- Potassium-competitive Acid Blockers: A New Therapeutic Strategy for Helicobacter pylori Eradication
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Ahn BY, Cho SJ
- KMID: 2545620
- Korean J Helicobacter Up Gastrointest Res.
- 2023 Sep;23(3):174-179.
- doi: 10.7704/kjhugr.2023.0041
The escalating prevalence of clarithromycin resistance in cases of Helicobacter pylori, insufficient acid suppression, and pharmacodynamic variations secondary to inter-individual differences in CYP2C19 polymorphism collectively contribute to suboptimal eradication rates... -
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- Optimizing Helicobacter pylori Treatment: An Updated Review of Empirical and Susceptibility Test-Based Treatments
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Ishibashi F, Suzuki S, Nagai M, Mochida K, Morishita T
- KMID: 2546011
- Gut Liver.
- 2023 Sep;17(5):684-697.
- doi: 10.5009/gnl220429
As the rate of discovery of drug-resistant Helicobacter pylori cases increases worldwide, the relevant societies have updated their guidelines for primary eradication regimens. A promising strategy against drug-resistant H. pylori... -
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- Microbial isolates and antibiotic sensitivity in patients hospitalized with odontogenic infections at a tertiary center over 10 years
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Kwon GB, Kim CH
- KMID: 2545585
- J Korean Assoc Oral Maxillofac Surg.
- 2023 Aug;49(4):198-207.
- doi: 10.5125/jkaoms.2023.49.4.198
Objectives: This study investigated causative strains and their antibiotic sensitivity in patients who were hospitalized for maxillofacial odontogenic infections at a tertiary center in South Korea over the past 10... -
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- Epidemiological characteristics of carbapenemaseproducing Enterobacteriaceae outbreaks in the Republic of Korea between 2017 and 2022
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Jeong H, Hyun J, Lee YK
- KMID: 2545873
- Osong Public Health Res Perspect.
- 2023 Aug;14(4):312-320.
- doi: 10.24171/j.phrp.2023.0069
Objectives: We aimed to describe the epidemiological characteristics of carbapenemaseproducing Enterobacteriaceae (CPE) outbreaks in healthcare settings in the Republic of Korea between 2017 and 2022. Methods: Under the national notifiable disease... -
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- Antibiotic Stewardship: A Key Strategy to Combat Antibiotic Resistance
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Park SY
- KMID: 2544842
- Korean J Med.
- 2023 Aug;98(4):151-154.
- doi: 10.3904/kjm.2023.98.4.151
Antibiotic stewardship is a vital strategy to address antibiotic resistance by promoting responsible antibiotic use. It is aimed at improving patient outcomes, reducing resistance, minimizing adverse effects, and lowering healthcare... -
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- Efficacy of 7-day Tailored Therapy for Helicobacter pylori Eradication based on Clarithromycin Resistance
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Bae JH, Jo HH, Kwon JG, Kim EY
- KMID: 2544934
- Korean J Gastroenterol.
- 2023 Jul;82(1):10-17.
- doi: 10.4166/kjg.2023.039
Background/Aims: Increasing resistance to clarithromycin (CAM) of Helicobacter pylori (H. pylori) is one of the main causes of recent decrease in eradication rate of standard triple therapy. The aim of... -
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- Cellular Dormancy in Cancer: Mechanisms and Potential Targeting Strategies
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Min HY, Lee HY
- KMID: 2544156
- Cancer Res Treat.
- 2023 Jul;55(3):720-736.
- doi: 10.4143/crt.2023.468
Cancer is a leading cause of disease-related mortality worldwide. Drug resistance is one of the primary reasons for the failure of anticancer therapy. There are a number of underlying mechanisms... -
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- Korean farm animal veterinarians’ perception and practice of prudent use of antimicrobials
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Choi Y, Joo S, Lee SW, Lee HJ, Chun MS
- KMID: 2543764
- Korean J Vet Res.
- 2023 Jun;63(2):e17.
