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Non-Vitamin K Oral Anticoagulants in Stroke Patients: Practical Issues

Malhotra K, Khunger M, Liebeskind DS

No abstract available.
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Diffusion-Weighted Imaging-Alone Endovascular Thrombectomy Triage in Acute Stroke: Simulating Diffusion-Perfusion Mismatch Using Machine Learning

Kim YC, Seo WK, Baek IY, Lee JE, Song HN, Chung JW, Kim CK, Oh K, Suh Si, Bang OY, Kim GM, Saver JL, Liebeskind DS

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Blood Pressure in Acute Ischemic Stroke

McManus M, Liebeskind DS

Hypertension is present in up to 84% of patients presenting with acute stroke, and a smaller proportion of patients have blood pressures that are below typical values in the context...
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Benign Oligemia Despite a Malignant MRI Profile in Acute Ischemic Stroke

Bang OY, Lee KH, Kim SJ, Liebeskind DS

BACKGROUND: It has recently been suggested that diffusion and perfusion MRI can identify subgroups likely to benefit or potentially be harmed by reperfusion therapies. CASE REPORT: We investigated serial MRI data...
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Recent updates in dyslipidemia management: perspectives in stroke-specific situation

Seo WK, Hosseini M, Bang OY, Liebeskind DS

Managing dyslipidemia in stroke is essential. During the past several decades, monumental changes in dyslipidemia management have occurred, resulting in improvement in outcomes of patients with cardiovascular disease (CVD). The...
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Prevalence and Associations of Dural Arteriovenous Fistulae in Cerebral Venous Thrombosis: Analysis of ACTION-CVT

Shoskes A, Shu L, Nguyen TN, Abdalkader M, Giles J, Amar J, Siegler JE, Henninger N, ElNazeir M, Kasab SA, Klein P, Heldner MR, Antonenko K, Psychogios M, Liebeskind DS, Field T, Liberman A, Esenwa C, Simpkins A, Li G, Frontera J, Kuohn L, Rothstein A, Khazaal O, Aziz Y, Mistry E, Khatri P, Omran SS, Zubair AS, Sharma R, Starke RM, Morcos JJ, Romano JG, Yaghi S, Asdaghi N

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Wall Shear Stress Associated with Stroke Occurrence and Mechanisms in Middle Cerebral Artery Atherosclerosis

Woo HG, Kim HG, Lee KM, Ha SH, Jo H, Heo SH, Chang Di, Liebeskind DS, Kim BJ

Background and Purpose Various mechanisms are involved in the etiology of stroke caused by atherosclerosis of the middle cerebral artery (MCA). Here, we compared differences in plaque nature and hemodynamic...
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Impact of Baseline Ischemia on Outcome in Older Patients Undergoing Endovascular Therapy for Acute Ischemic Stroke

Hwang YH, Kim YW, Kang DH, Kim YS, Liebeskind DS

BACKGROUND AND PURPOSE: The outcome for older stroke patients who undergo endovascular revascularization remains unsatisfactory. We aimed to determine the effect of the extent of baseline ischemia on outcome according...
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Decision-Making Visual Aids for Late, Imaging-Guided Endovascular Thrombectomy for Acute Ischemic Stroke

Moshayedi P, Liebeskind DS, Jadhav A, Jahan R, Lansberg M, Sharma L, Nogueira RG, Saver JL

Background and Purpose Speedy decision-making is important for optimal outcomes from endovascular thrombectomy (EVT) for acute ischemic stroke (AIS). Figural decision aids facilitate rapid review of treatment benefits and harms,...
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Cortical Thinning in High-Grade Asymptomatic Carotid Stenosis

Marshall RS, Liebeskind DS, III JH, Edwards LJ, Howard G, Meschia JF, Brott TG, Lal BK, Heck D, Lanzino G, Sangha N, Kashyap VS, Morales CD, Cotton-Samuel D, Rivera AM, Brickman AM, Lazar RM

Background and Purpose High-grade carotid artery stenosis may alter hemodynamics in the ipsilateral hemisphere, but consequences of this effect are poorly understood. Cortical thinning is associated with cognitive impairment in...
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Timing and Predictors of Recanalization After Anticoagulation in Cerebral Venous Thrombosis

Salehi Omran S, Shu L, Chang A, Parikh NS, Zubair AS, Simpkins AN, Heldner MR, Hakim A, Kasab SA, Nguyen T, Klein P, Goldstein ED, Vedovati MC, Paciaroni M, Liebeskind DS, Yaghi S, Cutting S

Background and Purpose Vessel recanalization after cerebral venous thrombosis (CVT) is associated with favorable outcomes and lower mortality. Several studies examined the timing and predictors of recanalization after CVT with...
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Borderzone Infarcts and Recurrent Cerebrovascular Events in Symptomatic Intracranial Arterial Stenosis: A Systematic Review and Meta-Analysis

Das S, Shu L, Morgan RJ, Shah A, Fayad FH, Goldstein ED, Chahien D, Maglinger B, Bokka SK, Owens C, Abbasi M, Kvernland A, Siegler JE, Grory BM, Nguyen TN, Furie K, Khatri P, Mistry E, Prabhakaran S, Liebeskind DS, Romano JG, Havenon Ad, Palaiodimou L, Tsivgoulis G, Yaghi S

Background and Purpose Intracranial arterial stenosis (ICAS)-related stroke occurs due to three primary mechanisms with distinct infarct patterns: (1) borderzone infarcts (BZI) due to impaired distal perfusion, (2) territorial infarcts...
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Outcome Prediction in Cerebral Venous Thrombosis: The IN-REvASC Score

Klein P, Shu L, Nguyen TN, Siegler JE, Omran SS, Simpkins AN, Heldner M, Havenon Ad, Aparicio HJ, Abdalkader M, Psychogios M, Vedovati MC, Paciaroni M, Martial Rv, Liebeskind DS, Sousa DAd, Coutinho JM, Yaghi S, the ACTION-CVT Study Group

Background We identified risk factors, derived and validated a prognostic score for poor neurological outcome and death for use in cerebral venous thrombosis (CVT). Methods We performed an international multicenter...
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Mechanical Thrombectomy Versus Intravenous Thrombolysis in Distal Medium Vessel Acute Ischemic Stroke: A Multinational Multicenter Propensity Score-Matched Study

Salim HA, Yedavalli V, Musmar B, Adeeb N, Essibayi MA, Naamani KE, Henninger N, Sundararajan SH, Kühn AL, Khalife J, Ghozy S, Scarcia L, Tan BY, Pulli B, Heit JJ, Regenhardt RW, Cancelliere NM, Bernstock JD, Rouchaud A, Fiehler J, Sheth S, Puri AS, Dyzmann C, Colasurdo M, Barreau X, Renieri L, Filipe JP, Harker P, Radu RA, Marotta TR, Spears J, Ota T, Mowla A, Jabbour P, Biswas A, Clarençon F, Siegler JE, Nguyen TN, Varela R, Baker A, Altschul D, Gonzalez NR, Möhlenbruch MA, Costalat V, Gory B, Stracke CP, Aziz-Sultan MA, Hecker C, Shaikh H, Liebeskind DS, Pedicelli A, Alexandre AM, Tancredi I, Faizy TD, Kalsoum E, Lubicz B, Patel AB, Pereira VM, Guenego A, Dmytriw AA, the MAD MT Investigators

Background and Purpose The management of acute ischemic stroke (AIS) due to distal medium vessel occlusion (DMVO) remains uncertain, particularly in comparing the effectiveness of intravenous thrombolysis (IVT) plus mechanical...
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