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Association Between Air Pollution and Viral Infection in Severe Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Choi J, Shim JJ, Lee MG, Rhee CK, Joo H, Lee JH, Park HY, Kim WJ, Um SJ, Kim DK, Min KH

Background: Respiratory pathogen infections and air pollution are main causes of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Air pollution has a direct effect on the airway epithelial barrier...
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Incidence, Severity, and Mortality of Influenza During 2010–2020 in Korea: A Nationwide Study Based on the Population-Based National Health Insurance Service Database

Hwang SH, Lee H, Jung M, Kim SH, Sung HK, Oh Md, Lee JY

Background: The epidemiology of influenza is commonly used to understand and establish relevant health policies for emerging respiratory infections, including coronavirus disease 2019 (COVID-19). However, Korea has no confirmed nationwide...
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Coinfection between influenza and COVID-19 in neonates: A case report

Kang MJ, Yoon Y, Je BK, Kim YK, Seo WH

Coinfection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with other respiratory pathogens may complicate diagnosis and treatment. Since the risk of coinfection with SARS-CoV-2 is expected to increase during...
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HPAI-resistant Ri chickens exhibit elevated antiviral immune-related gene expression

Vu TH, Heo J, Hong Y, Kang S, Thanh Tran HT, Dang HV, Truong AD, Hong YH

Background: Highly pathogenic avian influenza viruses (HPAIVs) is an extremely contagious and high mortality rates in chickens resulting in substantial economic impact on the poultry sector. Therefore, it is necessary...
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Current situation and control strategies of H9N2 avian influenza in South Korea

Sagong M, Lee KN, Lee EK, Kang H, Choi YK, Lee YJ

The H9N2 avian influenza (AI) has become endemic in poultry in many countries since the 1990s, which has caused considerable economic losses in the poultry industry. Considering the long history...
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Development of reverse-transcription loop-mediated isothermal amplification assays for point-of-care testing of human influenza virus subtypes H1N1 and H3N2

Kang JS, Seo MR, Chung YJ

Influenza A virus (IAV) is the most widespread pathogen causing human respiratory infections. Although polymerase chain reaction (PCR)–based methods are currently the mostcommonly used tools for IAV detection, PCR is...
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A Cluster of Health Symptoms After a Law Enforcement Operation: A Case Study

Chiu SK, Hornsby-Myers J, Iverson C, Trout D

Law enforcement officers (LEOs) often encounter rapidly changing and uncontrolled situations that expose them to various hazards. A law enforcement agency requested an evaluation by the National Institute for Occupational...
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Elucidating the characteristics of Mx1 and resistance to influenza A virus subtype H1N1 in the newly developed KWM/Hym mice

Nam H, Kim B, Gautam A, Kim YY, Park ES, Lee JS, Kwon HJ, Seong JK, Suh JG

Background: Inbred mice have several advantages, including genetic similarity to humans, a well-established gene manipulation system, and strong tolerance to inbreeding. However, inbred mice derived from a limited genetic pool...
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Respiratory Syncytial Virus Outbreak Without Influenza in the Second Year of the Coronavirus Disease 2019 Pandemic: A National Sentinel Surveillance in Korea, 2021–2022 Season

Kim JH, Kim HY, Lee M, Ahn JG, Baek JY, Kim MY, Huh K, Jung J, Kang JM

Background: This study aimed to investigate whether respiratory syncytial virus (RSV) and influenza virus (IFV) infections would occur in 2021–2022 as domestic nonpharmaceutical interventions (NPIs) are easing. Methods: Data were collected...
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Analysis of risk factors between influenza and the occurrence of complicated influenza

Oh WH, Lee SH, Jang TC, Kim GM, Seo YW, Ko SH

  • KMID: 2532465
  • J Korean Soc Emerg Med.
  • 2022 Jun;33(3):304-313.
Objective: Influenza is an acute, respiratory viral disease, and may lead to complications such as pneumonia, which presents with significant morbidity and mortality. Previous studies did not have sufficient data...
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Genome characterization and mutation analysis of human influenza A virus in Thailand

