Urogenit Tract Infect.  2015 Oct;10(2):112-119. 10.14777/uti.2015.10.2.112.

Change of Antibiotic Resistance to the Causative Organisms of Pelvic Wound Infection for Recent 5 Years

• Kim YS
• Kim SK
• Cho IC
• Ko JS
• Lee GI
• Min SK

• KMID: 2319436
• DOI: http://doi.org/10.14777/uti.2015.10.2.112

Abstract

PURPOSE
We researched microbial profiles and the antimicrobial resistance profile of wound infection of the pelvic area in Korea for the recent 5 years in order to provide useful information on the choice of adequate drugs in the treatment of pelvic wound infection.
MATERIALS AND METHODS
We retrospectively analyzed 211 pelvic wound culture samples and their antimicrobial resistance in 198 in- or out-patients of the Urology and Plastic surgery department from January 2010 to December 2014.
RESULTS
Of the total samples, Staphylococcus aureus was isolated most frequently (35.3%), followed by Escherichia coli (15.1%), Staphylococcus epidermidis (12.6%), Staphylococcus haemolyticus (12.6%), Staphylococcus lugdunensis (8.4%), Pseudomonas aeruginosa (6.7%), Enterococcus spp. (4.2%), and Streptococcus spp. (3.3%). There were no notable changes of bacterial distribution for 5 years. For Gram-positive isolates, the oxacillin resistance rate for Gram-positive bacteria was 42.6% and showed an increasing tendency for the recent 5 years. Piperacillin, rifampicin, and vancomycin had low resistance for Gram-positive bacteria. Carbapenems, piperacillin/tazobactam had low resistance for Gram-negative bacteria. The Gram-positive organisms were more sensitive to many antibiotics in contrast to the Gram-negative organisms.
CONCLUSIONS
Of varied causative organisms and susceptibility of the pelvic wound site, the most frequently infected organisms of the pelvic area were S. aureus, followed by E. coli. The methicillin resistive S. aureus (MRSA) incidence showed a tendency to increase yearly, thus selection or early change of antibiotics considering MRSA is recommended if the antibiotic response is poor. Gram-negative bacteria has a higher resistance rate compared with Gram-positive bacteria and had carbapenems and piperacillin/tazobactam.

Keyword

Pelvic infection; Wound infection; Drug resistance; Methicillin

MeSH Terms

Anti-Bacterial Agents
Carbapenems
Drug Resistance
Drug Resistance, Microbial*
Enterococcus
Escherichia coli
Gram-Negative Bacteria
Gram-Positive Bacteria
Humans
Incidence
Korea
Methicillin
Methicillin-Resistant Staphylococcus aureus
Outpatients
Oxacillin
Pelvic Infection
Piperacillin
Pseudomonas aeruginosa
Retrospective Studies
Rifampin
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
Staphylococcus lugdunensis
Streptococcus
Surgery, Plastic
Urology
Vancomycin
Wound Infection*
Wounds and Injuries*
Anti-Bacterial Agents
Carbapenems
Methicillin
Oxacillin
Piperacillin
Rifampin
Vancomycin

Figure

• 

  Fig. 1. Incidence of causative organisms of pelvic wound infection for 5 years.

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