Korean J Hepatobiliary Pancreat Surg.  2010 Dec;14(4):262-266.

A Case of Liver Metastasis of Gastrointestinal Stromal Tumor That Was Resected after Treatment with Imatinib Mesylate and Sunitinib

Affiliations
  • 1Department of Surgery, Wonkwang University Hospital, Wonkwang University College of Medicine, Korea. chaekm@wonkwang.ac.kr
  • 2Department of Hemato-Oncology, Wonkwang University Hospital, Wonkwang University College of Medicine, Korea.
  • 3Department of Radiology, Wonkwang University Hospital, Wonkwang University College of Medicine, Korea.
  • 4Department of Pathology, Wonkwang University Hospital, Wonkwang University College of Medicine, Korea.

Abstract

A 65-year old man underwent wedge resection for a gastrointestinal stromal tumor (GIST) of the gastric fundus in 1997. In 2003, the abdominal CT and sono-guided biopsy revealed he had a large GIST liver metastasis. He underwent treatment with 400 mg/day of imatinib mesylate. As a result, the liver metastasis markedly decreased in size. However, focal progression of the liver metastasis was observed on the follow up CT, so we increased the imatinib from 400 mg/day to 800 mg/day. We then performed extended left hepatectomy. We report here on a patient who presented with an isolated metastatic GIST to the liver, and the patient was successfully treated with imatinib therapy and hemihepatectomy.

Keyword

Gastrointestinal stromal tumors; Imatinib mesylate; Liver metastasis; Liver resection

MeSH Terms

Benzamides
Biopsy
Follow-Up Studies
Gastric Fundus
Gastrointestinal Stromal Tumors
Hepatectomy
Humans
Indoles
Liver
Mesylates
Neoplasm Metastasis
Piperazines
Pyrimidines
Pyrroles
Imatinib Mesylate
Benzamides
Indoles
Mesylates
Piperazines
Pyrimidines
Pyrroles
Full Text Links
  • KJHBPS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr