Blood Res.  2023 Dec;58(4):237-240. 10.5045/br.2023.2023185.

Successful recovery of poor graft function by administration of romiplostim in a multiple myeloma case with poor graft function following autologous stem cell transplantation

Affiliations
  • 1Departments of Hematology Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
  • 2Departments of Laboratory Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea


Figure

  • Fig. 1 Images of bone marrow at different time points: before autologous stem cell transplantation (ASCT, upper row: A–D); at 282 days after ASCT, when the patient was diagnosed with poor graft function (middle row: E–H); and at 138 weeks after initiation of romiplostim, demonstrating stringent complete response of multiple myeloma with no evidence of fibrosis or dyspoiesis (lower row: I–L). The first column (A, E, and I) presents bone marrow aspiration, magnified ×100; the second column (B, F, and J) illustrates bone marrow biopsy, magnified ×100; the third column (C, G, and K) shows kappa staining, magnified as ×40 to ×100; the fourth column (D, H, and L) shows lambda staining magnified ×40 to ×100.

  • Fig. 2 Dynamics of platelet count (unit, ×109/L) and absolute neutrophil count (unit, ×109/L) following aut-ologous hematopoietic stem cell transplant and the response to romiplostim.


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