J Korean Ophthalmol Soc.  1986 Dec;27(6):1059-1063.

The Corneal Endothelial Cell in Glaucoma and Ocular Hypertension

• Kee CW
• Youn DH

Abstract

In order to assess a possible damage to the corneal endothelium by the increased intraocular pressure, we investigated the 8 eyes of angle closure glaucoma, 10 eyes of ocular hypertension, 20 eyes of primary open angle glaucoma, and 15 normal eyes as a control group. We photographed the central corneal endothelium with a non contact specular microscope and measured the central corneal thickness three times with a Haag-Streit pachymeter. As compared to the normal eyes the glaucomatous eyes and ocular hypertensive eyes showed a statistically significant decrease of central corneal endothelial cell density(p<0.005), but in central corneal thickness there was no statistically significant difference between two. There was a reverse correlation between the intraocular pressure and the central corneal endothelial cell density(p<0.05), but no correlations were seen between the intraocular pressure and the central corneal thickness and between the central corneal endothelial cell density and the central corneal thickness(p>0.1).

MeSH Terms

Endothelial Cells*
Endothelium, Corneal
Glaucoma*
Glaucoma, Angle-Closure
Glaucoma, Open-Angle
Intraocular Pressure
Ocular Hypertension*