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Do Kimchi and Cheonggukjang Probiotics as a Functional Food Improve Androgenetic Alopecia? A Clinical Pilot Study

Park DW, Lee HS, Shim MS, Yum KJ, Seo JT

PURPOSE: Probiotic supplementation demonstrates beneficial effects on serum lipid profiles. We hypothesized that probiotics could benefit patients presenting with alopecia, secondary to improved blood flow to the scalp. MATERIALS AND METHODS:...
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Hair Follicle Nevus Located on the Neck: Comparison with Accessory Tragus, Cervical Chondrocutaneous Branchial Remnants and Trichofolliculoma

Lee JS, Yang JH, Park H, Yoon HS, Cho S

Hair follicle nevus (HFN) is a rare, benign, follicular hamartoma that most frequently presents as a congenital nodule on the face. We experienced a rare case of HFN on the...
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Expression Pattern and Role of Klotho in Human Hair Follicles

Jin XH, Pi LQ, Lee WS

BACKGROUND: Klotho protein plays a pivotal role in aging regulation. However, it is unclear whether klotho is expressed in human hair follicles and is correlated with hair growth. OBJECTIVE: The purpose...
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Melandrium firmum Extract Promotes Hair Growth by Modulating 5α-Reductase Activity and Gene Expression in C57BL/6J Mice

Huang B, Kang BG, Lim SS, Zhang XH

BACKGROUND: In our preliminary study, we screened for their potential to inhibit 5α-reductase, and Melandrium firmum (MF) extract showed the most potent activity as confirmed by high-performance liquid chromatography (HPLC). OBJECTIVE:...
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Clinco-pathologic Features of Alopecia in a Patient of Cronkhite-Canada Syndrome

Seong GH, Shon U, Park MJ, Park M, Hong SP, Kim MH, Park BC

  • KMID: 2457691
  • Korean J Dermatol.
  • 2019 Aug;57(7):391-394.
Although hair loss in Cronkhite-Canada syndrome (CCS) developed frequently, its exact mechanism has not been elucidated. Thus, we attempted to investigate the histopathologic features of hair loss with scalp biopsy...
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Birt-Hogg-Dubé Syndrome Associated with a Renal Tumor

Oh SJ, Hwang KE, Jeong ET, Kim HR, Choi KH, Ryu DW

Birt-Hogg-Dubé syndrome (BHD) is a rare autosomal dominant disorder characterized by the formation of hair follicle tumors, kidney tumors, and pulmonary cysts with recurrent spontaneous pneumothorax. A 44-year-old woman visited...
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The Significance of NOTCH Pathway in the Development of Fibrosis in Systemic Sclerosis

Zmorzyński S, Styk W, Filip AA, Krasowska

Systemic sclerosis (SSc) is an autoimmune disorder characterized by the fibrosis of skin, heart, lung, and kidney as well. Excessive activation of fibroblasts is associated with higher expression of Notch1...
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Udenafil Induces the Hair Growth Effect of Adipose-Derived Stem Cells

Choi N, Sung JH

Udenafil, which is a PDE5 inhibitor, is used to treat erectile dysfunction. However, it is unclear whether udenafil induces hair growth via the stimulation of adipose-derived stem cells (ASCs). In...
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Inhibition of Insulin-Like Growth Factor-1–Induced Sebum Production by Bilobetin in Cultured Human Sebocytes

Wang C, Hwang YL, Li XM, Kim SJ, Zhu MJ, Lee JH, Jiang RH, Kim CD

BACKGROUND: Sebocytes are the major cells of sebaceous gland. The essential role of sebocytes is the production of sebum, a specific lipid mixture, that covers the body surface and provides...
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Comparison of postoperative pain according to the harvesting method used in hair restorative surgery

Kim YS, Na YC, Park JH

BACKGROUND: Postoperative pain is one of the most common concerns of patients undergoing hair transplantation surgery. Because most patients are satisfied with the cosmetic improvement after transplantation, amelioration of postoperative...
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Metformin, an Activator of AMPK, Promotes the Growth of Hair Follicles via the AMPK/β-catenin Signaling Pathway

Moon HR, Park KY, Kang HJ, Lee WJ, Won CH, Chang SE, Lee MW, Choi JH, Park GH

  • KMID: 2449198
  • Korean J Dermatol.
  • 2019 May;57(4):175-181.
BACKGROUND: AMP-activated protein kinase (AMPK) is a serine/threonine protein kinase that plays a pivotal role in the balance of cellular energy metabolism. Recent studies have reported that AMPK has numerous...
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A prospective, comparative evaluation of axillary hair removal with an 808-nm diode laser at different fluences

Kang HY, Park ES, Nam SM

BACKGROUND: Diode lasers are the gold standard for removing unwanted hair. Lowering the energy should result in less pain and could theoretically affect therapeutic efficacy. This study evaluated the efficacy...
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Closure of a full-thickness scalp burn that occurred during hair coloring using a simple skin-stretching method: A case report and review of the literature

Oh SJ

Full-thickness scalp burns secondary to hair coloring are rare; however, such defects can be large and complex reconstruction of hair-bearing tissue may be necessary. Many skin-stretching devices that use gradual...
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Hair transplantation in patients with hair loss or scar deformity in the side hairline after midfacelifting surgery

Kim YS, Na YC, Park JH

BACKGROUND: Successful aesthetic plastic surgery is devoid of both unsightly scarring and postoperative disfigurement. Patients undergoing midface-lifting surgery are very often disconcerted by an altered side hairline, including sideburns, despite...
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Vitiligo with Leukotrichia Following Topical Diphenylcyclopropenone Immunotherapy for Acute Diffuse and Total Alopecia

Park JB, Seong SH, Jang JY, Yang MH, Kim JH, Suh KS, Sim WY, Jang MS

  • KMID: 2440729
  • Korean J Dermatol.
  • 2019 Feb;57(2):94-96.
Leukotrichia is defined as depigmentation of hair within vitiligo macules and is considered indicative of the destruction of the melanocyte reservoir within the hair follicle. A 15-year-old woman with acute...
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A Clinical and Histopathological Review of Chronic Cutaneous Lupus Erythematosus Alopecia in Korea

Chae MH, Lee JY, Yoon TY

  • KMID: 2440724
  • Korean J Dermatol.
  • 2019 Feb;57(2):66-75.
BACKGROUND: Chronic cutaneous lupus erythematosus (CCLE) often affects the scalp and results in alopecic lesions. To date, no studies have examined CCLE alopecia in Korea. OBJECTIVE: The aim of this study...
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Forehead-supporting chair system for follicular unit extraction hair transplantation

Park JH, You SH, Kim NR

The seated and prone positions are the most common surgical positions used during follicular unit extraction (FUE). Compared to the latter, the former eases centering and enables more optimal surgical...
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Anti-tuberculosis Drugs-induced Anagen Effluvium with Generalized Drug Eruption

Lim C, Park KD, Seo YJ, Lee J, Lee Y

  • KMID: 2433638
  • Korean J Dermatol.
  • 2019 Jan;57(1):15-19.
Anagen effluvium is an abrupt loss of hair in its growing phase due to an event that impairs the mitotic or metabolic activity of the hair follicle. Anagen effluvium is...
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A giant trichoblastic carcinoma

Lee JS, Kwon JH, Jung GS, Lee JW, Yang JD, Chung HY, Cho BC, Choi KY

Trichoblastic carcinoma usually occurs as a malignant transformation of the trichoblastoma, but is very rare. A 25-year-old man was admitted with trichoblastoma in the nuchal area with frequent recurrences since...
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Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth

Bak DH, Choi MJ, Kim SR, Lee BC, Kim JM, Jeon ES, Oh W, Lim ES, Park BC, Kim MJ, Na J, Kim BJ

Human umbilical cord blood mesenchymal stem cells (hUCB-MSCs) are used in tissue repair and regeneration; however, the mechanisms involved are not well understood. We investigated the hair growth-promoting effects of...
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