J Korean Ophthalmol Soc.  2007 Aug;48(8):1088-1095.

Central Corneal Thickness and Visual Field Progression in Primary Open-Angle Glaucoma

• Kim JH
• Lee EK
• Kim CS
• Lee NH

Abstract

PURPOSE: To find difference in the rate of visual field defect progression among primary open angle glaucoma (POAG) patients grouped according to central corneal thickness (CCT).
METHODS
The medical records of 87 eyes of 87 POAG patients who received were on regular treatment and had a minimum of 5 years of longitudinal Humphrey automated visual field follow-up were reviewed retrospectively. The patients were divided into 4 quartile groups by CCT, and the correlations among clinical factors, such as intraocular pressure (IOP), and change in mean deviation (MD), were analyzed.
RESULTS
The thinner cornea group showed a significant trend foward higher average, maximal, and yearly maximal IOP when the IOP was corrected by CCT (p<0.01), The rate of change in MD is significantly different; -0.33+/-0.6dB, -0.28+/-0.4dB, -0.09+/-0.2dB ,-0.02+/-0.2dB starting with the thinnest cornea group (p=0.036). Correlation analysis revealed a significant correlation between CCT and the rate of change in MD (r=0.351, p=0.001).
CONCLUSIONS
In POAG patients who were on regular treatment at a tertiary referral hospital, patients with thinner cornea showed faster visual field defect progression.

Keyword

Cyclodialysis cleft; Intraocular pressure; Refractive power; Trauma

MeSH Terms

Cornea
Follow-Up Studies
Glaucoma, Open-Angle*
Humans
Intraocular Pressure
Medical Records
Retrospective Studies
Tertiary Care Centers
Visual Fields*

Figure

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  Figure 1. Scattergram of changes in mean deviation in automated visual field test and corrected intraocular pressure with central corneal thickness (Pearson correlation test, r=-0.302, p=0.004).

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  Figure 2. Scattergram of central corneal thickness and change in mean deviation in automated visual field test (Pearson correlation test, r=0.351, p=0.001).

Reference

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