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Heterogeneity of Human γδ T Cells and Their Role in Cancer Immunity

Lee HW, Chung YS, Kim TJ

The γδ T cells are unconventional lymphocytes that function in both innate and adaptive immune responses against various intracellular and infectious stresses. The γδ T cells can be exploited as...
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Asia Pacific Association of Allergy Asthma and Clinical Immunology White Paper 2020 on climate change, air pollution, and biodiversity in Asia-Pacific and impact on allergic diseases

Pawankar R, Wang JY, Wang IJ, Thien F, Chang YS, Latiff AH, Fujisawa T, Zhang L, Thong BY, Chatchatee P, Leung TF, Kamchaisatian W, Rengganis , Yoon HJ, Munkhbayarlakh S, Recto MT, Neo AG, Le Pham D, Lan LT, Davies JM, Oh JW

Air pollution, climate change, and reduced biodiversity are major threats to human health with detrimental effects on a variety of chronic noncommunicable diseases in particular respiratory and cardiovascular diseases. The...
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Report of the Korean Association of External Quality Assessment Service on Complement and Immunoglobulin (2018)

Kim KH

In 2018, the complement and immunoglobulin proficiency testing program of the Korean Association of External Quality Assessment Service included complement, free light chain, immunoglobulin, and anti-cyclic citrullinated peptide (anti-CCP). Tests...
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Scientific Hypotheses: Writing, Promoting, and Predicting Implications

Gasparyan , Ayvazyan L, Mukanova U, Yessirkepov M, Kitas GD

Scientific hypotheses are essential for progress in rapidly developing academic disciplines. Proposing new ideas and hypotheses require thorough analyses of evidence-based data and predictions of the implications. One of the...
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Immune-related Adverse Events: Overview and Management Strategies for the Use of Immune Checkpoint Inhibitors

Jeung HC, Oh SE, Kim JH

Recent studies on T cell immunology have been instrumental in developing therapies to overcome cancer immune escape, and immune checkpoint inhibitors have emerged as one of the most promising therapeutic...
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Therapeutic Effect of Glucosamine on an Atopic Dermatitis Animal Model

Yoon HS, Byun JW, Shin J, Kim YH, Choi GS

BACKGROUND: Recent studies have reported that glucosamine (GlcN) showed therapeutic effects in allergic diseases such as asthma and rhinitis, and its mechanisms include the suppression of T helper type 2...
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Evaluation of high resolution computed tomography findings of cystic fibrosis

Sasihuseyinoglu AS, Altıntaş DU, Soyupak S, Dogruel D, Yılmaz M, Serbes M, Duyuler G

BACKGROUND/AIMS: Morphological changes due to lung disease in patients with cystic fibrosis (CF) were evaluated using high resolution computed tomography (HRCT), and the HRCT scores obtained using the Bhalla scoring...
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Age-related Autoimmune Changes in Lacrimal Glands

de Souza R, de Paiva C, Alves MR

Aging is a complex process associated with dysregulation of the immune system and low levels of inflammation, often associated with the onset of many pathologies. The lacrimal gland (LG) plays...
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Characteristics of Adult Severe Refractory Asthma in Korea Analyzed From the Severe Asthma Registry

Kim MH, Kim SH, Park SY, Ban GY, Kim JH, Jung JW, Moon JY, Song WJ, Kwon HS, Kwon JW, Lee JH, Kang HR, Park JS, Kim TB, Park HW, Yoo KH, Oh YM, Koh YI, Jang AS, Lee BJ, Cho YJ, Cho SH, Park HS, Park CS, Yoon HJ, Cho YS

PURPOSE: Although mild to moderate asthma is much more common, the morbidity and mortality of severe asthma are much higher. This study was performed to identify and analyze the clinical...
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Current Approaches in Development of Immunotherapeutic Vaccines for Breast Cancer

