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A Radiation Induced Low-Grade Myofibroblastic Sarcoma in the Retropectoral Area After Breast Conserving Surgery: A Case Report

Park SY, Kim HJ, Lee J, Jeong JY, Byun J, Kim WH, Park B, Hong J

Low-grade myofibroblastic sarcoma (LGMFS) is a rare type of sarcoma, and its manifestation as a radiotherapy (RT)-induced sarcoma following RT for breast cancer is even more unusual. To date, only one...
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Value of Breast MRI and Nomogram After Negative Axillary Ultrasound for Predicting Axillary Lymph Node Metastasis in Patients With Clinically T1-2 N0 Breast Cancer

Song SE, Cho KR, Cho Y, Jung SP, Park KH, Woo OH, Seo BK

Background There are increasing concerns about that sentinel lymph node biopsy (SLNB) could be omitted in patients with clinically T1-2 N0 breast cancers who has negative axillary ultrasound (AUS). This study...
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Comparison of Quality of Life and Cosmetic Outcome of Latissimus Dorsi Mini-Flap With Breast Conservation Surgery Without Reconstruction

Kim Ji, Cheun JH, Jung JG, Kim Y, Lim C, Han Y, Jeon S, Hong Ky, Lee HB, Han W

Purpose: Latissimus dorsi mini-flap (LDMF) reconstruction after breast-conserving surgery (BCS) is a useful volume replacement technique when a large tumor is located in the upper or outer portion of the...
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Concomitant PIK3CA and TP53 Mutations in Breast Cancer: An Analysis of Clinicopathologic and Mutational Features, Neoadjuvant Therapeutic Response, and Prognosis

Lin XY, Guo L, Lin X, Wang Y, Zhang G

Purpose: PIK3CA and TP53 are the most prevalently mutated genes in breast cancer (BC). Previous studies have indicated an association between concomitant PIK3CA/TP53 mutations and shorter disease-free survival. As its clinical...
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Importance of Whole-Body Scintigraphy or Positron Emission Tomography for Early Detection of Femoral Lesions in Breast Cancer Patients Treated with Bisphosphonates

Cha SM, Kim YK, Shin HD, Park JY, Lee SH

Background: We hypothesized that most of the atypical femoral fractures (AFFs) associated with bisphosphonate treatment for breast cancer (BC) could be found before the fracture event in another radiological examination...
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Waiting Time for Breast Cancer Treatment in Korea: A Nationwide Cohort Study

Lee Yj, Jeong JH, Jung J, Yoo TK, Lee SB, Kim J, Ko BS, Kim HJ, Lee JW, Son BH, Chung IY

Purpose: This study aimed to analyze the waiting time for initial treatment after breast cancer diagnosis and determine the factors influencing treatment delay in South Korea. Methods: This nationwide retrospective cohort...
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Investigation of Factors Affecting Adherence to Adjuvant Hormone Therapy in Early-Stage Breast Cancer Patients: A Comprehensive Systematic Review

Yang S, Park SW, Bae SJ, Ahn SG, Jeong J, Park K

Purpose: Adherence and persistence to adjuvant hormone therapy (AHT) are seldom maintained among early-stage hormone receptor-positive breast cancer (BC) survivors, despite the significant clinical benefits of long-term AHT. As the...
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Development and External Validation of a Machine Learning Model to Predict Pathological Complete Response After Neoadjuvant Chemotherapy in Breast Cancer

Jung JJ, Kim EK, Kang E, Kim JH, Kim SH, Suh KJ, Kim SM, Jang M, Yun BL, Park SY, Lim C, Han W, Shin HC

Purpose: Several predictive models have been developed to predict the pathological complete response (pCR) after neoadjuvant chemotherapy (NAC); however, few are broadly applicable owing to radiologic complexity and institution-specific clinical...
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Metastatic choroidal melanoma in the breast: a case report and review of the literature

Abudalu L, Malhotra V, Nasir N, Titi S

The breast is an unusual site for metastases, accounting for less than 2% of malignant breast lesions but include those from malignant melanomas, carcinomas, sarcomas, and lymphomas from various organs....
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Can chemotherapy be omitted for patients with N0 or N1 endocrine-sensitive breast cancer treated with gonadotropin-releasing hormone agonist and tamoxifen?

