Korean J Med.
2008 May;74(5):561-565.
A case of brucella endocarditis with spondylitis in a patient with multiple myeloma
- Affiliations
-
- 1Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea. medkid@dreamwiz.com
- 2Department of Laboratory Medicine, Chonnam National University Medical School, Gwangju, Korea.
- 3Department of Thoracic and Cardiovascular Surgery, Chonnam National University Medical School, Gwangju, Korea.
- 4Asian-Pacific Research Foundation For Infectious Disease(ARFID), Seoul, Korea.
Abstract
- Brucella endocarditis is a rare complication, but it is responsible for the majority of deaths related to this illness. A 67 year-old man presented with complaints of fever and lower back pain that he had experienced during the previous four weeks. The laboratory finding showed pancytopenia and an inverted total protein/globulin ratio. Multiple myeloma was diagnosed by bone marrow biopsy and serum electrophorosis. The spine MRI scan demonstrated spondylitis with epidural abscess (L5-S1). On the echocardiographic examination, there was vegetation on the right coronary cusp of the aortic valve and perivalvular abscess. The blood isolate was confirmed as Brucella abortus by using DNA sequencing of the 16S rRNA and the omp2a and omp2b genes. The clinical manifestations improved after appropriate antibiotics and aortic valve replacement. We describe here the first Korean case of human brucella endocarditis that was treated by valve replacement.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Streptococcus Spondylitis Concomitant Infectious Endocarditis: A Case Report
- Successful Medical Treatment of Prosthetic Mitral Valve Endocarditis Caused by Brucella abortus
- Brucella Endocarditis with Splenic Abscess: A Report of the First Case Diagnosed in Korea
- The Association between Multiple Myeloma and Ankylosing Spondylitis: A Report of Two Cases
- Back Pain Secondary to Brucella Spondylitis in the Lumbar Region
