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10 results

Pathomorphological features of calcinosis circumscripta in a dog

Lee EM, Kim AY, Lee EJ, Jeong KS

  • Lab Anim Res.
  • 2016 Mar;32(1):74-77.
  • doi: 10.5625/lar.2016.32.1.74
A 19-month-old male German shepherd dog was presented with a hindlimb footpad mass. The mass was excised and histopathology was performed. Grossly, the cut section of the mass had multiple...
Rapid and efficient identification of the mouse leptin receptor mutation (C57BL/KsJ-db/db) by tetra-primer amplification refractory mutation system-polymerase chain reaction (ARMS-PCR) analysis

Jung H, Nam H, Suh JG

  • Lab Anim Res.
  • 2016 Mar;32(1):70-73.
  • doi: 10.5625/lar.2016.32.1.70
The C57BLKS/J-Lepr(db) mouse has a point mutation in the leptin receptor gene and is one of the most useful animal model for non-insulin dependent diabetes mellitus in human. Since the...
Anticoccidial effects of the Plantago asiatica extract on experimental Eimeria tenella infection

Hong S, Oh GW, Kang WG, Kim O

  • Lab Anim Res.
  • 2016 Mar;32(1):65-69.
  • doi: 10.5625/lar.2016.32.1.65
Anticoccidial effects of the Plantago asiatica extract (PAE) were evaluated in chickens following oral infection with Eimeria (E.) tenella. This study was conducted on the 3-day-old chickens (n=30). Those animals...
Comparison of the response using ICR mice derived from three different sources to ethanol/hydrochloric acid-induced gastric injury

Song SH, Kim JE, Go J, Koh EK, Sung JE, Lee HA, Choi KM, Kim HD, Jung YS, Kim KS, Hwang DY

  • Lab Anim Res.
  • 2016 Mar;32(1):56-64.
  • doi: 10.5625/lar.2016.32.1.56
Animal models for gastric ulcers produced by physical, pharmacological and surgical methods have been widely employed to evaluate therapeutic drugs and investigate the mechanism of action of this disease. ICR...
Reference values of hematology, biochemistry, and blood type in cynomolgus monkeys from cambodia origin

Choi K, Chang J, Lee MJ, Wang S, In K, Galano-tan WC, Jun S, Cho K, Hwang YH, Kim SJ, Park W

  • Lab Anim Res.
  • 2016 Mar;32(1):46-55.
  • doi: 10.5625/lar.2016.32.1.46
Cynomolgus monkeys as nonhuman primates are valuable animal models because they have a high level of human gene homology. There are many reference values for hematology and biochemistry of Cynomolgus...
Therapeutic effect of ethyl acetate extract from Asparagus cochinchinensis on phthalic anhydride-induced skin inflammation

Sung JE, Lee HA, Kim JE, Go J, Seo EJ, Yun WB, Kim DS, Son HJ, Lee CY, Lee HS, Hwang DY

  • Lab Anim Res.
  • 2016 Mar;32(1):34-45.
  • doi: 10.5625/lar.2016.32.1.34
Asparagus cochinchinensis has been used to treat various diseases including fever, cough, kidney disease, breast cancer, inflammatory disease and brain disease, while IL-4 cytokine has been considered as key regulator...
Role of mitogen-activated protein kinases and nuclear factor-kappa B in 1,3-dichloro-2-propanol-induced hepatic injury

Lee IC, Lee SM, Ko JW, Park SH, Shin IS, Moon C, Kim SH, Kim JC

  • Lab Anim Res.
  • 2016 Mar;32(1):24-33.
  • doi: 10.5625/lar.2016.32.1.24
In this study, the potential hepatotoxicity of 1,3-dichloro-2-propanol and its hepatotoxic mechanisms in rats was investigated. The test chemical was administered orally to male rats at 0, 27.5, 55, and...
Laxative effects of Liriope platyphylla are tightly correlated with suppression of endoplasmic reticulum stress in loperamide-induced constipation of SD rats

Kim JE, Go J, Sung JE, Lee HA, Seo EJ, Yun WB, Hwang DY

  • Lab Anim Res.
  • 2016 Mar;32(1):16-23.
  • doi: 10.5625/lar.2016.32.1.16
A dysfunction of endoplasmic reticulum (ER) stress response can result in various diseases, including cancer, inflammation, diabetes and neurodegenerative disorders. To investigate whether ER stress response can play an essential...
Cardiopulmonary effects of thiopental versus propofol as an induction agent prior to isoflurane anesthesia in chair trained rhesus macaques (Macaca mulatta)

Choi YJ, Park HJ, Kim HH, Lee YJ, Jung KC, Park SH, Lee JI

  • Lab Anim Res.
  • 2016 Mar;32(1):8-15.
  • doi: 10.5625/lar.2016.32.1.8
The purpose of this study was to evaluate the effects of thiopental versus propofol on cardiopulmonary functions, when used as an induction agent prior to isoflurane anesthesia in rhesus monkeys....
Postnatal changes in glucose transporter 3 expression in the dentate gyrus of the C57BL/6 mouse model

Jung HY, Yim HS, Yoo DY, Kim JW, Chung JY, Seong JK, Yoon YS, Kim DW, Hwang IK

  • Lab Anim Res.
  • 2016 Mar;32(1):1-7.
  • doi: 10.5625/lar.2016.32.1.1
In this study, we observed the ontogenetic changes in glucose transporter 3 (GLUT3) immunoreactivity, a major neuronal GLUT, in the dentate gyrus of mouse brains at various ages: postnatal day...

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