Rattanaburi S, Sawaswong V, Nimsamer P, Mayuramart O, Sivapornnukul P, Khamwut A, Chanchaem P, Kongnomnan K, Suntronwong N, Poovorawan Y, Payungporn S

The influenza A viruses have high mutation rates and cause a serious health problem worldwide. Therefore, this study focused on genome characterization of the viruses isolated from Thai patients based...
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Vaccination in Pregnancy

Kim MA, Kim YH

Pregnant women and newborns are vulnerable to several pathogens and are at high risk of exposure to various infectious diseases. Part of this increased susceptibility in pregnant women is due...
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Effects of Non-Pharmacological Interventions on Respiratory Viruses Other Than SARS-CoV-2: Analysis of Laboratory Surveillance and Literature Review From 2018 to 2021

Shi HJ, Kim NY, Eom SA, Kim-Jeon MD, Oh SS, Moon BS, Kwon MJ, Eom JS

Background: Since the global coronavirus disease 2019 (COVID-19) pandemic, nonpharmacological interventions (NPIs) such as extensive and comprehensive hand hygiene, mask-wearing, and social distancing have been implemented globally. This study aimed...
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Impact of inland waters on highly pathogenic avian influenza outbreaks in neighboring poultry farms in South Korea

Ahmad S, Koh K, Yoo D, Suh G, Lee J, Lee CM

Background: Since 2003, the H5 highly pathogenic avian influenza (HPAI) subtype has caused massive economic losses in the poultry industry in South Korea. The role of inland water bodies in...
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The Emergence and Development of Hygienic Masks in Colonial Korea

HYUN J

This paper examines the social life of masks in colonial Korea with a focus on their use in hygienic practices. It argues that masks first appeared in the disease control...
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Improving siRNA design targeting nucleoprotein gene as antiviral against the Indonesian H5N1 virus

Hartawan R, Pujianto DA, Dharmayanti NLPI, Soebandrio A

Background: Small interfering RNA technology has been considered a prospective alternative antiviral treatment using gene silencing against influenza viruses with high mutations rates. On the other hand, there are no reports...
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Responses against infectious disease pandemics: a narrative review on COVID-19 A narrative review

Chung DR

Currently, the world is facing the coronavirus disease 2019 (COVID-19) pandemic. With this, an emerging infectious disease pandemic in the absence of effective antiviral agents and vaccines for a novel...
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Evaluation of Three Multiplex Realtime Reverse Transcription PCR Assays for Simultaneous Detection of SARS-CoV-2, Influenza A/B, and Respiratory Syncytial Virus in Nasopharyngeal Swabs

Yun J, Park JH, Kim N, Roh EY, Shin S, Yoon JH, Kim TS, Hyunwoong H

Background: In the coronavirus disease 2019 (COVID-19) pandemic era, the simultaneous detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza virus (Flu), and respiratory syncytial virus (RSV) is important...
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Evaluation of the AccuPower® RV1 Real-Time RT-PCR Kit and the AccuPower® RV1 Multiplex Kit for SARS-CoV-2 and Influenza Virus Detection

Kim MJ, Park H, Jeon YL, Shin HS, Cho SI, Kim B, Lee JS, Park SS, Seong MW

Background: The AccuPower® RV1 Real-Time RT-PCR Kit (Bioneer, Korea) and AccuPower® RV1 Multiplex Kit (Bioneer) are one-step real-time reverse transcription PCR assays for detecting severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)...
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A “Prime and Deploy” Strategy for Universal Influenza Vaccine Targeting Nucleoprotein Induces Lung-Resident Memory CD8 T cells

Chung H, Kim EA, Chang J

Lung-resident memory T cells (TRM ) play an essential role in protecting against pulmonary virus infection. Parenteral administration of DNA vaccine is generally not sufficient to induce lung CD8 T...
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