.
- 2016 Sep;21(3):144-151.
- doi: 10.15430/JCP.2016.21.3.144
BACKGROUND: Immunoregulatory elements have emerged as useful immunotherapeutic agents against cancer. In traditional medicine, Mori folium, the leaf of Morus alba L. (Moraceae), has been used for various medicinal purposes;... -
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- The New Phytoformula Containing Morus alba, Schizandra sinensis and Asparagus cochinchinensis Inhibits Lung Inflammation in vitro and in vivo
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Jeong HG, Lee CW, Lee JH, Kim SJ, Kwon YS, Heo Y, Kim HP
- KMID: 2312925
- Nat Prod Sci.
- 2016 Mar;22(1):70-75.
- doi: 10.20307/nps.2016.22.1.70
A phytoformula containing the root barks of Morus alba, the fructus of Schizandra sinensis and the roots of Asparagus cochinchinensis (MSA) was prepared as a potential new herbal remedy, and... -
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- Postprandial hypoglycemic effects of mulberry twig and root bark in vivo and in vitro
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Park SY, Jin BR, Lee YR, Kim YJ, Park JB, Jeon YH, Choi SW, Kwon O
- KMID: 2158302
- J Nutr Health.
- 2016 Feb;49(1):18-27.
- doi: 10.4163/jnh.2016.49.1.18
PURPOSE: Our previous study demonstrated the hypoglycemic effects of mulberry (Morus alba L.) leaf and the underlying mechanisms. Here we explored the potency of mulberry twigs (TW) and root barks... -
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- Effects of quercetin derivatives from mulberry leaves: Improved gene expression related hepatic lipid and glucose metabolism in short-term high-fat fed mice
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Sun X, Yamasaki M, Katsube T, Shiwaku K
- KMID: 2313821
- Nutr Res Pract.
- 2015 Apr;9(2):137-143.
- doi: 10.4162/nrp.2015.9.2.137
BACKGROUND/OBJECTIVES: Mulberry leaves contain quercetin derivatives, which have the effects of reducing obesity and improving lipid and glucose metabolism in mice with obesity. It is not clear whether or not... -
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- Isolation And Development Of Quantification Method For Cyanidin-3-glucoside And Cyanidin-3-rutinoside In Mulberry Fruit By High-performance Countercurrent Chromatography And High-performance Liquid Chromatography
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Choi SJ, Jeon H, Lee CU, Yoon SH, Bae SK, Chin YW, Yoon KD
- KMID: 2409594
- Nat Prod Sci.
- 2015 Mar;21(1):20-24.
- doi: 10.0000/nps.2015.21.1.20
Cyanidin-3-glucoside (C3G) and cyanidin-3-rutinoside (C3R) were isolated by high-performance countercurrent chromatography (HPCCC) using a two-phase solvent system composed of tert-butyl methyl ether/n-butanol/acetonitrile/water/trifluoroacetic acid (1 : 3 : 1 : 5... -
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- An IgE-Mediated Allergic Reaction Caused by Mulberry Fruit
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Choi JH, Sim JK, Oh JY, Hur GY, Min KH, Lee SY, Shim JJ, Kang KH
- KMID: 2365549
- Allergy Asthma Immunol Res.
- 2015 Mar;7(2):195-198.
- doi: 10.4168/aair.2015.7.2.195
Mulberry (Morus spp.) is a widespread deciduous tree and its fruit is commonly eaten in Korea and eastern Asia. Some reports demonstrate that mulberry fruit is a food allergen in... -
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- Anti-adipogenic effect of mulberry leaf ethanol extract in 3T3-L1 adipocytes
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Yang SJ, Park NY, Lim Y
- KMID: 2313786
- Nutr Res Pract.
- 2014 Dec;8(6):613-617.
- doi: 10.4162/nrp.2014.8.6.613
BACKGROUND/OBJECTIVES: Adipogenesis is part of the cell differentiation process in which undifferentiated fibroblasts (pre-adipocytes) become mature adipocytes with the accumulation of lipid droplets and subsequent cell morphological changes. Several transcription... -
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- Antimicrobial Activity of Mulberry Leaf against Mutans Streptococci and Periodontopathogens
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Park SN, Lim YK, Cho E, Jo E, Park PS, Kook JK
- KMID: 2170788
- Int J Oral Biol.
- 2014 Dec;39(4):201-206.
- doi: 10.11620/IJOB.2014.39.4.201
This study investigated the antimicrobial activity of methanol extract of mulberry leaf against 16 strains of mutans streptococci and four species of periodontopathogens: Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, and... -
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- Effects of Morus alba L. and Natural Products Including Morusin on In Vivo Secretion and In Vitro Production of Airway MUC5AC Mucin
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Lee HJ, Ryu J, Park SH, Woo ER, Kim AR, Lee SK, Kim YS, Kim JO, Hong JH, Lee CJ
- KMID: 2320541
- Tuberc Respir Dis.
- 2014 Aug;77(2):65-72.
- doi: 10.4046/trd.2014.77.2.65
BACKGROUND: It is valuable to find the potential activity of regulating the excessive mucin secretion by the compounds derived from various medicinal plants. We investigated whether aqueous extract of the... -
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- Effect of combined mulberry leaf and fruit extract on liver and skin cholesterol transporters in high fat diet-induced obese mice
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Valacchi G, Belmonte G, Miracco C, Eo H, Lim Y
- KMID: 2313706
- Nutr Res Pract.
- 2014 Feb;8(1):20-26.
Obesity is an epidemic disease characterized by an increased inflammatory state and chronic oxidative stress with high levels of pro-inflammatory cytokines and lipid peroxidation. Moreover, obesity alters cholesterol metabolism with... -
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- Evaluation of General Toxicity and Genotoxicity of the Silkworm Extract Powder
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Heo HS, Choi JH, Oh JJ, Lee WJ, Kim SS, Lee DH, Lee HK, Song SW, Kim KH, Choi YK, Ryu KS, Kang BH
- KMID: 2317845
- Toxicol Res.
- 2013 Dec;29(4):263-278.
The silkworm extract powder contain 1-deoxynojirimycin (DNJ), a potent alpha-glycosidase inhibitor, has therapeutic potency against diabetes mellitus. Therefore, natural products containing DNJ from mulberry leaves and silkworm are consumed as... -
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- Oxidation of fatty acid may be enhanced by a combination of pomegranate fruit phytochemicals and acetic acid in HepG2 cells
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Kim JY, Ok E, Kim YJ, Choi KS, Kwon O
- KMID: 2313663
- Nutr Res Pract.
- 2013 Jun;7(3):153-159.
We investigated whether the combination of phytochemicals and acetic acid in the form of fruit vinegar provides an additive effect on changes of mRNA levels related to fatty acid oxidation... -
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