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Comparison of In Vivo Pharmacokinetics and Pharmacodynamics of Vancomycin Products Available in Korea

Kim HK, Choi SM, Kang G, Park KH, Lee DG, Park WB, Rhee SJ, Lee S, Jung SI, Jang HC

PURPOSE: Few studies have been investigated the in vivo efficacy of generic vancomycin products available outside of the United States. In this study, we aimed to compare the in vivo...
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Identification of Molecular Signatures in Mild Intrinsic Atopic Dermatitis by Bioinformatics Analysis

Yin H, Wang S, Gu C

BACKGROUND: Atopic dermatitis (AD) is recognized as a common inflammatory skin disease and frequently occurred in Asian and Black individuals. OBJECTIVE: Since the limitation of dataset associated with human severe AD,...
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Season and Temperature Effects on Bloodstream Infection Incidence in a Korean Tertiary Referral Hospital

Sohn YS, Byun JH, Kim YA, Shin DC, Lee K

BACKGROUND: The weather has well-documented effects on infectious disease and reports suggest that summer peaks in the incidences of gram-negative bacterial infections among hospitalized patients. We evaluated how season and...
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Culture-Positive Spontaneous Ascitic Infection in Patients with Acute Decompensated Cirrhosis: Multidrug-Resistant Pathogens and Antibiotic Strategies

Liu J, Gao Y, Wang X, Qian Z, Chen J, Huang Y, Meng Z, Lu X, Deng G, Liu F, Zhang Z, Li H, Zheng X

PURPOSE: This study investigated multidrug-resistant (MDR) pathogens and antibiotic strategies of culture-positive spontaneous ascitic infection (SAI) in patients with acute decompensated cirrhosis. MATERIALS AND METHODS: We retrospectively analyzed 432 acute decompensated...
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Livestock-associated methicillin-resistant Staphylococcus aureus in Korea: antimicrobial resistance and molecular characteristics of LA-MRSA strains isolated from pigs, pig farmers, and farm environment

Back SH, Eom HS, Lee HH, Lee GY, Park KT, Yang SJ

The emergence of livestock-associated (LA)-methicillin-resistant Staphylococcus aureus (MRSA) in livestock animal has become a significant zoonotic concern. In the present study, we investigated nationwide prevalence of LA-MRSA across pork production...
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The Use of Inappropriate Antibiotics in Patients Admitted to Intensive Care Units with Nursing Home–Acquired Pneumonia at a Korean Teaching Hospital

Kim DH, Kim HJ, Koo HW, Bae W, Park SH, Koo HK, Park HK, Lee SS, Kang HK

BACKGROUND: Use of appropriate antibiotics for the treatment of pneumonia is integral in patients admitted to intensive care units (ICUs). Although it is recommended that empirical treatment regimens should be...
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Linezolid Resistance in Methicillin-Resistant Staphylococcus aureus in Korea: High Rate of False Resistance to Linezolid by the VITEK 2 System

Yoo IY, Kang OK, Shim HJ, Huh HJ, Lee NY

As various linezolid resistance mechanisms have been identified in methicillin-resistant Staphylococcus aureus (MRSA), we investigated the molecular characteristics of MRSA with elevated linezolid minimum inhibitory concentrations (MICs), using the VITEK...
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Clinical Review of Staphylococcal Scalded Skin Syndrome in a Single Institution for 18 Years, 2001–2018

Lee SJ, Lee DW

Staphylococcal scalded skin syndrome (SSSS) is a disease caused by exfoliative toxin. The purpose of this study is to analyze clinical features, laboratory findings and treatment outcome of patients who...
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Clinical Review of Staphylococcal Scalded Skin Syndrome in a Single Institution for 18 Years, 2001–2018

Lee SJ, Lee DW

Staphylococcal scalded skin syndrome (SSSS) is a disease caused by exfoliative toxin. The purpose of this study is to analyze clinical features, laboratory findings and treatment outcome of patients who...
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Clinical Review of Staphylococcal Scalded Skin Syndrome in a Single Institution for 18 Years, 2001–2018