- doi: 10.14405/kjvr.20230007
Antimicrobial (AM) resistance is a growing threat in human and veterinary medicine, spreading across species and perceived as One-Health issue. Prudent use of AM products is essential in mitigating this... -
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- The genomic landscape associated with resistance to aromatase inhibitors in breast cancer
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Sadasivam K, Manoharan JP, Palanisamy H, Vidyalakshmi S
- KMID: 2543699
- Genomics Inform.
- 2023 Jun;21(2):e20.
- doi: 10.5808/gi.23012
Aromatase inhibitors (AI) are drugs that are widely used in treating estrogen receptor (ER)–positive breast cancer patients. Drug resistance is a major obstacle to aromatase inhibition therapy. There are diverse... -
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- Difficult-to-treat Acinetobacter Bacteremia in Hospital Acquired Pneumonia Patients, South Korea, 2016-2019
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Kim S, Kim D, Lee EH, Song JE, Hyun J
- KMID: 2543145
- Korean J healthc assoc Infect Control Prev.
- 2023 Jun;28(1):143-154.
- doi: 10.14192/kjicp.2023.28.1.143
Background: Difficult-to-treat resistance (DTR) Acinetobacter infection has emerged as a worldwide concern and causes substantial morbidity and mortality. This study aimed to evaluate the patterns of antimicrobial resistance (AMR) and... -
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- Phenotypic Characteristics and Clonal Relationships of Stenotrophomonas maltophilia Isolates in Hospitalized Adults from a Private Center in Lima, Peru
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Ortiz-Gómez T, Toledano P, Gomez AC, López M, Alonso CA, Ruiz J, Lagos J, Sáenz Y
- KMID: 2544446
- Infect Chemother.
- 2023 Jun;55(2):278-282.
- doi: 10.3947/ic.2023.0003
Stenotrophomonas maltophilia is an opportunistic pathogen, often associated with nosocomial infections. Ten S. maltophilia were isolated from clinical samples during the period January 2021 and June 2022. Eight (80%) patients... -
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- Treatment of Multidrug-resistant Pseudomonas aeruginosa Bacteremia in a Immunocompromised Child With Ceftolozane-tazobactam
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Yu H, Shin A, Kim DR, Choi J, Ju HY, Cho J, Kang CI, Kim YJ
- KMID: 2544424
- Pediatr Infect Vaccine.
- 2023 Apr;30(1):47-54.
- doi: 10.14776/piv.2023.30.e5
With the widespread use of broad-spectrum antibiotics in clinical practice, the emergence of multidrug-resistant (MDR) gram-negative bacteria has become a global problem. The MDR Pseudomonas aeruginosa infection is especially difficult... -
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- Adverse effects of hydroxyurea used for the treatment of myeloproliferative neoplasms
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Kim SY
- KMID: 2541906
- J Korean Med Assoc.
- 2023 Apr;66(4):253-257.
- doi: 10.5124/jkma.2023.66.4.253
Background: Hydroxyurea is administered to control elevated blood counts in patients with myeloproliferative neoplasms (MPNs) to reduce the risk of thrombosis and mortality. We reviewed the side effects of hydroxyurea,... -
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- Next-generation sequencing analysis of hepatitis C virus resistance–associated substitutions in direct-acting antiviral failure in South Korea
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Kim KA, Lee S, Park HJ, Jang ES, Lee YJ, Cho SB, Kim YS, Kim IH, Lee BS, Chung WJ, Ahn SH, Kim S, Jeong SH
- KMID: 2541438
- Clin Mol Hepatol.
- 2023 Apr;29(2):496-509.
- doi: 10.3350/cmh.2022.0345
Background/Aims: We used next-generation sequencing (NGS) to analyze resistance-associated substitutions (RASs) and retreatment outcomes in patients with chronic hepatitis C virus (HCV) infection who failed direct-acting antiviral agent (DAA) treatment... -
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- Antibiotic resistance in Neisseria gonorrhoeae: broad-spectrum drug target identification using subtractive genomics
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Omeershffudin UNM, Kumar S
- KMID: 2543684
- Genomics Inform.
