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Genetic Characterization of Molecular Targets in Korean Patients with Gastrointestinal Stromal Tumors

Park J, Yoo HM, Sul HJ, Shin S, Lee SW, Kim JG

PURPOSE: Gastrointestinal stromal tumors (GISTs) frequently harbor activating gene mutations in either KIT or platelet-derived growth factor receptor A (PDGFRA) and are highly responsive to several selective tyrosine kinase inhibitors....
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Dilation of the Duodenal Limb after Resection of a Huge Jejunal Gastrointestinal Stromal Tumor

Kim GH, Kim DH

No abstract available.
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Association between Recurrence and Survival Rates According to the Location of Gastric Gastrointestinal Stromal Tumor

Yu YJ, Kim TH, Oh JH, Chung WC

BACKGROUND/AIMS: This study aimed to evaluate the clinicopathological parameters of gastric gastrointestinal stromal tumors (GISTs) and to investigate the effect of tumor site on clinical outcomes. MATERIALS AND METHODS: Patients treated...
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Clinical Relevance of the Location of Gastric Gastrointestinal Stromal Tumors

Gong EJ

No abstract available.
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Factors Affecting the Length of Hospitalization after Laparoscopic Resection of Gastric Subepithelial Tumor

Chang YS

A subepithelial tumor (SET) is a common disease of the stomach. A gastrointestinal stromal tumor (GIST), which has malignant potential, is the most common tumor among SETs. The definite treatment...
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Contrast Enhanced Endoscopic Ultrasound Imaging for Gastrointestinal Subepithelial Tumors

Tamura T, Kitano M

Subepithelial tumors are divided into benign subepithelial and potentially malignant gastrointestinal stromal tumors. It is difficult to distinguish between these tumor types. Contrast-enhanced harmonic endoscopic ultrasound is reportedly useful for...
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Current Status of Endoscopic Ultrasonography in Gastrointestinal Subepithelial Tumors

Kim SG, Song JH, Hwang JH

Gastrointestinal subepithelial tumors (GSTs) are usually detected incidentally on endoscopic or radiologic examinations. In conventional endoscopy, a GST usually presents as a protuberant lesion with an intact mucosal surface. As...
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Endoscopic features of gastrointestinal stromal tumor in the small intestine

Ihara Y, Torisu T, Moriyama T, Umeno J, Hirano A, Okamoto Y, Hori Y, Yamamoto H, Kitazono T, Esaki M

BACKGROUND/AIMS: Gastrointestinal stromal tumor (GIST) is one of the most common types of submucosal tumors (SMTs). Because of GIST's malignant potential, it is crucial to differentiate it from other SMTs....
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Omental Patching and Purse-String Endosuture Closure after Endoscopic Full-Thickness Resection in Patients with Gastric Gastrointestinal Stromal Tumors

Inayat F, Aslam A, Grunwald M, Hussain Q, Hurairah A, Iqbal S

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract, primarily arising from the stomach. With the widespread utilization of and technical advancements in endoscopy, gastric...
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Imatinib-induced hepatitis treated by corticosteroids in a patient with metastatic gastrointestinal stromal tumor

Kang MK, Lee HJ, Choi JH

Imatinib mesylate is currently used as the first-line treatment for metastatic gastrointestinal stromal tumors (GISTs). Imatinib-induced hepatotoxicity in patients with GIST is very rare. Its features vary from subclinical elevation...
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Predicting Malignancy Risk in Gastrointestinal Subepithelial Tumors with Contrast-Enhanced Harmonic Endoscopic Ultrasonography Using Perfusion Analysis Software

Lee HS, Cho CM, Kwon YH, Nam SY

BACKGROUND/AIMS: Contrast-enhanced harmonic endoscopic ultrasonography (CEH-EUS) is a promising imaging modality that can differentiate subepithelial tumors (SETs) by detecting the degree of enhancement. However, whether CEH-EUS alone can predict the...
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Comparison of the Diagnostic Ability of Endoscopic Ultrasonography and Abdominopelvic Computed Tomography in the Diagnosis of Gastric Subepithelial Tumors

Kim SY, Shim KN, Lee JH, Lim JY, Kim TO, Choe AR, Tae CH, Jung HK, Moon CM, Kim SE, Jung SA

BACKGROUND/AIMS: Endoscopic ultrasonography (EUS) is the most efficient imaging modality for gastric subepithelial tumors (SETs). However, abdominopelvic computed tomography (APCT) has other advantages in evaluating the characteristics, local extension, or...
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Molecular and Clinicopathological Features of Gastrointestinal Stromal Tumors in Vietnamese Patients

Ngo QD, Pham QT, Phan DA, Hoang AV, Hua TN, Nguyen ST

BACKGROUND: Gastrointestinal stromal tumors (GISTs) are the most frequent mesenchymal neoplasms of the gastrointestinal tract. Management of GIST patients is currently based on clinicopathological features and associated genetic changes. However,...
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Synchronous Gastrointestinal Stromal Tumor and Ampullary Neuroendocrine Tumor in Association with Neurofibromatosis Type 1: A Report of Three Cases

Park EK, Kim HJ, Lee YH, Koh YS, Hur YH, Cho CK

Neurofibromatosis type 1 (NF1) is an autosomal dominant hereditary disorder. The pathogenesis of NF1 is suggested to be an alteration of the NF-1 gene, which normally functions as a tumor...
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Case of an Inflammatory Myofibroblastic Tumor of the Duodenum

Park SG, Kim GH, Park HJ, Kahng DH, Lee BE, Park DY

An inflammatory myofibroblastic tumor (IMT) is a rare disease that can occur in a variety of locations, including the lung, orbit, parotid, pleura, and stomach. Despite multiple reports in various...
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Primary Extragastrointestinal Stromal Tumor of Retroperitoneum: Poor Response to Tyrosine Kinase Inhibitor

Lee MY

Gastrointestinal stromal tumors (GIST) are the most common sarcomas arising in the gastrointestinal tract. Stromal tumors arising outside the gastrointestinal tract are known as extragastrointestinal stromal tumors (EGIST). EGISTs may...
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Metastatic Cutaneous Duodenal Gastrointestinal Stromal Tumor: A Possible Clue to Multiple Metastases

Kim YJ, Lee WJ, Won CH, Choi JH, Lee MW

We report a case of a 69-year-old man with metastatic cutaneous duodenal gastrointestinal stromal tumor, which led to find multiple metastases on orbital muscle and scalp. The patient presented with...
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Contrast Enhanced Harmonic Endoscopic Ultrasound: A Novel Approach for Diagnosis and Management of Gastrointestinal Stromal Tumors

Chhoda A, Jain D, Surabhi VR, Singhal S

The histologic analysis of gastrointestinal stromal tumors (GISTs) is a common method to detect the mitotic activity and to subsequently determine the risk of GISTs for malignancy. The potential false...
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IgG4-related Disease in the Stomach which Was Confused with Gastrointestinal Stromal Tumor (GIST): Two Case Reports and Review of the Literature

Seo HS, Jung YJ, Park CH, Song KY, Jung ES

Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated fibro-inflammatory disorder characterized by specific pathological findings and elevated serum IgG4 level. IgG4-RD in the stomach is rare, and occasionally diagnosed as gastric...
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Two different KIT mutations may lead to different responses to imatinib in metastatic gastrointestinal stromal tumor

Yim E, An HJ, Cho U, Kim Y, Kim SH, Choi YG, Shim BY

No abstract available.
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