Pediatr Infect Vaccine.  2019 Aug;26(2):118-123. 10.14776/piv.2019.26.e14.

Postinfectious Glomerulonephritis Associated with Pneumococcus and Influenza A Virus Infection in a Child: a Case Report and Literature Review

Affiliations
  • 1Department of Pediatrics, Seoul National University Children's Hospital, Seoul, the Republic of Korea. pedwilly@snu.ac.kr
  • 2Department of Pediatrics, Seoul National University College of Medicine, Seoul, the Republic of Korea.
  • 3Department of Pediatrics, Chungbuk National University Hospital, Cheongju, the Republic of Korea.

Abstract

Postinfectious glomerulonephritis (PIGN) is most commonly caused by Streptococcus pyogenes in children, but PIGN associated with other pathogens has been described in the literature. A previously healthy 6-year-old boy was admitted with complaints of cough, fever, and right chest pain. The patient was diagnosed with pneumococcal bacteremia and influenza A virus infection and treated with antibiotics and antiviral agent. During hospitalization, generalized edema, hematuria, proteinuria, and increased blood pressure were observed; therefore, we started administering diuretics. The boy was discharged with gross hematuria, and even microscopic hematuria disappeared 14 weeks after discharge. We report a case of PIGN associated with bacteremic pneumococcal pneumonia and influenza A virus infection in children. A urine test and blood pressure measurement should be considered for the early detection of PIGN in children with pneumococcal or influenza A virus infection when they present with nephritic symptoms.

Keyword

Streptococcus pneumoniae; Glomerulonephritis; Influenza; Pneumonia; Children
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