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STAT3 as a Potential Target for Tumor Suppressive Effects of 15-Deoxy-Δ12,14-prostaglandin J2 in Triple Negative Breast Cancer

Kim SJ, Cho NC, Hahn YI, Kim SH, Fang X, Surh YJ

STAT3 plays a prominent role in proliferation and survival of tumor cells. Thus, STAT3 has been considered to be a prime target for development of anti-cancer therapeutics. The electrophilic cyclopentenone...
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Objective photographic assessments and comparisons of immediate bilateral breast reconstruction using deep inferior epigastric perforator flaps and implants

Han HH, Choi JM, Eom JS

Background The increasing number of bilateral breast cancer patients has been accompanied by a growing need for bilateral mastectomy with immediate reconstruction. However, little research has investigated the complications and...
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Comparison of clinicopathological characteristics and prognosis in breast cancer patients with different Breast Imaging Reporting and Data System categories

Kim BK, Ryu JM, Oh SJ, Han J, Choi JE, Jeong J, Suh YJ, Lee J, Sun WY, Korean Breast Cancer Society

Purpose: The Breast Imaging Reporting and Data System (BI-RADS) is a systematic and standardized scheme of the radiological findings of breast. However, there were different BI-RADS categories between breast cancers...
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Comparison of the Imaging Features of Lobular Carcinoma In Situ and Invasive Lobular Carcinoma of the Breast

Yoon GY, Cha JH, Kim HH, Bang MS, Lee HJ, Gong G

Purpose To investigate the usefulness of imaging features for differentiating between small lobular carcinoma in situ (LCIS) and invasive lobular carcinoma (ILC). Materials and Methods It included 52 female with LCISs...
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Intraductal Migration of a Breast Tissue Marker Placed under Ultrasound Guidance during COVIDInduced Delay of Surgery

Andrade G, Pereira A, Gonçalves L, Videira C

Breast tissue markers are common in current clinical practice and are susceptible to migration. Herein, we present the case of a 47-year-old woman with invasive breast carcinoma diagnosed through ultrasound-guided...
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Validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in Korean breast cancer patients

Kim J, Jo MW, Lee HJ, Ahn SH, Son BH, Lee JW, Lee SB

Objectives: This study evaluated the validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in postoperative breast cancer patients in South Korea. Methods: The study included...
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AC092127.1-miR-451a-AE binding protein 2 Signaling Facilitates Malignant Properties of Breast Cancer

Zhang X, Cong L, Xu D, Leng Q, Shi M, Zhou Y

Purpose: The purpose of the current study was to explore the functions and potential mechanism of miR-451a in breast cancer (BC). Methods: Quantitative reverse transcription real-time polymerase chain reaction was used...
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Unmet needs and quality of life of caregivers of Korean breast cancer survivors: a cross-sectional study

Lee JW, Lee J, Lee MH, Lee SK, Kim WS, Jung SY, Kim Z, Lee J, Youn HJ, the Study of Multi-disciplinARy Teamwork of breast cancer survivorSHIP (SMARTSHIP)

Purpose: As the survival rates of cancer patients have been increasing due to early diagnosis and technological advances in treatment, their caregiver burden has also emerged as an important issue....
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Magnetic Resonance Imaging-Guided Breast Biopsy in Korea: A 10-Year Follow-Up Experience

Cha SY, Ko EY, Han BK, Ko ES, Choi JS, Park KW, Lee JE

Purpose: To evaluate the accuracy of magnetic resonance imaging (MRI)-guided breast biopsy. Methods: We retrospectively reviewed the clinical data of 111 consecutive patients referred for MRI-guided breast biopsy after mammography and...
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Pyoderma Gangrenosum Mimicking Wound Infection after Breast Cancer Surgery

Kim D, Hur SM, Lee JS, Chin S, Lim CW, Kim Z

Postoperative pyoderma gangrenosum (PPG) is rare, and its diagnosis is often delayed because of its wound infection-mimicking course. A 53-year-old breast cancer patient who underwent breast-conserving surgery of the right...
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Automatic Pectoral Muscle Removal and Microcalcification Localization in Digital Mammograms

