Knee Surg Relat Res.  2020 Jun;32(2):e30. 10.1186/s43019-020-00050-7.

Preoperative vitamin D level does not affect the short-term functional outcome after total knee arthroplasty in elderly women

  • 1Department of Orthopedic Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea
  • 2Department of Orthopedic Surgery, Dongcheondongkang Hospital, Ulsan, South Korea
  • 3Department of Orthopedic Surgery, Seongnam Citizens Medical Center, 10, Sujeong-ro 171beon-gil, Sujeong-gu, Seongnam-si, Gyeonggi-do, 13290, South Korea


We aimed to evaluate the effect of vitamin D levels on the functional outcome of elderly women who underwent total knee arthroplasty (TKA).
Seven hundred and four patients (1013 knees) who underwent primary TKA were included in our retrospective study. Preoperative vitamin D levels were measured and the relationship analyzed between these and age, weight, height, body mass index, and bone mineral density. Two hundred and twenty patients (220 knees) who received unilateral TKA and were followed up for more than 1 year after operation were divided into two groups: Group 1, serum 25-hydroxyvitamin D3 (25(OH)D3) level < 20 ng/ml; and Group 2, 25(OH)D3 level ≥ 20 ng/ ml. Both groups were evaluated for the relationship between vitamin D levels and postoperative Visual Analogue Scale (VAS) score, Knee Society Knee Score (KSKS), Knee Society Function Score (KSFS), and Western Ontario and McMaster Universities Arthritis Index (WOMAC) score.
The number of vitamin D-deficient patients (< 20 ng/ml of serum 25(OH)D3 level) was 556 (79.0%). In the correlation analysis, the vitamin D level was negatively correlated with weight only (pConclusions
Vitamin D deficiency was highly prevalent in patients who underwent TKA. Vitamin D levels negatively correlated with weight. Low vitamin D level was not a risk factor for unsatisfactory TKA outcome in elderly women.


Vitamin D; Arthroplasty; Knee; Outcome assessment; Women
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