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Potential Interaction of Plasmodium falciparum Hsp60 and Calpain

Yeo SJ, Liu DX, Park H

After invasion of red blood cells, malaria matures within the cell by degrading hemoglobin avidly. For enormous protein breakdown in trophozoite stage, many efficient and ordered proteolysis networks have been...
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Studies on the Effects of Monoclonal Antibodies to Mammalian Heat Shock Protein 60 (HSP 60) on Mouse Embryo Development In Vitro

Lee IH, Chung KN, Kim YB

  • KMID: 2272194
  • Korean J Obstet Gynecol.
  • 2003 Nov;46(11):2216-2220.
OBJECTIVE: To investigate the effects of antibodies to HSP 60 on the early mouse embryo development in vitro. METHODS: The 175 late 2-cell mouse embryos were obtained from 6-7 week...
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Identification of mono- or poly-specific monoclonal antibody to Porphyromonas gingivalis heat-shock protein 60

Choi J, Lee SY, Kim K, Choi BK, Kim MJ

  • KMID: 2329626
  • J Periodontal Implant Sci.
  • 2011 Apr;41(2):54-59.
PURPOSE: The aim of this study was to define the immunoreactive specificity of Porphyromonas gingivalis (P. gingivalis) heat shock protein (HSP) 60 in periodontitis and atherosclerosis. METHODS: In an attempt to...
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First Case of Mycobacterium longobardum Infection

Hong SK, Sung JY, Lee HJ, Oh MD, Park SS, Kim EC

Mycobacterium longobardum is a slow-growing, nontuberculous mycobacterium that was first characterized from the M. terrae complex in 2012. We report a case of M. longobardum induced chronic osteomyelitis. A 71-yr-old...
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The Expression of Heat Shock Protein 60 kDa in Tissues and Cell Lines of Breast Cancer

You BC, Park SY, Lee YD, Lee JN, Hwang YJ, Park HK

PURPOSE: Breast cancer has been reported as the most common cancer of women in the United States, Western Europe and Korea and about 210,000 and 10,000 women in United States...
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Species Identification of Coagulase Negative Staphylococci by Polymerase Chain Reaction-Restriction Fragment Length Polymorphism of Heat Shock Protein 60 Gene

oh EJ, Jang JD, Park YJ, Kim SM, Kim BK

  • KMID: 1533934
  • Korean J Clin Microbiol.
  • 2000 Mar;3(1):36-42.
BACKGROUND: An accurate and rapid method for specise identification of coagulase negative staphylococci(CNS) has been increasingly necessary for the clinical significance and planning the management of patients with staphylococcal infections....
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Production and characterization of cross-reactive anti-Porphyromonas gingivalis heat shock protein 60 monoclonal antibody

Choi JI, Kim SJ, Lee JY, Lee JY

PURPOSE: Porphyromonas gingivalis (P. gingivalis) heat shock protein (HSP)60 may play a role in the immunopathogenesis of periodontitis as well as atherosclerosis by modulating autoimmune reaction due to its high...
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Identification of proteins differentially expressed by glutamate treatment in cerebral cortex of neonatal rats

Kang JB, Park DJ, Koh PO

Glutamate leads to neuronal cell damage by generating neurotoxicity during brain development. The objective of this study is to identify proteins that differently expressed by glutamate treatment in neonatal cerebral...
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The Effect of 60-kDa Heat Shock Protein on Acute Experimental Pancreatitis

Lee G, Kim KH, Kim CD, Lee HS, Jeen YT, Chun HJ, Song CW, Um SH, Lee SW, Choi JH, Ryu HS, Hyun JH, Park IS

  • KMID: 1772571
  • Korean J Gastroenterol.
  • 1999 Dec;34(6):793-805.
BACKGROUND/AIMS: Recent studies showed that heat shock protein 60 (HSP60) might have a protective effect on experimental pancreatitis. However, protective mechanism of HSP60 is still unclear. The present study was...
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Heat Shock Protein 60 and 27 expressions on the trophoblast of preterm birth