Allahverdiyev A, Tari G, Bagirova M, Abamor ES

Cancer is the leading cause of death worldwide. In developed as well as developing countries, breast cancer is the most common cancer found among women. Currently, treatment of breast cancer...
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Centennial History of Yonsei University Dermatology in Korea: 1917 to 2017

Kim J, Kim TG, Lee SH, Lee MK, Kim JH, Lee SE, Kim DY, Roh MR, Park CO, Lee JH, Lee MG, Bang D, Oh SH, Chung KY

Yonsei Dermatology celebrated its centennial in 2017, marking 100 years since Kung Sun Oh established the first Department of Dermatology and Urology in Korea in 1917. Following the footsteps of...
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Allergic disease-related articles in Korean newspapers (1920–1972 year)

Kim KE

PURPOSE: This study aimed to investigate which Korean newspaper articles were reported on allergic diseases before the establishment of the Korean Academy of Asthma, Allergy and Clinical Immunology (KAAACI). METHODS: This...
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Performance Evaluation of Elecsys Vitamin D Total II Assay Using Roche Modular Analytics E170

Cho EJ, Kim H, Park J, Kim D, Cha Y, Lee HK

We evaluated the performance of a recently developed immunoassay, Elecsys vitamin D total II assay (Roche Diagnostics GmbH, Germany). Precision, linearity, and comparison studies were performed according to the Clinical...
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Management of chronic hepatitis B patients in immunetolerant phase: what latest guidelines recommend

Wong GL

The natural history of chronic hepatitis B (CHB) is complex and may run through different immune phases that may overlap. In particulars, the immune-tolerant phase is the most interesting and...
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Fundamental role of dendritic cells in inducing Th2 responses

Kim B, Kim TH

A mysterious puzzle in immunology is how the immune system decides what types of immune response to initiate against various stimuli. Although much is known about control of T helper...
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Current Management of Moderate-to-Severe Atopic Dermatitis: A Survey of Allergists, Pediatric Allergists and Dermatologists in Korea

Yum HY, Kim HH, Kim HJ, Kim WK, Lee SY, Li K, Lee DH, The KAAACI Work Group on Severe/Recalcitrant Atopic Dermatitis

PURPOSE: There is an unmet need for the treatment of moderate-to-severe atopic dermatitis (AD), leading to variation in management strategies. To investigate distinct features and treatment modalities according to physicians'...
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Perceptions of Severe Asthma and Asthma-COPD Overlap Syndrome Among Specialists: A Questionnaire Survey

Kim SH, Moon JY, Lee JH, Ban GY, Kim S, Kim MA, Kim JH, Kim MH, Park CS, Park SY, Kwon HS, Kwon JW, Jung JW, Kang HR, Park JS, Kim TB, Park HW, Cho YS, Yoo KH, Oh YM, Lee BJ, Jang AS, Cho SH, Park HS, Park CS, Yoon HJ, on behalf of the Severe Asthma Work Group, the Korean Academy of Asthma, Allergy and Clinical Immunology

PURPOSE: Severe asthma and asthma-chronic obstructive pulmonary disease (COPD) overlap syndrome (ACOS) are difficult to control and are often associated with poor clinical outcomes. However, much is not understood regarding...
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Wolves Trapped in the NETs–The Pathogenesis of Lupus Nephritis

Kim Y, Shim SC

Systemic lupus erythematous (SLE) is a systemic autoimmune disease with multi-organ inflammation caused by the production of pathogenic autoantibodies and immune complexes reflecting a global loss of tolerance. Lupus nephritis...
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Comparison between Newly Developed and Commercial Inhalant Skin Prick Test Reagents Using In Vivo and In Vitro Methods

Lee SC, Sim DW, Lee J, Jeong KY, Park KH, Lee JH, Kim JD, Park JW

BACKGROUND: We developed skin prick test (SPT) reagents for common inhalant allergens that reflected the real exposure in Korea. The study aim was to evaluate diagnostic usefulness and allergen potency...
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A whole new world: Asia Pacific Allergy online-only

Chang YS

No abstract available.
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