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Isolation of Flavonoid Glycosides with Cholinesterase Inhibition Activity and Quantification from Stachys japonica

Nugroho A, Choi JS, Seong SH, Song BM, Park KS, Park HJ

The three flavone glycosides, 4′-O-methylisoscutellarein 7-O-(6‴-O-acetyl)-β-D-allopyranosyl(1→2)-β-D-glucopyranoside (1), isoscutellarein 7-O-(6‴-O-acetyl)-β-D-allopyranosyl(1→2)-β-D-glucopyranoside (3), and isoscutellarein 7-O-β-D-allopyranosyl(1→2)-β-D-glucopyranoside (4) in addition to a flavonol glycoside, kaempferol 3-O-β-D-glucopyranoside (astragalin, 2), were isolated from Stachys japonica (Lamiaceae)....
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Identification and HPLC Quantification of a Phytoecdysone and Three Phenolic Glycosides in Lamium takesimense Nakai

Nugroho A, Park KS, Seo DJ, Park HJ

The herbs of Lamium takesimense Nakai (Lamiaceae) is used to treat spasmodic and inflammatory disease. The four polar compounds, ecdysterone, isoacteoside, rutin and lamiuside C, were isolated and identified from...
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Analysis of Essential oil, Quantification of Six Glycosides, and Nitric Oxide Synthase Inhibition Activity in Caryopteris incana

Nugroho A, Lee SK, Kim D, Choi JS, Park KS, Song BM, Park HJ

Caryopteris incana (Verbenaceae) has been used to treat cough, arthritis, and eczema in Oriental medicine. The two fractions (CHCl₃- and BuOH fractions) and the essential oil of the plant material...
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A New Steroidal Glycoside from Allium macrostemon Bunge

Kim YS, Cha JM, Kim DH, Lee TH, Lee KR

A phytochemical investigation of Allium macrostemon Bunge (Liliaceae) afforded the new pregnane steroidal glycoside, named allimacroside F (1), along with three known glycosides, benzyl-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside (2), phenylethyl-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside (3), (Z)-3-hexenyl-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside (4). The...
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HPLC analysis of Phenolic Substances and Anti-Alzheimer's Activity of Korean Quercus Species

Nugroho A, Song BM, Seong SH, Choi JS, Choi J, Choi JY, Park HJ

This study aimed to establish the quantitative method to analyze the content of peroxynitrite-scavengers belonging to polyphenols in six Korean Quercus species (Quercus mongolica, Q. dentata, Q. acutissima, Q. alienta,...
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Inhibitory Effect of Rotundarpene on Parkinsonian Neurotoxin 1-Methyl-4-Phenylpyridinium-Induced Apoptotic Cell Death

Han SW, Lee CS, Hwang IH, Han JH, Kim DE

BACKGROUND: The extract and hemiterpene glycosides of Ilex Rotunda Thunb exert antioxidant and anti-inflammatory effects. The effect of rotundarpene on apoptosis in neuronal cells caused by the 1-methyl-4-phenylpyridinium (MPP⁺) has...
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Pharmacological Activities and Applications of Spicatoside A

Ramalingam M, Kim SJ

Liriopogons (Liriope and Opiopogon) species are used as a main medicinal ingredient in several Asian countries. The Liriopes Radix (tuber, root of Liriope platyphylla) has to be a promising candidate...
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Differential Effects of Quercetin and Quercetin Glycosides on Human α7 Nicotinic Acetylcholine Receptor-Mediated Ion Currents

Lee BH, Choi SH, Kim HJ, Jung SW, Hwang SH, Pyo MK, Rhim H, Kim HC, Kim HK, Lee SM, Nah SY

Quercetin is a flavonoid usually found in fruits and vegetables. Aside from its antioxidative effects, quercetin, like other flavonoids, has a various neuropharmacological actions. Quercetin-3-O-rhamnoside (Rham1), quercetin-3-O-rutinoside (Rutin), and quercetin-3-(2(G)-rhamnosylrutinoside...
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Phenolic Compounds Isolated from Opuntia ficus-indica Fruits

Kim JW, Kim TB, Yang H, Sung SH

On the phytochemical investigation of a 70% ethanol extract of the fruits of Opuntia ficus-indica, (Cacataceae), we could result in the isolation of thirteen phenolic compounds including seven flavonoids (1...
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Bioconverted Jeju Hallabong tangor (Citrus kiyomi × ponkan) peel extracts by cytolase enhance antioxidant and anti-inflammatory capacity in RAW 264.7 cells

