J Breast Cancer.  2018 Dec;21(4):343-353. 10.4048/jbc.2018.21.e47.

Current Approaches in Development of Immunotherapeutic Vaccines for Breast Cancer

• Allahverdiyev A
• Tari G
• Bagirova M
• Abamor ES

• KMID: 2429812
• DOI: http://doi.org/10.4048/jbc.2018.21.e47

Abstract

Cancer is the leading cause of death worldwide. In developed as well as developing countries, breast cancer is the most common cancer found among women. Currently, treatment of breast cancer consists mainly of surgery, chemotherapy, hormone therapy, and radiotherapy. In recent years, because of increased understanding of the therapeutic potential of immunotherapy in cancer prevention, cancer vaccines have gained importance. Here, we review various immunotherapeutic breast cancer vaccines including peptide-based vaccines, whole tumor cell vaccines, gene-based vaccines, and dendritic cell vaccines. We also discuss novel nanotechnology-based approaches to improving breast cancer vaccine efficiency.

Keyword

Breast neoplasms; Immunology; Immunotherapy; Vaccines

MeSH Terms

Allergy and Immunology
Breast Neoplasms*
Breast*
Cancer Vaccines
Cause of Death
Dendritic Cells
Developing Countries
Drug Therapy
Female
Humans
Immunotherapy
Radiotherapy
Vaccines*
Cancer Vaccines
Vaccines