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Ischemic Stroke in Rats Enhances Bone Resorption in Vitro

Chung ME, Lee JI, Im S, Park JH

We hypothesized that the formation and differentialtion of osteoclasts are accelerated and the potential of bone resorption is increased in the hemiplegic bone marrow in the early stage of stroke....
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Role of Regulatory T Cells in Transferable Immunological Tolerance to Bone Marrow Donor in Murine Mixed Chimerism Model

Yoon IH, Kim YH, Kim YS, Shin JS, Park CG

Constructing a bone marrow chimera prior to graft transplantation can induce donor-specific immune tolerance. Mixed chimerism containing hematopoietic cells of both recipient- and donor-origin has advantages attributed from low dose...
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Clinical application of stem cells in liver diseases

Bae SH

Most liver diseases lead to hepatic dysfunction with organ failure. Liver transplantation is the best curative therapy, but it has some limitations such as donor shortage, possibility of rejection, and...
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Clinical Trials with Stem Cells in Digestive Diseases and Future Perspectives

Kim TI

Many techniques for isolation, expansion and handling of stem cells are being developed rapidly, and preclinical evidence has shown the possibility to use this technology for refractory diseases in the...
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Cardiac side population cells exhibit endothelial differentiation potential

Yoon J, Choi SC, Park CY, Shim WJ, Lim DS

  • KMID: 1090968
  • Exp Mol Med.
  • 2007 Oct;39(5):653-662.
Recent studies have shown that side population (SP) cells, isolated from adult myocardium, represent a distinct cardiac progenitor cell population that exhibits functional cardiomyogenic differentiation. However, information on the intrinsic...
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Maturation of bone marrow-derived dendritic cells by a novel beta-glucan purified from Paenibacillus polymyxa JB115

Ko EJ, Byon YY, Jee Y, Shin T, Park SC, Hahn TW, Joo HG

We investigated the immunostimulatory effects of a novel beta-glucan purified from Paenibacillus (P.) polymyxa JB115 on bone marrow-derived dendritic cells (DCs), a type of potent antigen-presenting cells. beta-glucan isolated from...
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Ameliorative Effect of Bone Marrow-Derived Stem Cells on Injured Liver of Mice Infected with Schistosoma mansoni

El-Mahdi M, Mansour WA, Hammam O, Mehana NA, Hussein TM

  • KMID: 1792162
  • Korean J Parasitol.
  • 2014 Apr;52(2):151-162.
The technique of stem cells or hepatocytes transplantation has recently improved in order to bridge the time before whole-organ liver transplantation. In the present study, unfractionated bone marrow stem cells...
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Comparing the osteogenic potential of canine mesenchymal stem cells derived from adipose tissues, bone marrow, umbilical cord blood, and Wharton's jelly for treating bone defects

Kang BJ, Ryu HH, Park SS, Koyama Y, Kikuchi M, Woo HM, Kim WH, Kweon OK

Alternative sources of mesenchymal stem cells (MSCs) for replacing bone marrow (BM) have been extensively investigated in the field of bone tissue engineering. The purpose of this study was to...
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Normalization of Red Cell Enolase Level Following Allogeneic Bone Marrow Transplantation in a Child with Diamond-Blackfan Anemia

Park JA, Lim YJ, Park HJ, Kong SY, Park BK, Ghim TT

We describe a girl with Diamond-Blackfan anemia with accompanying red cell enolase deficiency. At the age of 9 yr old, the patient received allogeneic bone marrow transplantation from her HLA-identical...
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The Effect of Simvastatin on the Proliferation and Differentiation of Human Bone Marrow Stromal Cells

Baek KH, Lee WY, Oh KW, Tae HJ, Lee JM, Lee EJ, Han JH, Kang MI, Cha BY, Lee KW, Son HY, Kang SK

Statins have been postulated to affect the bone metabolism. Recent experimental and epidemiologic studies have suggested that statins may also have bone protective effects. This study assessed the effects of...
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Neuron-Like Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells

Bae KS, Park JB, Kim HS, Kim DS, Park DJ, Kang SJ

PURPOSE: Mesenchymal stem cells (MSCs) are multipotent and give rise to distinctly differentiated cells from all three germ layers. Neuronal differentiation of MSC has great potential for cellular therapy. We...
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Direct and Indirect Effects of Androgens on Survival of Hematopoietic Progenitor Cells In Vitro

Kim SW, Hwang JH, Cheon JM, Park NS, Park SE, Park SJ, Yun HJ, Kim S, Jo DY

Androgens remain a common treatment for certain type of anemia, based upon its myelostimulating effects; however, it has not been established whether androgens affect apoptosis of hematopoietic progenitor cells (HPCs)....
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Combined Treatment of an Intratumoral Injection of Dendritic Cells and Systemic Chemotherapy (Paclitaxel) for Murine Fibrosarcoma

Choi GS, Lee MH, Kim SK, Kim CS, Lee HS, Im MW, Kil HY, Seong DH, Lee JR, Kim WC, Lee MG, Song SU

  • KMID: 2428301
  • Yonsei Med J.
  • 2005 Dec;46(6):835-842.
A novel combined treatment of conventional chemotherapy with an intratumoral injection of syngeneic dendritic cells (DCs) has emerged as a potent cancer treatment strategy. In this study, we evaluated the...
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Ethyl Acetate Fraction from Cudrania Tricuspidata Inhibits IL-1beta-Stimulated Osteoclast Differentiation through Downregulation of MAPKs, c-Fos and NFATc1

Lee EG, Yun HJ, Lee SI, Yoo WH

BACKGROUND/AIMS: The present study was performed to determine the effects of the ethyl acetate extract of Cudrania tricuspidata (EACT) on interleukin (IL)-1beta-stimulated receptor activator of NF-kappaB ligand (RANKL)-mediated osteoclast differentiation....
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Familial Hemophagocytic Lymphohistiocytosis Type 2 in a Korean Infant With Compound Heterozygous PRF1 Defects Involving a PRF1 Mutation, c.1091T>G

Kim MS, Cho YU, Jang S, Seo EJ, Im HJ, Park CJ

No abstract available.
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Effect of Endogenous Bone Marrow Derived Stem Cells Induced by AMD-3100 on Expanded Ischemic Flap

Jeong HS, Lee HK, Tark KC, Lew DH, Koh YW, Kim CH, Seo IS

The purpose of this study was to devise an expanded ischemic flap model and to investigate the role of AMD-3100 (Plerixafor, chemokine receptor 4 inhibitor) in this model by confirming...
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CD4+CD25highFoxP3+ Regulatory T-cells in Hematologic Diseases

Moon HW, Kim BH, Park CM, Hur M, Yun YM, Kim SY, Lee MH

BACKGROUND: CD4+CD25+ regulatory T-cells (Tregs) play a critical role in immune responses. We explored the status of Tregs in neoplastic and autoimmune hematologic diseases. We also evaluated the technical aspects...
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Spectrin Tunis (Sp alpha I/78) in a Korean Family with Hereditary Elliptocytosis

Han E, Kim A, Park J, Kim M, Kim Y, Han K, Kim YJ

No abstract available.
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Two Cases of Near-Tetraploidy in Acute Leukemias of Ambiguous Lineage

Kim BH, Kim HR, Lee MK, Chi H

No abstract available.
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Proangiogenic cells enhanced persistent and physiologic neovascularization compared with macrophages

Choi YE, Cha YR, Lee KM, Kim HJ, Yoon CH

Proangiogenic cells (PACs) display surface markers and secrete angiogenic factors similar to those used by myelomonocytic cells, but, unlike myelomonocytic cells, PACs enhance neovascularization activity in experimental ischemic diseases. This...
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