World J Mens Health.  2020 Jan;38(1):95-102. 10.5534/wjmh.180119.

Do Kimchi and Cheonggukjang Probiotics as a Functional Food Improve Androgenetic Alopecia? A Clinical Pilot Study

• Park DW
• Lee HS
• Shim MS
• Yum KJ
• Seo JT

• KMID: 2465414
• DOI: http://doi.org/10.5534/wjmh.180119

Abstract

PURPOSE
Probiotic supplementation demonstrates beneficial effects on serum lipid profiles. We hypothesized that probiotics could benefit patients presenting with alopecia, secondary to improved blood flow to the scalp.
MATERIALS AND METHODS
Our study included men with stage II to V patterns of hair loss based on the Hamilton-Norwood classification and women with stage I to III patterns of hair loss based on the Ludwig classification. All patients were administered 80 mL of Mogut® (a kimchi and cheonggukjang probiotic product) twice a day. Hair growth and numbers were measured using the Triple Scope System® (KC Technology, Korea) at baseline and after 1 and 4 months of administration of a kimchi and cheonggukjang probiotic product.
RESULTS
At baseline, the mean hair count was 85.98±20.54 hairs/cm2 and the mean thickness was 0.062±0.011 mm in all patients (n=46). Hair count and thickness had significantly increased at 1 month (90.28±16.13 hairs/cm2 and 0.068±0.008 mm, respectively) and at 4 months (91.54±16.29 hairs/cm2 and 0.066±0.009 mm, respectively). In this study, we found that a kimchi and cheonggukjang probiotic product could promote hair growth and reverse hair loss without associated adverse effects such as diarrhea.
CONCLUSIONS
We suggest that the observed improvements in hair count and thickness resulted from initiation of the anagen phase in hair follicles in response to probiotics.

Keyword

Alopecia; Functional food; Leuconostoc; Probiotics; Scalp; Soybeans

MeSH Terms

Alopecia*
Classification
Diarrhea
Female
Functional Food*
Hair
Hair Follicle
Humans
Leuconostoc
Male
Pilot Projects*
Probiotics*
Scalp
Soybeans

Figure

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  Fig. 1 Results of all patients at 1 month.

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  Fig. 2 Results of all patients at 4 months.

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  Fig. 3 Results by sex at 1 month.

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  Fig. 4 Results by sex in 4 months.

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  Fig. 5 Response to administration of a kimchi and cheonggukjang probiotic product at baseline (0 month) and 4 months were measured by the Triple Scope System® (×20 magnification).

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