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Lipidomic analysis of plasma lipids composition changes in septic mice

Ahn WG, Jung JS, Song DK

A lipidomic study on extensive plasma lipids in bacterial peritonitis (cecal ligation and puncture, CLP)-induced sepsis in mice was done at 24 h post-CLP. The effects of administration of lysophosphatidylcholine...
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N-acetyl-L-cysteine and cysteine increase intracellular calcium concentration in human neutrophils

Hasan MA, Ahn WG, Song DK

N-acetyl-L-cysteine (NAC) and cysteine have been implicated in a number of human neutrophils' functional responses. However, though Ca²⁺ signaling is one of the key signalings contributing to the functional responses...
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Immunomodulatory effect of splenectomy in lung cancer mouse xenograft models receiving radiation therapy

Kim Y, Choi C, Park JH, Ahn WG, Shin SW, Kim SY, Noh JM

Purpose: This study aims to investigate the effect of splenectomy on radiation-mediated growth inhibition and immune modulation in lung cancer xenograft models. Materials and Methods: Human non-small cell lung cancer...
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Scant Extracellular NAD Cleaving Activity of Human Neutrophils is Down-Regulated by fMLP via FPRL1

Hasan MA, Sultan MT, Ahn WG, Kim YJ, Jang JH, Hong CW, Song DK

Extracellular nicotinamide adenine dinucleotide (NAD) cleaving activity of a particular cell type determines the rate of the degradation of extracellular NAD with formation of metabolites in the vicinity of the...
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Radiation-induced abscopal effect and its enhancement by programmed cell death 1 blockade in the hepatocellular carcinoma: A murine model study

Yoo GS, Ahn WG, Kim SY, Kang W, Choi C, Park HC

Background/Aims: The abscopal effect, a rare phenomenon induced by radiation, can be reinforced by immunotherapy. Although radiation therapy and immunotherapy are increasingly being utilized for the treatment of hepatocellular carcinoma...
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Protective effects of Acanthopanax divaricatus extract in mouse models of Alzheimer's disease

Yan JJ, Ahn WG, Jung JS, Kim HS, Hasan MA, Song DK

  • KMID: 2313754
  • Nutr Res Pract.
  • 2014 Aug;8(4):386-390.
BACKGROUND: Acanthopanax divaricatus var. albeofructus (ADA) extract has been reported to have anti-oxidant, immunomodulatory, and anti-mutagenic activity. MATERIALS/METHODS: We investigated the effects of ADA extract on two mouse models of Alzheimer's...
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The Amelioration Effect of the Ethanolic Extract of Cnidium officinale in Mice with Imiquimod-induced Psoriasis-like Skin Lesion

Lee YJ, Hong IK, Kim H, Heo SI, Kwon DJ, Ahn WG, Kim YH, Seo EJ, Han SI, Cho HJ, Kim SY, Yang H

Psoriasis is an auto-immune skin disease, which is characterized by the excessive generation of plaques on the skin with typically a long-lasting red, itchy and scaly symptoms. Imiquimod, which has...
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Targeted Liquid Biopsy Using Irradiation to Facilitate the Release of Cell-Free DNA from a Spatially Aimed Tumor Tissue

Noh JM, Kim YJ, Lee HY, Choi C, Ahn WG, Lee T, Pyo H, Park JH, Park D, Park WY

Purpose We investigated the feasibility of using an anatomically localized, target-enriched liquid biopsy (TLB) in mouse models of lung cancer. Materials and Methods After irradiating xenograft mouse with human lung cancer...
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