Gómez KAH, Echeverry-Correa JD, Gutiérrez

Objectives: Breast cancer is the most common cancer diagnosed in women, and microcalcification (MCC) clusters act as an early indicator. Thus, the detection of MCCs plays an important role in...
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Potential of AKT2 expression as a predictor of lymph-node metastasis in invasive breast carcinoma of no special type

Rustamadji P, Wiyarta E, Bethania KA, Kusmardi K

Background: Invasive breast carcinoma of no special type (IBC-NST) is the most common type of breast cancer and mainly causes regional lymph-node metastasis (LNM). We investigated the potential for AKT2...
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Implications of Tamoxifen Resistance in Palbociclib Efficacy for Patients with Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer: Subgroup Analyses of KCSG-BR15-10 (YoungPEARL)

Lee J, Im SA, Kim GM, Jung KH, Kang SY, Park IH, Kim JH, Ahn HK, Park YH

Purpose YoungPEARL (KCSG-BR15-10) trial demonstrated a significant progression-free survival (PFS) benefit for premenopausal patients with hormone receptor–positive/human epidermal growth factor receptor 2–negative (HR+/HER2–) metastatic breast cancer (MBC) for palbociclib plus...
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Synergistic Tumoricidal Effects of Alpha-Lipoic Acid and Radiotherapy on Human Breast Cancer Cells via HMGB1

Choi HS, Kim JH, Jang SJ, Yun JW, Kang KM, Jeong H, Ha IB, Jeong BK

Purpose Radiotherapy (RT) is one of main strategies of cancer treatment. However, some cancer cells are resistant to radiation-induced cell death, including apoptosis. Therefore, alternative approaches targeting different anti-tumor mechanisms...
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Male Breast Cancer: A Comparative Analysis from the National Cancer Database

Elimimian EB, Elson L, Li H, Liang H, Bilani N, Zabor EC, Statler A, Nahleh Z

Purpose: Breast cancer (BC) in males accounts for
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Efficacy of sentinel lymph node biopsy with radioisotope alone and the prediction of sentinel node status using PET-CT in breast cancer

Song R, Kwon SU, Yoon DS, Bae IE, Choi IS, Choi WJ, Lee SE, Moon JI, Sung NS, Lee SJ, Roh SJ, Kim SG

Purpose: Sentinel lymph node biopsy (SLNB) using both a radioactive isotope (RI) and blue dye is considered highly effective; however, there were limitations with the use of both agents in...
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Analysis of H3K4me3-ChIP-Seq and RNA-Seq data to understand the putative role of miRNAs and their target genes in breast cancer cell lines

Kotipalli A, Banerjee R, Kasibhatla SM, Joshi R

Breast cancer is one of the leading causes of cancer in women all over the world and accounts for ~25% of newly observed cancers in women. Epigenetic modifications influence differential...
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Mechanistic Targets of Diallyl Trisulfide in Human Breast Cancer Cells Identified by RNA-seq Analysis

Hahm ER, Kim SH, Mathan SV, Singh RP, Singh SV

Diallyl trisulfide (DATS), a metabolic by-product of processed garlic, is highly effective in inhibiting growth of human breast cancer cells in vitro and in vivo, but the underlying mechanisms are...
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Pain-related Prescribing Patterns and Associated Factor in Breast Cancer Patients

Lee J, Park IB, Seo HJ

Background: With an increase in the number of breast cancer survivors, greater importance is attached to health-related quality of life, particularly pain and symptom control. This study aimed to identify...
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Optimized Criteria for Sentinel Lymph Node Biopsy in Patients with Clinically Node Negative Breast Cancer

Kim JS, Lee MH, Kang SH, Cho J

Purpose: Sentinel lymph node biopsy (SLNB) is a well-established staging procedure for patients with early breast cancer who have clinically negative axillary lymph node. However, no consensus exists about the...
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