Lee J, Park CS, Oh JH, Park IC, Seong MK, Noh WC, Kim HA

Purpose: Whether administering chemotherapy followed by tamoxifen plus a gonadotropin-releasing hormone (GnRH) agonist to treat patients with lower-risk hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer...
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Prognostic influences of B-cell lymphoma 2–positive expression on late recurrence in breast cancer

Kim HJ, Eom YH, Choi SH

Purpose: B-cell lymphoma 2 (BCL2) has an antiapoptotic role, however, has resulted in it being a powerful favorable prognostic factor in breast cancer. Several studies revealed BCL2 is strongly associated...
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Trends of axillary surgery in breast cancer patients with axillary lymph node metastasis: a comprehensive single-center retrospective study

Kim YJ, Kim HJ, Chung SY, Lee SK, Chae BJ, Yu J, Lee JE, Kim SW, Nam SJ, Ryu JM

Purpose: Based on the results of previous trials, de-escalation of axillary surgery after neoadjuvant chemotherapy (NAC) has increased in patients with axillary lymph node (ALN) metastasis at presentation. This study...
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Survival analysis of breast cancer patients after diagnosis of second primary malignancies, focusing on the second primary hematologic malignancy

Kim HJ, Lee J, Park IC, Han Y, Seong MK, Noh WC, Kang HJ, Kim HA, Park CS

Purpose: Although the overall survival (OS) of breast cancer patients is increasing with improved detection and therapies, so is the risk of breast cancer patients developing subsequent malignancies. We investigated...
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Frozen Sections in Decision-Making Regarding the Axillary Procedures in Breast Conserving Surgery for Intraductal Carcinoma at Preoperative Diagnosis

Kim S, Lee K, Alshahrani MA, Ahn JH, Lee J, Park HS

Background: Axillary evaluation is unnecessary for pure ductal carcinoma in situ (DCIS); however, it is performed because of the risk of upstaging to invasive cancer. We assessed the role of intraoperative...
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Efficacy of Olaparib in Treatment-Refractory, Metastatic Breast Cancer with Uncommon Somatic BRCA Mutations Detected in Circulating Tumor DNA

Yoon JK, Ahn J, Kim S, Kim HP, Kang Jk, Bang D, Lim Y, Kim TY

Poly(ADP-ribose) polymerase inhibitors have been shown dramatic responses in patients with BRCAness. However, clinical studies have been limited to breast cancer patients with germline mutations. Here, we describe a patient...
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Eflapegrastim versus Pegfilgrastim for Chemotherapy-Induced Neutropenia in Korean and Asian Patients with Early Breast Cancer: Results from the Two Phase III ADVANCE and RECOVER Studies

Moon YW, Kim SK, Lee KS, Lee MH, Park YH, Park KH, Kim GM, Lim S, Lee SA, Choi JD, Baek E, Han H, Baek S, Im SA

Purpose We investigated the consistent efficacy and safety of eflapegrastim, a novel long-acting granulocyte-colony stimulating factor (G-CSF), in Koreans and Asians compared with the pooled population of two global phase...
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Is bone mineral density a prognostic factor in postmenopausal women with luminal A breast cancer?

Lee S, Kim HY, Jung YJ, Kang SK, Kim JY, Yun MS

Purpose: Several studies are concerned about the association between bone mineral density (BMD) and the risk of breast cancer in postmenopausal women, but it is controversial. Therefore, we evaluated whether...
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Polyhexamethylene Biguaninde-Betaine Dressing Combined with Silver Sulfadiazine for Biofilm Control in an Advanced Cancer Wound: A Case Report

Kim KW, Jeon JH, Park JH, Jeon HB

Biofilm in a wound base can cause chronic infection and a persistent immune response in the host, inhibiting wound healing. Antibiotics and antiseptics may not be effective because the protective...
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Giant Axillary Ectopic Breast in a Male Patient: A Case Report

Sung KP, Kim CH

Axillary masses have diverse origins and require systematic diagnosis and treatment. Among various diseases, ectopic breast tissue occurs when the regression of primitive mammary tissue fails in a location other...
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Breast Cancer Metastatic to Gluteus Maximus: A Case Report

Roh S, Xu L

Breast cancer rarely metastasizes to skeletal muscle. Moreover, skeletal muscle is a rare site of metastasis for any type of cancer. In this study, we report an unexpected finding of...
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