Kim SY, Chung EJ, Oh HM, Kim JM, Min DL, Hwang YJ

  • KMID: 2273472
  • Korean J Obstet Gynecol.
  • 2008 Sep;51(9):957-964.
OBJECTIVE: To compare the distribution and expression of hsp60 and hsp27 in placental trophoblast between preterm and term placenta and to observe hsp immune response in relation to the pathogenesis...
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Molecular and phylogenetic analysis of Anaplasma spp. in sheep and goats from six provinces of China

Zhang Y, Lv Y, Zhang F, Zhang W, Wang J, Cui Y, Wang R, Jian F, Zhang L, Ning C

Members of the genus Anaplasma are important emerging tick-borne pathogens in both humans and animals in tropical and subtropical areas. Here, we investigated the presence of Anaplasma spp. in 621...
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A potent multivalent vaccine for modulation of immune system in atherosclerosis: an in silico approach

Karkhah A, Amani J

PURPOSE: Atherosclerosis is classically defined as an immune-mediated disease characterized by accumulation of low-density lipoprotein cholesterol over intima in medium sized and large arteries. Recent studies have demonstrated that both...
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Immune Responses Induced by HSP60 DNA Vaccine against Toxoplasma gondii Infection in Kunming Mice

Li ZY, Lu J, Zhang NZ, Chen J, Zhu XQ

Toxoplasma gondii can infect all the vertebrates including human, and leads to serious toxoplasmosis and considerable veterinary problems. T. gondii heat shock protein 60 (HSP60) is associated with the activation...
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Human CD103+ dendritic cells promote the differentiation of Porphyromonas gingivalis heat shock protein peptide-specific regulatory T cells

Kim MJ, Jeong EK, Kwon EY, Joo JY, Lee JY, Choi J

PURPOSE: Regulatory T cells (Tregs), expressing CD4 and CD25 as well as Foxp3, are known to play a pivotal role in immunoregulatory function in autoimmune diseases, cancers, and graft rejection....
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The Effect of Vero Cell Coculture on the Development of Mouse Embryos Exposed to Monoclonal Antibodies Specific for Mammalian Heat Shock Protein 60

Noh JH, Chung KN, Kim YB

Heat shock proteins (HSP) have been identified as an important factor of a very complex and highly conserved cellular defense mechanism to preserve cell survival under adverse environmental conditions. HSP...
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Etiopathology of Behcet's disease: immunological aspects

Sakane T, Suzuki N, Nagafuchi

Behcet's disease is recognized as a systemic inflammatory disease of unknown etiology. The disease has a chronic course with periodic exacerbations and progressive deterioration. Previous reports have shown at least...
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Prevalence of Anaplasma and Bartonella spp. in Ticks Collected from Korean Water Deer (Hydropotes inermis argyropus)

Kang JG, Ko S, Kim HC, Chong ST, Klein TA, Chae JB, Jo YS, Choi KS, Yu DH, Park BK, Park J, Chae JS

Deer serve as reservoirs of tick-borne pathogens that impact on medical and veterinary health worldwide. In the Republic of Korea, the population of Korean water deer (KWD, Hydropotes inermis argyropus)...
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Expression of Heat Shock Protein 60 kDa Is Upregulated in Cervical Cancer

Hwang YJ, Lee SP, Kim SY, Choi YH, Kim MJ, Lee CH, Lee JY, Kim DY

PURPOSE: Cervical cancer caused by the human papilloma virus (HPV) continues to be the cause of yearly death among women. However, it is a curable disease when diagnosed at an...
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Chronic Pulmonary Disease Due to Mycobacterium monacense Infection: The First Case from Iran

Shojaei H, Hashemi A, Heidarieh , Hosseini N, Daei Naser A

We herein report a case in which the recently characterized species Mycobacterium monacense was isolated from the sputum of an Iranian patient. This case represents the first isolation of M....
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