Lee SJ, Lee DW

Staphylococcal scalded skin syndrome (SSSS) is a disease caused by exfoliative toxin. The purpose of this study is to analyze clinical features, laboratory findings and treatment outcome of patients who...
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The Activation of PPAR-α and Wnt/β-catenin by Luffa cylindrica Supercritical Carbon Dioxide Extract

Kim B

Luffa cylindrica (LC) is a very fast-growing climber and its fruit have been considered as agricultural wastes. We conducted to check the comparative qualities of ethanol solvent extraction (LCE) and...
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The Characteristics of Staphylococcal Scalded Skin Syndrome in Atopic Dermatitis

Jung WJ, Kim SW, Hwang YH

OBJECTIVES: Staphylococcal scalded skin syndrome (4S), a blistering dermatosis caused by exfoliative toxins from Staphylococcus aureus, occurs frequently in patients with atopic dermatitis (AD). However, association between 4S and AD...
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Antibiotic sensitivity and resistance of bacteria from odontogenic maxillofacial abscesses

Kang SH, Kim MK

OBJECTIVES: This study investigated the types and antibiotic sensitivity of bacteria in odontogenic abscesses. MATERIALS AND METHODS: Pus specimens from 1,772 patients were collected from affected areas during incision and drainage,...
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The Cefazolin Inoculum Effect and the Presence of type A blaZ Gene according to agr Genotype in Methicillin-Susceptible Staphylococcus aureus Bacteremia

Lee SO, Lee S, Park S, Lee JE, Lee SH

BACKGROUND: Recent data suggests the inoculum effect of methicillin-susceptible Staphylococcus aureus (MSSA) against beta-lactam antibiotics and their association with functionality or genotypic variation of agr locus. METHODS: MSSA blood isolates were...
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Molecular Epidemiologic Study of a Methicillin-resistant Staphylococcus aureus Outbreak at a Newborn Nursery and Neonatal Intensive Care Unit

Kang HM, Park KC, Lee KY, Park J, Park SH, Lee DG, Kim JH

PURPOSE: This study aimed to investigate the molecular epidemiology of a methicillin-resistant Staphylococcus aureus (MRSA) outbreak at a newborn nursery and neonatal intensive care unit (NICU). METHODS: During the outbreak, from...
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Changing Susceptibility of Staphylococcus aureus in Children with Skin and Soft Tissue Infections: a Single Center Experience from 2010 to 2018

Cho YS, Lee SH, Lee TJ

PURPOSE: Staphylococcus aureus is a major cause of skin and soft tissue infections (SSTIs). This study aimed to determine the temporal trends in antibiotic susceptibility of S. aureus in SSTI...
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Antimicrobial Resistance in Bacterial Isolates Recovered from Nursing Hospitals between 2014 and 2017

Yun SH, Gwon B, Hong HL, Lim HS, Lee KR, Jang I, Yoon EJ, Jeong SH

BACKGROUND: Antimicrobial resistance (AMR) is an issue not only with regard to public health, but also in terms of economic impact. AMR surveillance has mainly been carried out in general...
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Ocular Manifestations, Treatment Outcome and Clinical Course of Infective Keratitis of Keratitis-Ichthyosis-Deafness Syndrome

Son KY, Paik DW, Cho EH, Shin D, Woo HI, Chung TY, Lim DH

PURPOSE: To report the ocular manifestations and treatment outcomes of infective keratitis in a patient with keratitis-ichthyosis-deafness (KID) syndrome and to report a newly discovered mutation in the GJB2 gene...
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Molecular Epidemiology of Staphylococcus aureus in Skin and Soft Tissue Infections and Bone and Joint Infections in Korean Children

Park SG, Lee HS, Park JY, Lee H

BACKGROUND: Community acquired-methicillin resistant Staphylococcus aureus (MRSA) clones, including ST1, ST8, and ST30 are reported worldwide. However, data among Korean children are limited. Thus, we investigated the molecular characteristics of...
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Awareness and Competency of Multi-Drug Resistant Organisms Infection Control in Nursing Students with Clinical Practice

Ryu D, Ryu E

PURPOSE: The aim of this study was to identify awareness and competency for Multi-Drug Resistant Organisms (MDRO) infection control in nursing students with experience of clinical practice. METHODS: This cross-sectional descriptive...
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