Chang YH, Seo J, Song E, Choi HJ, Shim E, Lee O, Hwang J

BACKGROUND/OBJECTIVES: Citrus and its peels have been used in Asian folk medicine due to abundant flavonoids and usage of citrus peels, which are byproducts from juice and/or jam processing, may...
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Flavonoid Glycosides from the Flowers of Pulsatilla koreana Nakai

Seo KH, Jung JW, Thi NN, Lee YH, Baek NI

Extraction and fractionation of Pulsatilla koreana flowers followed by, repeated open column chromatography for EtOAc and n-BuOH fractions yielded four flavonoid glycosides, namely, astragalin (1), tiliroside (2), buddlenoide A (3),...
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Comparative Evaluation of Hepatoprotective Activities of Geniposide, Crocins and Crocetin by CCl4-Induced liver Injury in Mice

Chen P, Chen Y, Wang Y, Cai S, Deng L, Liu J, Zhang H

Iridoid glycosides (mainly geniposide) and crocetin derivatives (crocins) are the two major active constituents in Gardenia jasminoides Ellis. In the present study, geniposide, crocins, crocin-1 and crocetin were separated from...
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Gastroprotective Activities of Sennoside A and Sennoside B via the Up-Regulation of Prostaglandin E2 and the Inhibition of H+/K+-ATPase

Hwang IY, Jeong CS

Sennoside A (erythro) and sennoside B (threo) are dianthrone glycosides and diastereomers. We investigated their abilities to prevent the gastric lesions associated with diseases, such as, gastritis and gastric ulcer....
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Phenolic Constituents from the Flowers of Hamamelis japonica Sieb. et Zucc.

Yim SH, Lee YJ, Park KD, Lee IS, Shin BA, Jung DW, Williams D, Kim HJ

Hamamelis japonica (Hamamelidaceae), widely known as Japanese witch hazel, is a deciduous flowering shrub that produces compact clumps of yellow or orange-red flowers with long and thin petals. As a...
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Anti-inflammatory Triterpenes and Glyceryl Glycosides from Kandelia candel (L.) Druce

Dat LD, Thao NP, Tai BH, Luyen BT, Yang SY, Kim S, Koo JE, Koh YS, Cuong NT, Nam NH, Thanh NV, Kiem PV, Minh CV, Kim YH

Phytochemical investigation of Kandelia candel resulted in the isolation of six triterpenes (1 - 5) and two glyceryl glycosides (6 and 7) and their structures were determined by comparing the...
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The Change of Ginsenoside Composition in the Ginseng (Panax ginseng) Flower Buds by the Ultrasonication and Vinegar Process

Gwak HH, Hong JT, Ahn CH, Kim KJ, Kim SG, Yoon SS, Im BO, Cho SH, Nam YM, Ko SK

The purpose of this study was to develop a new ginseng (Panax ginseng) flower buds extract with the high concentration of ginsenoside Rg3, Rg5, Rk1, Rh1 and F4, the Red...
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Chemical Constituents from the Aerial Parts of Bupleurum falcatum L. and Biological Evidences

Tung NH, Uto T, Morinaga O, Shoyama Y

In this study, phytochemical investigation on the aerial parts of Bupleurum falcatum resulted in the isolation of fourteen compounds including three quinic acid derivatives (1 - 3), five flavonoids (4...
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Fermented soybeans by Rhizopus oligosporus reduce femoral bone loss in ovariectomized rats

Yoo HW, Chang MJ, Kim SH

BACKGROUND/OBJECTIVES: Soy isoflavones are structurally similar to estrogen and bind to estrogen receptors, suggesting that they exhibit estrogenic activities; therefore, they are referred to as phytoestrogens. Fermentation may affect the...
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Delphinidin inhibits cell proliferation and induces apoptosis in MDA-MB-231 human breast cancer cell lines

Seo EY

  • KMID: 2327130
  • J Nutr Health.
  • 2013 Dec;46(6):503-510.
Breast cancer is the most common malignancy in women, both in the developed and developing countries. Anthocyanins are natural coloring of a multitude of foods, such as berries, grapes or...
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Determination of Cyanogenic Compounds in Edible Plants by Ion Chromatography

Cho HJ, Do BK, Shim SM, Kwon H, Lee DH, Nah AH, Choi YJ, Lee SY

  • KMID: 2317828
  • Toxicol Res.
  • 2013 Jun;29(2):143-147.
Cyanogenic glycosides are HCN-producing phytotoxins; HCN is a powerful and a rapidly acting poison. It is not difficult to find plants containing these compounds in the food supply and/or in...
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