- 2023 Mar;21(1):e5.
- doi: 10.5808/gi.22066
Neisseria gonorrhoeae is a Gram-negative aerobic diplococcus bacterium that primarily causes sexually transmitted infections through direct human sexual contact. It is a major public health threat due to its impact... -
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- Antibiogram of Multidrug-Resistant Bacteria Based on Sepsis Onset Location in Korea: A Multicenter Cohort Study
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Kim HJ, Oh DK, Lim SY, Cho YJ, Park S, Suh GY, Lim CM, Lee YJ
- KMID: 2540433
- J Korean Med Sci.
- 2023 Mar;38(10):e75.
- doi: 10.3346/jkms.2023.38.e75
Background: Administration of adequate antibiotics is crucial for better outcomes in sepsis. Because no uniform tool can accurately assess the risk of multidrug-resistant (MDR) pathogens, a local antibiogram is necessary.... -
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- Developing Core Elements and Checklist Items for Implementing Antimicrobial Stewardship Programs in Korean General Hospitals: A Modified Delphi Survey
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Cheong HS, Park KH, Kim B, Eun BW, Kim Hs, Kim YC, Lee H, Jeong SJ, Moon C, Kim SW, Yoon YK, Hwang IS, Park CS, Lee MS, Kim HB, Shin JY, Kwon KT
- KMID: 2541532
- Infect Chemother.
- 2023 Mar;55(1):59-68.
- doi: 10.3947/ic.2022.0169
Background: Antimicrobial stewardship programs (ASPs) aim to optimize antimicrobial use by minimizing the spread of antimicrobial resistance. The core elements for implementing ASPs in healthcare facilities have been developed by... -
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- Quetiapine Treatment for Post-traumatic Stress Disorder: A Systematic Review of the Literature
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Crapanzano C, Damiani S, Casolaro I, Amendola C
- KMID: 2539649
- Clin Psychopharmacol Neurosci.
- 2023 Feb;21(1):49-56.
- doi: 10.9758/cpn.2023.21.1.49
Paroxetine and Sertraline are the only medications approved in posttraumatic stress disorder (PTSD). However, about 60% of traumatized patients fail to show an adequate clinical response. Second generation antipsychotics are... -
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- Core Elements for Implementing Antimicrobial Stewardship Programs in Korean General Hospitals
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Cheong HS, Park KH, Kim HB, Kim SW, Kim B, Moon C, Lee MS, Yoon YK, Jeong SJ, Kim YC, Eun BW, Lee H, Shin JY, Kim Hs, Hwang IS, Park CS, Kwon KT, Korean Society for Antimicrobial Therapy, The Korean Society of Infectious Diseases, Korean Society for Healthcare-associated Infection Control and Prevention, Korean Society of Pediatric Infectious Diseases, Korean Society of Health-System Pharmacists
- KMID: 2539136
- Korean J Med.
- 2023 Feb;98(1):11-39.
- doi: 10.3904/kjm.2023.98.1.11
Currently, antimicrobial resistance (AMR) is a major threat to global public health. To overcome this crisis, antimicrobial stewardship programs (ASPs) have been proposed. An ASP supports the optimal use of... -
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- Nationwide Treatment Outcomes of Patients With Multidrug/RifampinResistant Tuberculosis in Korea, 2011–2017: A Retrospective Cohort Study (Korean TB-POST)
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Choi H, Mok J, Kang YA, Jeong D, Kang HY, Kim HJ, Kim HS, Jeon D
- KMID: 2539197
- J Korean Med Sci.
- 2023 Feb;38(5):e33.
- doi: 10.3346/jkms.2023.38.e33
Background: The treatment outcomes of patients with multidrug/rifampin-resistant (MDR/RR) tuberculosis (TB) are important indicators that reflect the current status of TB management and identify the key challenges encountered by TB... -
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