Tuberc Respir Dis.  2014 Jul;77(1):34-37.

Multiple Hypercoagulability Disorders at Presentation of Non-Small-Cell Lung Cancer

Affiliations
  • 1Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea. jsryu@inha.ac.kr

Abstract

Hypercoagulability disorders are commonly encountered in clinical situations in patients with a variety of cancers. However, several hypercoagulability disorders presenting as first symptoms or signs in cancer patients have rarely been reported. We herein described a case of a woman with adenocarcinoma of the lung presenting with deep vein thrombosis, nonbacterial thrombotic endocarditis, recurrent cerebral embolic infarction, and heart failure.

Keyword

Venous Thrombosis; Heart Failure; Thrombophilia; Endocarditis, Non-Infective; Carcinoma, Non-Small-Cell Lung

MeSH Terms

Adenocarcinoma
Carcinoma, Non-Small-Cell Lung
Endocarditis
Endocarditis, Non-Infective
Female
Heart Failure
Humans
Infarction
Lung
Lung Neoplasms*
Thrombophilia*
Venous Thrombosis

Figure

  • Figure 1 A 2×1.2-cm-sized nodular lesion in the left lingular division abutting to mediastinal pleura (A, arrow) and lymphadenopathies on the left paraaortic area, on chest CT scan at the time of diagnosis (B, arrow).

  • Figure 2 Computed tomogram angiogram for the legs showing venous thrombosis at the popliteal vein (A, arrow) and calf vein (B, arrow) of the right leg.

  • Figure 3 Brain magnetic resonance image showing a subacute stage infarction involving a territory of the right middle cerebral artery.

  • Figure 4 Vegetation measuring 9 mm in size on the posterior mitral leaflet shown on transthoracic echocardiogram (A, arrow), and diffuse stenosis of the posterolateral branch of the right coronary artery shown on coronary angiogram (B, arrow).


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